Clinical Trials and Stem Cells Quiz

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20 Questions

Why are human pluripotent stem cells (hPSCs) preferred in drug screening due to their advantages?

Have the potential to differentiate into any cellular fate

Unlike an embryonic stem cell, a tissue stem cell...

Can only give rise to limited number of cell types

Which one is NOT an example of cancer treatment by using stem cells?

Replacing cancerous hematopoietic cells with healthy bone marrow stem cells

Cells or tissue donated by a related or unrelated individual are called...

Allogenic

Which of the following is NOT a way that genes can be introduced into the stem cells in gene therapy?

Bacteria

In human clinical trials, which phase refers to the first testing of a new drug, treatment, or clinical device on a small group of people?

Phase 1

Which of the following is NOT a criteria for pluripotency of embryonic stem cells?

Commitment for differentiation to several cell types

What is a valid characteristic of a 'multipotent' stem cell?

Can be obtained at blastocyst stage of embryonic development

A cancer stem cell can divide to give rise to...

Cancer stem cells, progenitor cells, improperly differentiated tumor cells

What is a blastocyst?

A very early-stage embryo

What is the primary criteria for pluripotency of embryonic stem cells?

Commitment for differentiation to several cell types

Which phase of the human clinical trials involves the first testing of a new drug, treatment, or clinical device on a small group of people?

Phase 1

What is a blastocyst?

A very early-stage embryo

What distinguishes a tissue stem cell from an embryonic stem cell?

Can be obtained at blastocyst stage of embryonic development

What can a cancer stem cell divide to give rise to?

Cancer stem cells, progenitor cells, improperly differentiated tumor cells

What is the correct order in Gene-directed enzyme prodrug therapy by Mesenchymal Stem cells (MSCs) against cancer?

Pro-drug is catalyzed by the enzymatic cleavage to the activated form within the tumor environment

Why human pluripotent stem cells (hPSCs) are preferred in drug screening due to their advantages?

Have the potential to differentiate into any cellular fate

Which one is NOT a property of an ideal scaffold in tissue engineering?

Inaccessibility of cells into the scaffold

Which stem cells have the most potency?

Totipotent

Which of the following is NOT a way that genes can be introduced into the stem cells in gene therapy?

Bacteria

Test your knowledge about human clinical trials phases and criteria for pluripotency and multipotency of stem cells with this quiz.

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