CLIN.PARASITOLOGY: Malaria
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Questions and Answers

Which parasite causes Blackwater fever or malarial hemoglobinuria, a dangerous complication of malaria?

  • Plasmodium ovale
  • Plasmodium vivax
  • Plasmodium falciparum (correct)
  • Plasmodium malariae
  • What is the least frequent type of malaria among humans, mostly acquired in Western Africa, India, or South America?

  • Plasmodium vivax
  • Plasmodium malariae
  • Plasmodium falciparum
  • Plasmodium ovale (correct)
  • During a malarial attack, what occurs over 6-10 hours due to the synchronous rupture of erythrocytes?

  • Increased heart rate
  • Formation of blood clots
  • Resolution of fever (correct)
  • Onset of diarrhea
  • Which species of Plasmodium is found throughout Southeast Asia and is the most common cause of human Malaria in Malaysia?

    <p>Plasmodium knowlesi</p> Signup and view all the answers

    Which Plasmodium species occurs principally in tropical areas worldwide and is one of the most dangerous complications of malaria?

    <p>Plasmodium falciparum</p> Signup and view all the answers

    Which type of mosquito exclusively spreads malaria?

    <p>Female Anopheline mosquitoes</p> Signup and view all the answers

    What is the impact of G6PD deficiency on red blood cells?

    <p>Increased oxidative stress</p> Signup and view all the answers

    In which region is Plasmodium knowlesi the most common cause of human malaria?

    <p>Malaysia</p> Signup and view all the answers

    Which Plasmodium species is most closely related to P.knowlesi?

    <p>Plasmodium vivax</p> Signup and view all the answers

    What is the treatment commonly recommended for P.knowlesi malaria?

    <p>Chloroquine or artemisinin combination therapy</p> Signup and view all the answers

    How can humans become infected with P.knowlesi?

    <p>By being fed upon by infected mosquitoes</p> Signup and view all the answers

    Why is P.knowlesi malaria considered an emerging disease?

    <p>Because it was previously thought to be rare in humans but is now recognized as a major health burden</p> Signup and view all the answers

    Why are individuals with the AS genotype resistant to Falciparum malaria?

    <p>Their red blood cells sickle after infection, making them less susceptible to the parasite.</p> Signup and view all the answers

    What is the role of Duffy blood group determinants in protecting against certain types of malaria infections?

    <p>They act as chemokine receptors, preventing the entry of Plasmodium species.</p> Signup and view all the answers

    How does Glucose-6-phosphate dehydrogenase (G6PD) deficiency contribute to protection against malaria?

    <p>It causes the rupture of red blood cells, limiting the spread of the infection.</p> Signup and view all the answers

    What is the main reason why individuals lacking Duffy blood group determinants have resistance to malaria?

    <p>They have a higher frequency of Fy(a-b-) in their population.</p> Signup and view all the answers

    How does the sickling of red blood cells contribute to resistance against Falciparum malaria?

    <p>It increases the likelihood of hemolysis, which eliminates infected cells.</p> Signup and view all the answers

    Why do Africans and Arabs have a higher frequency of being Fy(a-b-) compared to other populations?

    <p>They have evolved a resistance due to historical exposure to malaria.</p> Signup and view all the answers

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