18 Questions
Which collagen type is notably found in tendons, organ capsules, and dermis?
Type I collagen
What is the most abundant protein in the human body, representing 30% of its dry weight?
Collagen
Which type of connective tissue fiber is mainly composed of collagen type III and forms an extensive network?
Reticular fibers
In collagen assembly, what causes fibrils to have characteristic cross striations with alternating dark and light bands when observed in electron microscopy?
Overlapping arrangement of subunits
What is the family size of collagens in vertebrates?
28 collagens
Which type of collagen is responsible for forming large aggregates bundled and linked together by other collagens?
Type I collagen
Which type of connective tissue cell is responsible for the production of antibodies?
Plasma cells
What is the primary function of the ground substance in the extracellular matrix of connective tissue?
To allow for the diffusion of small molecules
Which of the following is the largest and most ubiquitous type of glycosaminoglycan (GAG) found in the extracellular matrix?
Hyaluronan
What is the primary function of the collagen fibers in connective tissue?
To provide structural support and tensile strength
Which type of connective tissue cell is responsible for the release of histamine and other inflammatory mediators?
Mast cells
Which of the following is a function of the glycosaminoglycans (GAGs) in the extracellular matrix?
To provide space-filling, cushioning, and lubricant functions
Which of the following fibers are stained black after impregnation with silver salts?
Reticular fibers
Which of the following fibers are Periodic Acid–Schiff (PAS) positive?
Reticular fibers
Which of the following cells produce reticular fibers?
Fibroblasts
Which of the following structures are surrounded by reticular fibers?
Adipocytes, smooth muscle, and nerve fibers
Which of the following tissues or organs have reticular fibers as their supportive stroma?
Liver and endocrine glands
Which of the following fibers have rubberlike properties that allow tissues containing them to be stretched or distended?
Elastic fibers
Test your knowledge on the different types of collagens and their functions in the human body. Learn about fibrillar collagens like type I, II, and III, as well as network-forming collagens such as type IV.
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