Cognitive Neuroscience Methods Quiz

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Questions and Answers

What is the primary focus of Cognitive Psychology?

  • Neurotransmitter functions
  • Brain activity
  • Mental operations and transformations (correct)
  • Stimulus-response mechanisms

Cognitive Neuroscience does not associate mental operations with brain activity.

False (B)

Who devised an experiment demonstrating different mental representations of letters?

Michael Posner

Cognitive Psychology assumes that we are not ______ machines.

<p>stimulus-response</p> Signup and view all the answers

Match the type of identity to its corresponding letter condition:

<p>Physical identity = A-A Phonetic identity = a-A Category identity = A-U</p> Signup and view all the answers

What technique did Posner use to demonstrate the impact of time intervals on reaction times?

<p>Stimulus onset asynchrony (A)</p> Signup and view all the answers

Reaction time differences reflect the complexity of mental representations accessed.

<p>True (A)</p> Signup and view all the answers

What kind of representations did Michael Posner demonstrate exist for letters?

<p>Different mental representations</p> Signup and view all the answers

What advantage does double dissociation studies provide in understanding cognitive functions?

<p>They demonstrate that specific tasks can have selective deficits. (D)</p> Signup and view all the answers

Double dissociations can occur without the involvement of healthy control subjects.

<p>False (B)</p> Signup and view all the answers

What is the primary limitation of group studies compared to case studies?

<p>Group studies may overlook specific deficits present in individual patients.</p> Signup and view all the answers

Electroencephalogram and ____________ are used to measure the electrical activity associated with specific tasks.

<p>magnetoencephalogram</p> Signup and view all the answers

Match the following brain imaging techniques with their primary function:

<p>fMRI = Measures changes in blood flow related to neuronal activity EEG = Measures electrical activity of the brain TMS = Creates virtual lesions by disrupting cortical processing PET = Assesses metabolic activity via blood flow changes</p> Signup and view all the answers

What is a key feature of transcranial magnetic stimulation (TMS)?

<p>It induces electrical pulses that briefly disrupt normal processing. (C)</p> Signup and view all the answers

The spatial resolution of EEG is superior to that of fMRI.

<p>False (B)</p> Signup and view all the answers

What was the specific anomia observed in the patient case mentioned?

<p>Inability to name fruits or vegetables.</p> Signup and view all the answers

In double dissociation studies, a group of patients displaying deficits in task A is compared to another group showing deficits in task __________.

<p>B</p> Signup and view all the answers

Why are case studies considered informative compared to group studies?

<p>They provide detailed individual data that can reveal specific deficits. (B)</p> Signup and view all the answers

What is one of the main findings from the Sternberg memory task?

<p>Reaction times increase with the number of letters presented (D)</p> Signup and view all the answers

Memory search operates in a parallel manner according to the Sternberg task.

<p>False (B)</p> Signup and view all the answers

What does the Stroop task demonstrate about information processing?

<p>It shows that information processing has limited capacity.</p> Signup and view all the answers

The technique that uses micro-electrodes to record neuronal activity is called _____ recordings.

<p>single cell</p> Signup and view all the answers

Match the following terms with their definitions:

<p>Encoding = Target identification Comparing = Mental representation comparison Deciding = Determining if the target was held in memory Responding = Pressing a button to convey an answer</p> Signup and view all the answers

Which technique allows for the study of gene functions in cognitive processes?

<p>Knock-out and knock-in genetic studies (D)</p> Signup and view all the answers

Single cell recordings can only be performed on awake animals.

<p>False (B)</p> Signup and view all the answers

What is one of the main limitations of individual neuron studies?

<p>They do not fully explain how cognition occurs.</p> Signup and view all the answers

In dual tasks, subjects often experience increased reaction times due to _____ capacity.

<p>limited</p> Signup and view all the answers

Which of the following is a key operation in the memory process according to Cognitive Psychology?

<p>Comparative evaluation of targets (C)</p> Signup and view all the answers

Micro-electrodes cause significant damage when inserted into the brain.

<p>False (B)</p> Signup and view all the answers

What method is used to integrate gene constructs into host genes in targeted approaches?

