Coarctation of the Aorta

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Questions and Answers

Coarctation of the aorta is characterized by which of the following?

  • Dilation of the aortic arch
  • Thickening of the mitral valve
  • Narrowing of the aortic arch (correct)
  • Enlargement of the pulmonary artery

Coarctation of the aorta typically leads to decreased blood pressure in the arteries distal to the narrowing.

True (A)

What genetic condition is commonly associated with coarctation of the aorta?

Turner syndrome

In neonates with coarctation of the aorta, a common clinical sign is weak ________ pulses.

<p>femoral</p> Signup and view all the answers

Match the following investigations with their primary purpose in diagnosing coarctation of the aorta:

<p>ECG = Detects left ventricular hypertrophy Chest X-ray = Identifies aortic shadow indentation Echocardiogram = Determines nature of coarctation MRI scan = Detailed assessment of aortic abnormalities</p> Signup and view all the answers

Which medication is typically administered to maintain ductus arteriosus patency in infants with coarctation of the aorta?

<p>Prostaglandin E1 (B)</p> Signup and view all the answers

Balloon angioplasty for coarctation of the aorta involves surgically removing the narrowed section of the aorta.

<p>False (B)</p> Signup and view all the answers

Name one potential post-treatment complication of coarctation of the aorta repair.

<p>Re-coarctation</p> Signup and view all the answers

In severe, untreated cases, coarctation of the aorta can lead to ________ failure or death.

<p>heart</p> Signup and view all the answers

What percentage range does coarctation of the aorta represent of all congenital heart defects?

<p>6-8% (C)</p> Signup and view all the answers

The etiology of coarctation of the aorta is definitively known.

<p>False (B)</p> Signup and view all the answers

What is a common early symptom in infants with coarctation of the aorta related to their feeding habits?

<p>Poor feeding</p> Signup and view all the answers

An __________ systolic murmur in the left infraclavicular region is a common clinical sign of coarctation of the aorta.

<p>ejection</p> Signup and view all the answers

Which of the following is NOT a typical clinical sign observed in infants with coarctation of the aorta?

<p>Bounding radial pulses (C)</p> Signup and view all the answers

Congestive heart failure is a possible finding on a chest X-ray of a patient with coarctation of the aorta.

<p>True (A)</p> Signup and view all the answers

What is the purpose of using dobutamine or dopamine in the medical management of coarctation of the aorta?

<p>Improve contractility</p> Signup and view all the answers

Aortic _________ is a potential complication that can occur after the treatment of coarctation of the aorta.

<p>aneurysm</p> Signup and view all the answers

What is the primary goal of administering Prostaglandin E1 to a neonate with coarctation of the aorta?

<p>To maintain patency of ductus arteriosus (C)</p> Signup and view all the answers

Coarctation of the aorta can only be diagnosed in infancy and cannot be detected antenatally.

<p>False (B)</p> Signup and view all the answers

Besides balloon angioplasty, name one other surgical option for correcting coarctation of the aorta.

<p>Bypass graft</p> Signup and view all the answers

In the context of coarctation of the aorta, a difference in blood pressure between the arms and legs is a clinical sign indicative of reduced blood flow to the __________ extremities.

<p>lower</p> Signup and view all the answers

Which investigation is most useful to identify any other associated cardiac abnormailities alongside coarctation of the aorta?

<p>Echocardiogram (C)</p> Signup and view all the answers

Male gender is considered as protective factor against coarctation of the aorta

<p>False (B)</p> Signup and view all the answers

What does ductal-dependent mean when describing a congenital heart condition?

<p>Patent ductus arteriosus dependent</p> Signup and view all the answers

Left ventricular _________ may be observed on an ECG of a patient with severe coarctation of the aorta

<p>hypertrophy</p> Signup and view all the answers

Flashcards

Coarctation of the Aorta

Narrowing of the aortic arch, typically near the ductus arteriosus.

