CLL Diagnosis and Classification
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Questions and Answers

What is the diagnostic criterion for circulating clonal B cells?

  • >5 x10e9/l persisting for >3 months (correct)
  • >3 x10e9/l persisting for >1 month
  • >2 x10e9/l persisting for >2 months
  • >10 x10e9/l persisting for >6 months

    • What is the significance of a CLL Score of 4 or 5?

  • Occurs in 92% of CLL cases (correct)
  • Is a significant predictor of prognosis
  • Indicates aggressive CLL
  • Indicates early-stage CLL

    • What is the characteristic surface immunophenotype of CLL?

  • Surface Ig weak, CD5+, CD23+, CD79b- (correct)
  • Surface Ig strong, CD5-, CD23-, CD79b+
  • Surface Ig weak, CD5-, CD23+, CD79b+
  • Surface Ig strong, CD5+, CD23-, CD79b+

    • What is the diagnosis when >15% prolymphocytes are present?

    <p>Prolymphocytic progression of CLL</p> Signup and view all the answers

    What is the term for a CD5+ monoclonal B cell lymphocytosis that is detectable on a routine FBC?

    <p>Monoclonal B cell lymphocytosis (MBL)</p> Signup and view all the answers

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