<p>Viral vector genetic manipulations</p> Signup and view all the answers

In the Sternberg task, the _____ increases with the number of letters presented.

<p>reaction time</p> Signup and view all the answers

What characterizes the reaction times for target rejections in the Sternberg memory task?

<p>They maintain the same slope as reaction times for positive matches. (D)</p> Signup and view all the answers

What is one consequence of high-speed bullets on the brain during wars?

<p>Localized brain lesions (A)</p> Signup and view all the answers

Repeated mild traumatic brain injury can lead to early onset dementia.

<p>True (A)</p> Signup and view all the answers

Name one common cause of brain trauma.

<p>Car accidents</p> Signup and view all the answers

The surgical removal of tissue to prevent seizures in epilepsy patients is known as _____ surgery.

<p>functional</p> Signup and view all the answers

Match the following neurological conditions with their characteristics:

<p>Epilepsy = Excessive and uncontrolled brain activity Stroke = Resulting in brain lesions and cognitive deficits Neurodegenerative diseases = Associated with aging and cognitive decline Traumatic brain injury = Resulting from incidents like sports or accidents</p> Signup and view all the answers

Which of the following is NOT a primary focus of cognitive neuroscience?

<p>Designing weapons for warfare (D)</p> Signup and view all the answers

Deep Brain Stimulation (DBS) is currently a common treatment for depression.

<p>True (A)</p> Signup and view all the answers

What is a significant concern regarding post-mortem studies of the brain?

<p>Additional damage over time</p> Signup and view all the answers

Functional neurosurgery aims to alleviate a variety of _____ symptoms.

<p>neurological</p> Signup and view all the answers

Which technique allows for focused investigation of cognitive dysfunctions?

<p>Brain imaging (B)</p> Signup and view all the answers

Cognitive neuropsychologists design tasks to show single dissociations.

<p>True (A)</p> Signup and view all the answers

What is one result of tumors on the brain?

<p>Tissue damage due to pressure or removal</p> Signup and view all the answers

Match the following types of cognitive dysfunction with their causes:

<p>Epilepsy = Uncontrolled brain activity Stroke = Large brain lesions Traumatic brain injury = Incidents like sports injuries Neurodegenerative disease = Aging population impact</p> Signup and view all the answers

What does functional neurosurgery often involve for epilepsy patients?

<p>Brain tissue extraction (D)</p> Signup and view all the answers

Cognitive dysfunction typically yields insight into healthy cognitive function.

<p>False (B)</p> Signup and view all the answers

Flashcards

Cognitive Psychology

The study of mental processes, such as perception, attention, memory, and language.

Cognitive Neuroscience

A field that combines cognitive psychology with neurobiology to investigate the brain's role in mental processes.

Mental Representation

Mental representations are internal representations of the world, like images or concepts.

Mental Operations

Mental operations refer to the processes the brain uses to manipulate mental representations.

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Levels Of Mental Representation

Different levels of mental representation exist for the same concept.

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Posner's Experiment

Posner's experiment demonstrated that accessing different levels of representation takes different amounts of time.

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Mental Representation Transformation

Mental representations can be transformed from one form to another during processing.

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Stimulus Onset Asynchrony (SOA)

The time interval between the presentation of two stimuli.

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Neurological Lesions: Studying Cognition

A technique used to study cognition by observing the cognitive deficits caused by brain damage.

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Cognitive Dysfunction

Cognitive impairment resulting from a disruption in brain function, often localized to specific brain regions.

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Neuropsychology

The study of the relationship between the brain and cognitive functions, utilizing insights from neurological disorders and brain lesions.

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Lesion Studies

A research method that involves comparing the performance of patients with lesions in different brain regions on specific cognitive tasks.

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Single Dissociation

A type of lesion study where patients with lesions in one brain region show impairment on a specific task, while patients with lesions in another region do not.

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Double Dissociation

A type of lesion study where patients with lesions in one brain region show impairment on one task, while patients with lesions in a different region show impairment on another task.

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Traumatic Brain Injury (TBI)

Cognitive impairment that occurs after a traumatic brain injury (TBI), often caused by repeated mild injuries.

