Colesevelam (Welchol) Flashcards

Colesevelam Overview

• Colesevelam is categorized as a bile acid sequestrant, a type of medication used to manage cholesterol levels.
• Primarily indicated for reducing LDL cholesterol levels in patients.

Pharmacological Action

• The main pharmacological effect is a reduction in LDL cholesterol, aiding in cardiovascular health.

Complications

• Increased dietary fiber intake is often necessary due to potential constipation, a common side effect associated with colesevelam use.

Drug Interactions

• Bile acid sequestrants, including colesevelam, may interfere with the absorption of certain medications such as levothyroxine and sulfonylureas.

Medication Administration

• Other medications should be taken at least 4 hours prior to taking bile acid sequestrants to ensure proper absorption and efficacy.

Administration Guidelines

• Colesevelam should be taken with food and accompanied by at least one glass of water to enhance tolerance and absorption.