10 Questions
What are factors that increase the risk of adverse clinical outcomes and mortality in elderly hemodialysis (HD) patients?
Nutritional and inflammatory disorders
Where was the case–control study conducted?
Universidad San Pablo-CEU, Madrid, Spain
How many older participants were involved in the case–control study?
168
What type of patients were examined in the study?
Elderly hemodialysis (HD) patients
What kind of parameters were collected from medical records in the study?
Demographic, clinical, anthropometric, and laboratory parameters
What was the aim of the study?
To investigate the effect of thylakoid membranes of spinach and calorie-restriction on gut-brain axis pathway and oxidative stress biomarkers in obese women with PCOS
How many women were assigned to the thylakoid group?
21
What is the significance of higher intestinal mucosal permeability in women with PCOS?
It leads to lipopolysaccharide (LPS) leakage and endotoxemia
What are the neurotrophic factors assessed in the study?
Brain-derived neurotrophic factor (BDNF) and S100 calcium-binding protein B (S100 B)
What type of trial was conducted in this study?
Double-blind, randomized, placebo-controlled clinical trial
Study Notes
- Nutritional and inflammatory disorders are linked to increased risk of adverse clinical outcomes and mortality in elderly hemodialysis (HD) patients.
- A case–control study was carried out to examine nutritional and inflammation status, as well as body composition, in older HD patients compared to age- and sex-matched controls.
- The study involved 168 participants, consisting of 84 HD patients (cases) and 84 controls.
- Data was collected from medical records on demographics, clinical, anthropometric, and laboratory parameters.
- The study was conducted at the Department of Pharmaceutical & Health Sciences, School of Pharmacy, Universidad San Pablo-CEU, and the Nephrology Department, Hospital Universitario La Princesa.
Explore the clinical significance of nutritional status, inflammation, and body composition in elderly hemodialysis patients through a case-control study. Gain insights into the impact of these factors on the health and well-being of the elderly undergoing hemodialysis treatment.
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