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Epilepsy

A condition characterized by excessive brain activity causing disruptions in cortical processing, often resulting in seizures.

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Functional Neurosurgery

Surgical removal of brain tissue, often used as a treatment for epilepsy or other neurological conditions.

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Callosectomy

A surgical procedure that involves severing the connection between the two hemispheres of the brain.

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Lobotomy

A surgical procedure that involves severing the connections between the frontal lobes and the rest of the brain.

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Deep Brain Stimulation (DBS)

A procedure that involves implanting electrodes in the brain to stimulate specific regions.

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Prefrontal Cortex

The area of the brain responsible for higher-level cognitive function, including decision-making, planning, and abstract thinking.

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Perceptual Memory

A type of memory that allows us to see the world as coherent and continuous, despite the constant changes happening around us.

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Semantic Memory

A type of memory that allows us to remember the meaning of words and concepts.

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Double Dissociation in Task Designs

Two tasks are considered to involve non-overlapping component operations if specific manipulations affect one aspect of memory but not another, while other manipulations have the opposite effect.

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Group vs. Individual Studies: Variations in Lesions

The value of using patients to study brain-behavior relationships. Despite variations in lesion locations, comparing patient performance with lesion overlap helps identify brain regions associated with specific cognitive functions.

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Case Studies in Cognitive Neuroscience

A study of single patients with unique brain injuries to gain insights into specific cognitive functions. This can reveal insights that might be lost in larger group studies.

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Specific Anomia

The inability to name fruits or vegetables despite the ability to name other objects, such as tools.

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Electrophysiological Measurements

Non-invasive methods that directly record electrical activity in the brain. These measure the electrical activity associated with specific tasks, providing valuable insights into neuronal processing.

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Transcranial Magnetic Stimulation (TMS)

A technique that induces electrical pulses in the brain, temporarily disrupting normal processing. It creates what's known as a virtual lesion, allowing researchers to study brain function in healthy individuals.

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Virtual Lesions: Disrupting Brain Activity

The ability of TMS to disrupt specific brain regions, allowing researchers to investigate the role of these regions in various cognitive tasks.

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Limitations of TMS

The limitations associated with TMS. It mainly affects superficial and exposed cortical regions, making it unsuitable for studying deeper brain structures.

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Magnetoencephalography (MEG)

A method that uses magnetic fields to measure brain activity. It provides information about brain activity, but does not directly measure neural firing rates.

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Mental Operations in Cognitive Psychology

Mental operations are the steps or processes that occur in our minds when we perform tasks. They involve encoding information, comparing it to existing knowledge, making decisions based on that comparison, and finally, responding to the task. This involves using mental representations, attention, memory, and other cognitive processes to perform a task.

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Sternberg Memory Task

This task measures how long it takes to identify whether a specific letter was presented in a brief sequence of letters. It highlights the cognitive processes involved in visual search, encoding information, and comparing it against stored memories.

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Encoding

The process of registering and identifying information or stimuli, often the first step in a cognitive process.

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Comparing in Sternberg Task

A comparison process involved in retrieving information from memory, where encoded information is compared to existing knowledge or mental representations.

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Decision Making

A stage in cognitive processing where the brain makes a decision or judgment based on the information it has processed.

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Responding

The final stage of a cognitive process, where the brain produces a response to the task at hand, such as a physical gesture or verbal output.

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Serial Memory Search

The strategy of searching through memory one item at a time, as demonstrated in the Sternberg Memory Task.

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Limited Information Processing Capacity

The inherent limitations in our brain's capacity to process information simultaneously. This limit can lead to interference when multiple tasks or stimuli compete for attention.

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Stroop Task

A task that highlights the limitations of information processing by showing how conflicting information can interfere with our ability to respond quickly and accurately. Examples are tasks that involve naming colors of words that are printed in incongruent colors.

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Dual Tasks

Tasks that require individuals to perform two or more cognitive operations simultaneously, which can often lead to slower reaction times, increased errors, and demonstrate the limitations of our mental resources.

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Single Cell Recordings

A technique used to understand the brain's neural activity by recording electrical signals from individual neurons. These recordings provide information about how specific neurons respond to stimuli, perform tasks, and contribute to cognitive processes.

