Coagulation and Platelet Disorders Quiz
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Questions and Answers

Which of the following symptoms is not associated with thrombosis?

  • Cyanosis at skin
  • Renal failure and hematuria
  • Petechiae and ecchymosis on skin (correct)
  • Dyspnea
  • What is the initial event in the main problem described?

  • Dyspnea
  • Widespread bleeding
  • Renal failure and hematuria
  • Sx thrombi (correct)
  • What is the primary cause of poor clotting in liver disease?

  • Poor bile production
  • Poor production of clotting factors (correct)
  • Vitamin K absorption
  • Hematuria
  • What is the recommended treatment for clotting in lungs or kidney (or brain)?

    <p>Fibrinolytics</p> Signup and view all the answers

    What is the consequence of depleted platelet stores?

    <p>Widespread bleeding</p> Signup and view all the answers

    Which organ is responsible for making most of the clotting factors?

    <p>Liver</p> Signup and view all the answers

    What is the recommended treatment for poor clotting due to liver disease?

    <p>Plasma transfusion</p> Signup and view all the answers

    What is the consequence of thrombosis at pulmonary capillaries?

    <p>Dyspnea</p> Signup and view all the answers

    What is the primary cause of poor clotting in liver disease?

    <p>Poor production of clotting factors</p> Signup and view all the answers

    What are the specific clotting factors that result in enzymatic cleavage of fibrinogen?

    <p>Factor X and Factor XI</p> Signup and view all the answers

    Why does a normal platelet count not ensure adequate platelet function?

    <p>Platelet aggregation disorders may be present</p> Signup and view all the answers

    What proteins/cells/vitamins are needed for proper clotting and where do they come from?

    <p>Factor VIII from liver, Factor IX from platelets, Vitamin K from diet</p> Signup and view all the answers

    What are the causes and symptoms of thrombocytopenia?

    <p>Causes: decreased platelet production; Symptoms: increased risk of bleeding</p> Signup and view all the answers

    What treatments or disease states lead to coagulation disorders?

    <p>Liver disease; Factor V Leiden mutation</p> Signup and view all the answers

    What are the roles of the intrinsic and extrinsic pathways in clotting?

    <p>Intrinsic: initiated by tissue factor; Extrinsic: initiated by exposed collagen</p> Signup and view all the answers

    What are the steps in hemostasis?

    <p>Vasoconstriction, platelet aggregation, coagulation, clot retraction</p> Signup and view all the answers

    Which pathway of coagulation is dependent on vitamin K?

    <p>Common pathway</p> Signup and view all the answers

    What is the primary role of platelets in hemostasis?

    <p>Aggregating at the site of injury</p> Signup and view all the answers

    Which process is initiated shortly after clot formation?

    <p>Fibrinolysis</p> Signup and view all the answers

    What is the key organ responsible for synthesizing most coagulation factors?

    <p>Liver</p> Signup and view all the answers

    Which lab finding is used to evaluate the extrinsic pathway of coagulation?

    <p>Prothrombin time (PT)</p> Signup and view all the answers

    What does hemostasis involve?

    <p>Vessel walls, platelets, and coagulation proteins</p> Signup and view all the answers

    What can hemostasis lead to with excessive clotting or bleeding?

    <p>Thrombosis</p> Signup and view all the answers

    Which disorder presents as chronic dilation of capillaries with localized red or purple lesions?

    <p>Hereditary Hemorrhagic Telangiectasia</p> Signup and view all the answers

    What are the characteristics of Hemophilia A and B?

    <p>Factor VIII and IX deficiencies, leading to bleeding, hemarthrosis, and joint deformities</p> Signup and view all the answers

    What does D dimer measure in the body?

    <p>Factors in clotting pathways, indicating high fibrin degradation products</p> Signup and view all the answers

    What are the possible causes of vascular disorders such as purpura?

    <p>Drug-induced, autoimmune, or related to connective tissue disorders</p> Signup and view all the answers

    What are the etiological factors of Thrombocytopenia?

    <p>Decreased production, survival, pooling in the spleen, and dilution due to transfusions</p> Signup and view all the answers

    What are the potential consequences of Thrombocytosis?

    <p>Transient, secondary, or primary, leading to hemorrhage, occlusion of vessels, and tissue necrosis</p> Signup and view all the answers

    What do qualitative platelet disorders such as von Willebrand disease, Bernard-Soulier syndrome, and thrombasthenia result in?

    <p>Bleeding and increased bleeding time</p> Signup and view all the answers

    Study Notes

    Coagulation and Platelet Disorders Overview

    • D dimer measures factors in clotting pathways, indicating high fibrin degradation products in the body
    • PT and PTT interpretations for bleeding or clotting syndromes include examples of conditions associated with prolonged or normal results
    • Vascular disorders such as purpura can be drug-induced, autoimmune, or related to connective tissue disorders
    • Hereditary Hemorrhagic Telangiectasia presents as chronic dilation of capillaries, with localized red or purple lesions
    • Thrombocytopenia's etiology includes decreased production, survival, pooling in the spleen, and dilution due to transfusions
    • Thrombocytosis can be transient, secondary, or primary, leading to hemorrhage, occlusion of vessels, and tissue necrosis
    • Qualitative platelet disorders include von Willebrand disease, Bernard-Soulier syndrome, and thrombasthenia, resulting in bleeding and increased bleeding time
    • Hemophilia A and B are characterized by factor VIII and IX deficiencies, leading to bleeding, hemarthrosis, and joint deformities
    • DIC involves widespread clotting and fibrinolysis, associated with snakebites, malignancy, transfusion reactions, and shock
    • Measures and interpretations of PT, PTT, D dimer, and platelet counts are essential for diagnosing coagulation and platelet disorders
    • Treatment options for these disorders include drug therapy, transfusions, injury prevention, and administration of deficient factors
    • Understanding the etiology, symptoms, and treatment options for coagulation and platelet disorders is crucial for effective management and patient care

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    Description

    Test your knowledge of coagulation and platelet disorders with this informative quiz. Explore key concepts such as D dimer, PT and PTT interpretations, vascular disorders, hereditary hemorrhagic telangiectasia, thrombocytopenia, thrombocytosis, qualitative platelet disorders, hemophilia, DIC, diagnostic measures, and treatment options. Gain a deeper understanding of the etiology, symptoms, and management of these important medical conditions.

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