Aetiology of Coarctation

Under-development of the aortic arch in utero or ductal tissue expanding into the aorta.

Risk Factors for Coarctation

Male gender, Turner syndrome, family history, bicuspid aortic valve & other congenital heart defects.

Symptoms of Coarctation in Infants

Poor feeding, tachypnoea, increased work of breathing, irritability, grey/floppy appearance.

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Clinical Signs of Coarctation

Weak femoral pulses, ejection systolic murmur, unequal blood pressure in arms, cold extremities.

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Investigations for Coarctation

ECG, chest X-ray, echocardiogram, MRI.

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Management of Coarctation

Prostaglandin E1, dobutamine/dopamine, supportive care, surgery.

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Complications of Untreated Coarctation

Heart failure, chronic hypertension, aneurysm, aortic dissection.

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Post-Treatment Complications

Re-coarctation, aortic aneurysm/rupture, persistent hypertension.

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Ductal-Dependent Congenital Heart Condition

A defect requiring a patent ductus arteriosus for systemic or pulmonary blood flow.

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Effect of Coarctation on the Heart

Left Ventricular Hypertrophy

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Differentials for resistant hypertension

Aortic Stenosis, Cardiomyopathies, Primary Hypertension, Viral Myocarditis.

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Medical Management: Prostaglandin E1

Using Prostaglandin E1 to maintain ductus arteriosus patency before surgery.

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Surgical Management Options

Balloon angioplasty or resection with end-to-end anastomosis.

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Pulse Oximetry

Measurement of oxygen saturation to detect congenital heart defects.

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Rib Notching

Indentations on the underside of ribs due to collateral vessel development.

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Study Notes

  • Coarctation of the aorta involves the narrowing of the aortic arch, typically near the ductus arteriosus or ligamentum arteriosum.
  • It accounts for 6-8% of congenital heart defects.

Aetiology

  • The exact cause remains unclear.
  • One theory suggests under-development in utero because of reduced blood flow.
  • Another theory involves ductal tissue expanding into the thoracic aorta, causing constriction after birth.
  • It leads to left ventricular hypertrophy and reduced pressure in distal arteries.

Risk factors

  • Male gender increases the risk.
  • Genetic conditions like Turner syndrome are risk factors.
  • A family history contributes to the risk.
  • Commonly associated with other congenital heart defects, like a bicuspid aortic valve.

Symptoms

  • In infants, symptoms include poor feeding, tachypnoea, and increased work of breathing.
  • Irritability and a grey/floppy appearance can also be indicative.
  • Antenatal detection is possible, but it can remain undiagnosed until adulthood.

Clinical signs

  • Weak femoral pulses are a common sign in neonates.
  • An ejection systolic murmur may be heard in the left infraclavicular region.
  • Unequal blood pressure between arms can be observed.
  • Differences in pre and post-ductal oxygen saturations are notable.
  • Cold extremities are often present.
  • Later signs may include a left ventricular heave and radio/radial-femoral delay.

Investigations

  • ECG results may be normal or show left ventricular hypertrophy.
  • Chest X-rays may reveal indentation of the aortic shadow, rib notching, or congestive heart failure.
  • Echocardiograms help assess the coarctation and associated abnormalities.
  • MRI provides detailed assessment of the coarctation and any related issues.

Management

  • Prostaglandin E1 maintains ductus arteriosus patency.
  • Dobutamine or dopamine can manage heart failure.
  • Supportive care is essential.
  • Surgical options include balloon angioplasty, resection with end-to-end anastomosis, or bypass graft.

Complications

  • Untreated severe coarctation can result in heart failure or death.
  • Chronic hypertension is a common complication.
  • Other complications include brain aneurysm rupture, brain haemorrhage, and aortic dissection.
  • Aortic aneurysm, congestive heart failure, and irreversible heart damage can also occur.

Post-treatment complications

  • Re-coarctation is possible.
  • Aortic aneurysm or rupture can develop.
  • Persistent hypertension may occur.

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