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Awake Task Performing Single Cell Recordings

These are recordings of neuronal activity taken while the animal is awake and performing a specific cognitive task. This allows researchers to examine the neural basis of higher cognitive processes like attention, memory, and decision-making.

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Genetic Manipulations in Cognitive Research

A technique used to manipulate genes in animals to understand their roles in cognitive processes. This includes creating knock-out animals where specific genes are disabled and knock-in animals where specific genes are introduced to study their effects on behavior and cognitive functions.

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Knock-Out Studies

The systematic process of selectively breeding animals to produce offspring that lack a specific gene, allowing scientists to study the effects of that missing gene on cognitive processes.

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Knock-In Studies

Studies where a specific gene is introduced into an animal's genome, allowing researchers to explore how the addition of this gene affects brain development and cognitive functions.

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Study Notes

Cognitive Neuroscience Methods

  • Cognitive Psychology vs. Cognitive Neuroscience: Cognitive Psychology examines mental operations, assuming brains extract and process environmental information before action. Cognitive Neuroscience goes further, associating mental operations with brain areas, neuronal interactions, and neurotransmitters.

Methods for Delineating Mental Representations and Operations

  • Mental Representations: Mental representations exist in different forms (e.g., physical, phonetic, categorical aspects of letters). Processing speed varies depending on the representation accessed. Different representations have varying complexities.

  • Mental Transformations: Representations are transformed during processing. Posner demonstrated this using stimulus onset asynchrony, where delays reduce reaction time differences between different representation types (e.g., physical vs. phonetic), showing transformations occur.

  • Mental Operations: Tasks are broken down into subtasks. The Sternberg memory task (identifying if a letter was in a set) showed that memory search is serial, with reaction time linearly increasing with the number of items in memory.

Information Processing Limits

  • Limited Capacity: The Stroop effect illustrates that information processing has limits (e.g., difficulty ignoring distracting information). Dual tasks demonstrate similar limits, as added tasks increase reaction times and errors.

Experimental Techniques

Animal Research

  • Single-Cell Recordings: Micro-electrodes measure the electrical activity of individual neurons in anesthetized and awake animals. This reveals the neural basis of perception, attention, memory and decision-making.

  • Multi-Electrode Recordings: Advanced technology allows simultaneous recording from many electrodes to study neural networks, not just single cell activity.

  • Genetic Manipulations: "Knock-out" studies disable genes, while "knock-in" studies insert genes. Viral vector manipulation allows targeted gene insertion or conditional expression in specific brain cells. This gives insight into genes, molecules, and cell types associated with cognitive functions.

Human Pathology (Neurology)

  • Brain Lesions: Brain injuries (from war, accidents, or disease) provide insights into relationship between brain areas and cognitive deficits. Localized lesions from precise injuries provide more focused information.

  • Cognitive Dysfunction: Studying patients with specific cognitive problems due to lesions allows scientists to associate behaviour with specific brain areas.

  • Group vs. Individual Studies: Group studies reveal commonalities while case studies detect subtle deficits.

Functional Neurosurgery

  • Lesions as Insights: Focal brain tissue removal in epilepsy patients provides insights into how specific brain areas contribute to cognitive functions.

  • Brain Imaging: Modern brain imaging techniques allow direct mapping of affected areas, crucial for analyzing and correlating brain damage and cognitive defects.

Single vs. Double Dissociations

  • Single Dissociation: One patient group shows deficit in Task A, but not Task B; the other group shows no issues. Inferences are limited.
  • Double Dissociation: Two patient groups exhibit selective deficits at two tasks. This is more powerful because neither task is more difficult.

Measuring Electrical Brain Activity Non-invasively

  • EEG and MEG: These techniques measure electrical activity directly, giving excellent temporal resolution (but poorer spatial resolution) to track neuronal processing in relation to tasks.

Virtual Lesions

  • Transcranial Magnetic Stimulation (TMS): Briefly disrupts normal cortical processing in healthy subjects, serving as a virtual lesion. Temporal and spatial resolution is important here for creating targeted "virtual disruptions".

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