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Questions and Answers
What class does Clonazepam (Klonopin) belong to?
What are the expected pharmacological actions of Clonazepam?
Anticonvulsant effects may be due to presynaptic inhibition and it produces sedative effects in the CNS by stimulating inhibitory GABA receptors.
What are the therapeutic uses of Clonazepam?
Clonazepam can lead to __________ thoughts as a complication.
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What are some complications associated with Clonazepam use?
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Which of the following is a contraindication for Clonazepam?
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What precautions should be taken when using Clonazepam?
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Study Notes
Clonazepam Overview
- Clonazepam is classified as an anticonvulsant and a benzodiazepine.
Pharmacological Action
- Anticonvulsant effects may be linked to presynaptic inhibition.
- Produces central nervous system (CNS) sedative effects by stimulating inhibitory GABA receptors.
Therapeutic Uses
- Primarily used for the prevention of seizures.
- Effective in decreasing symptoms associated with panic disorder.
Complications (Adverse Reactions/Side Effects)
- CNS: Possible suicidal thoughts, behavioral changes, drowsiness, fatigue, slurred speech, ataxia, sedation, abnormal eye movements, diplopia, nystagmus.
- Respiratory: Increased secretions.
- Cardiovascular: Palpitations.
- Dermatological: Rash.
- Gastrointestinal: Constipation, diarrhea, hepatitis, weight gain.
- Genitourinary: Dysuria, nocturia, urinary retention.
- Hematological: Anemia, eosinophilia, leukopenia, thrombocytopenia.
- Neurological: Ataxia, hypotonia.
- Miscellaneous: Fever, potential for physical and psychological dependence, tolerance development.
Contraindications/Precautions
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Contraindicated in:
- Hypersensitivity to the drug.
- Severe hepatic impairment.
- Pregnant individuals, as it may cause fetal harm.
- Breastfeeding due to risks to the infant.
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Use Cautiously in:
- All patients due to potential increased risk of suicidal thoughts/behaviors.
- Conditions like angle-closure glaucoma, obstructive sleep apnea, chronic respiratory disease, and history of porphyria.
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Geriatric Considerations: Older adults may experience excessive sedation at standard doses; dosage reduction is recommended.
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Pediatric Considerations: Caution is advised when prescribing to children.
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Description
Test your knowledge of Clonazepam (Klonopin) with these flashcards. Explore its categories, pharmacological actions, and therapeutic uses. This quiz is essential for students learning about medications and their effects.
