Cohort Design Strengths & Weaknesses
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Questions and Answers

Which of the following is NOT one of Hill's criteria for assessing causation?

  • Temporal Relationship
  • Biological Plausibility
  • Consistency of Association
  • Strength of Intuition (correct)
  • According to Hill's criteria, which factor must always precede the occurrence of a disease if it is believed to cause that disease?

  • Strength of Association
  • Biological Plausibility
  • Temporal Relationship (correct)
  • Dose-Response Relationship
  • What is the purpose of Hill's criteria in epidemiological research?

  • To establish correlation without assessing causation
  • To study the genetic factors associated with diseases
  • To identify study designs offering strongest evidence (correct)
  • To assess the financial implications of a disease
  • In the context of Hill's criteria, what does 'Dose-Response Relationship' refer to?

    <p>The increase or decrease in the risk or severity of a disease with change in exposure level</p> Signup and view all the answers

    Which of the following is NOT one of Hill's criteria for assessing causation?

    <p>Frequency of Disease Occurrence</p> Signup and view all the answers

    What role does 'Strength of Association' play in Hill's criteria for assessing causation?

    <p>It assesses the strength of the causal relationship between a factor and a disease</p> Signup and view all the answers

    In an experiment, which variable is varied or manipulated by the researcher?

    <p>Independent variable</p> Signup and view all the answers

    In non-experimental research, which variable logically has some effect on a dependent variable?

    <p>Independent variable</p> Signup and view all the answers

    What is the independent variable in the scenario 'There will be a statistically significant difference in graduation rates of at-risk high-school seniors'?

    <p>Participation in study program (Y/N)</p> Signup and view all the answers

    What is the dependent variable in the scenario 'There will be a statistically significant difference in graduation rates of at-risk high-school seniors'?

    <p>Graduation rates</p> Signup and view all the answers

    Which factor is considered a predictor for commitment to the position of resident assistant?

    <p>All of the above</p> Signup and view all the answers

    What type of measurement scale uses attributes that are only named and can be ordered?

    <p>Ordinal scale</p> Signup and view all the answers

    Which level of measurement has distance as meaningful and an absolute zero?

    <p>Ratio</p> Signup and view all the answers

    What does reliability measure?

    <p>Stability and repeatability</p> Signup and view all the answers

    'A measurement must be reliable to be valid.' What does this statement imply?

    <p>'Reliable' measurements may not be valid.</p> Signup and view all the answers

    'Reliability is not a guarantee of validity.' What does this statement suggest?

    <p>'Reliable' measurements may not be valid.</p> Signup and view all the answers

    'Respect for human dignity through 3 core principles' is associated with which aspect of ethics?

    <p>'Belmont Report'</p> Signup and view all the answers

    'Treating people fairly, equitably' is related to which aspect of ethics?

    <p>'Belmont Report'</p> Signup and view all the answers

    What is a potential weakness of the cohort design related to temporality?

    <p>Difficulty in confirming that exposure precedes outcome</p> Signup and view all the answers

    Which factor limits the cohort design's ability to study rare outcomes?

    <p>Limitation in studying rare outcomes</p> Signup and view all the answers

    What is a key strength of the case-control study design in terms of exposure information?

    <p>Includes a control group to limit bias</p> Signup and view all the answers

    What is a potential weakness of the case-control study related to temporality?

    <p>Uncertainty about temporality</p> Signup and view all the answers

    What is a potential weakness of the cross-sectional/observational design in terms of exposure information?

    <p>Difficulty in obtaining accurate exposure information</p> Signup and view all the answers

    Which attribute limits the cross-sectional/observational design's ability to confirm temporality?

    <p>'No temporality' due to simultaneous measurement of outcome and exposure</p> Signup and view all the answers

    What is a common type of bias related to publication in quantitative research studies?

    <p>Publication bias (not published)</p> Signup and view all the answers

    What is essential for reducing bias related to measurement in quantitative research studies?

    <p>Validated &amp; reliable instruments for the study population</p> Signup and view all the answers

    What is confounding in the context of quantitative research studies?

    <p>An alternative explanation of findings when a factor is related to both the exposure and outcome</p> Signup and view all the answers

    What is an independent variable in quantitative research studies?

    <p>The presumed cause</p> Signup and view all the answers

    What is a dependent variable in quantitative research studies?

    <p>The presumed effect</p> Signup and view all the answers

    What type of study design would be most appropriate for evaluating the effectiveness of prevention and treatment interventions?

    <p>RCTs (Randomized Controlled Trials)</p> Signup and view all the answers

    Which criteria for establishing causality refers to the increasing amount of exposure increasing the amount of response?

    <p>Dose-Response Relationship</p> Signup and view all the answers

    What does the term 'Coherence' refer to in Hill's criteria for establishing causation?

    <p>Compatibility with existing theory and knowledge</p> Signup and view all the answers

    In epidemiological research, why is Randomized Controlled Trial (RCT) considered the most rigorous quantitative study design?

    <p>Random allocation ensures similarity between groups</p> Signup and view all the answers

    What does the term 'Specificity' refer to in Hill's criteria for establishing causation?

    <p>Presence of a single cause producing a specific effect</p> Signup and view all the answers

    Why might Randomization not always be possible in a study using the RCT design?

    <p>To address ethical and feasibility issues</p> Signup and view all the answers

    Which feature makes Cohort Analytic Design potentially less costly and/or more feasible than a Randomized Controlled Trial (RCT)?

    <p>Non-random allocation of participants</p> Signup and view all the answers

    In which study design are participants followed forward in time from exposure to outcome, similar to Randomized Controlled Trials (RCTs)?

    <p>Cohort Analytic Study</p> Signup and view all the answers

    Which criterion for establishing causality focuses on finding a consistent relationship between a factor and outcome across different studies with different populations?

    <p>Consistency of Association</p> Signup and view all the answers

    What does Hill's Criteria refer to as the weakest of criteria for causation?

    <p>Specificity</p> Signup and view all the answers

    What factor does 'Consistency of Association' focus on when establishing causality according to Hill's Criteria?

    <p>'Strength of Association'</p> Signup and view all the answers

    What makes Cohort Analytic Study different from Randomized Controlled Trials (RCTs) in terms of participant allocation?

    <p>Non-random allocation to control &amp; treatment groups</p> Signup and view all the answers

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