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Clinical Trials and Research Methodology
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Clinical Trials and Research Methodology

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Questions and Answers

What is the primary goal of an experimental study?

  • To identify the proportion of children with a particular disease
  • To relate past factors to the present state
  • To track changes over time and relate them to variables
  • To establish a causal relationship between variables (correct)
  • Which type of study is used to estimate the proportion of children with diarrhea?

  • Cross-sectional study (correct)
  • Longitudinal study
  • Retrospective study
  • Case-control study
  • In a longitudinal study, what is measured?

  • The direction of causal relationships
  • Proportion of children with a particular disease
  • Change in variables over two or more distinct time periods (correct)
  • Change in variables over a single time period
  • What is the primary focus of a case-control study?

    <p>To collect data for two different groups of people</p> Signup and view all the answers

    What is the purpose of a retrospective study?

    <p>To study the possible factors in the past that are related to the present state</p> Signup and view all the answers

    Which type of study is also known as a clinical trial?

    <p>Interventional study</p> Signup and view all the answers

    What is the main difference between a cross-sectional study and a longitudinal study?

    <p>The duration of data collection</p> Signup and view all the answers

    Which type of study is used to describe patterns of change and establish causal relationships?

    <p>Longitudinal study</p> Signup and view all the answers

    What is the main purpose of a descriptive study?

    <p>To explore a certain situation and describe it</p> Signup and view all the answers

    What type of study is used to examine the relationship between variables?

    <p>Analytical study</p> Signup and view all the answers

    What is the main purpose of an experimental study?

    <p>To test the effect of an intervention</p> Signup and view all the answers

    What type of study is used to study a group of individuals over a long period of time?

    <p>Longitudinal study</p> Signup and view all the answers

    What type of study is used to study a group of individuals at a single point in time?

    <p>Cross-sectional study</p> Signup and view all the answers

    What is the purpose of defining the main purpose of a study?

    <p>To determine the type of study design</p> Signup and view all the answers

    What is important to consider when selecting a study design?

    <p>The purpose of the study</p> Signup and view all the answers

    What is the benefit of a literature review in research?

    <p>It brings ease to the research process</p> Signup and view all the answers

    What is the purpose of a control group in a study?

    <p>To compare with a case group to determine if specific behaviors are related to a disease</p> Signup and view all the answers

    Which type of study involves studying a group of individuals with some common features over time?

    <p>Longitudinal study</p> Signup and view all the answers

    What is the main challenge in matching individuals in a control group to those in a case group?

    <p>Finding individuals with the same weight and height</p> Signup and view all the answers

    What is the focus of a case-control study?

    <p>Comparing individuals with a disease to those without the disease</p> Signup and view all the answers

    Which type of study is used to study a group of individuals who are born in the same year?

    <p>Cohort study</p> Signup and view all the answers

    What is the term for matching individuals in a control group to those in a case group?

    <p>Matching</p> Signup and view all the answers

    Study Notes

    Clinical Trials and Study Types

    • Clinical trials involve studying the best treatment regimens and are allowed even if there is an expected harmful effect.
    • Example: finding whether survival time of cancer breast females who receive radiotherapy first then surgery is longer than surgery treatment alone.

    Types of Study Designs

    • Cross-sectional study: single time recording of events, e.g., studying the proportion of children with diarrhea.
    • Longitudinal studies: follow the same sample over time, making repeated observations, e.g., tracking changes in a group of people over time.
    • Retrospective study: studying possible factors in the past related to the present state, e.g., relating diabetes mellitus to past consumption of fatty diets.

    Group of Study

    • Case-control: collecting data for two groups, cases (group of concern) and control (comparable group), e.g., studying the relationship between specific behaviors and disease.
    • Cohort: studying a group of individuals with some common features, e.g., studying goitre among a group living away from the sea.

    Literature Review

    • Researchers should consider relevant background information, what information is needed, and how it will be used in decision-making.
    • Literature review involves studying academic journals, conference and government reports, and library resources.

    Making Hypothesis

    • Hypothesis development is a technical process that depends on the researcher's experience.
    • Hypothesis narrows down the research area and keeps the researcher on the right path.

    Research Design

    • Research design is prepared after formulating the problem and creating a hypothesis.
    • It involves drawing the conceptual structure of the problem and may involve different types of research designs.

    Study Aims

    • Descriptive study: explores a situation and describes it, e.g., estimating disease prevalence or describing symptoms.
    • Analytical study: examines how or why certain phenomena are present, e.g., studying why Japanese women have lower prevalence of cancer breast.
    • Experimental study: involves intervention and is used to study the effect of a specific intervention, e.g., extending outpatient service time to improve service quality.

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    Description

    This quiz assesses understanding of clinical trials, research methodology, and study design. It covers topics such as interventions, treatment regimens, and data collection.

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