Clinical Significance of Nutritional Status in Elderly Hemodialysis Patients

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Questions and Answers

What are factors that increase the risk of adverse clinical outcomes and mortality in elderly hemodialysis (HD) patients?

  • Nutritional and inflammatory disorders (correct)
  • Genetic and environmental factors
  • Medication and treatment adherence
  • Psychological and social factors

Where was the case–control study conducted?

  • Oxford University, London, UK
  • Universidad San Pablo-CEU, Madrid, Spain (correct)
  • Sorbonne University, Paris, France
  • Harvard University, Boston, USA

How many older participants were involved in the case–control study?

  • 1000
  • 50
  • 500
  • 168 (correct)

What type of patients were examined in the study?

<p>Elderly hemodialysis (HD) patients (A)</p> Signup and view all the answers

What kind of parameters were collected from medical records in the study?

<p>Demographic, clinical, anthropometric, and laboratory parameters (A)</p> Signup and view all the answers

What was the aim of the study?

<p>To investigate the effect of thylakoid membranes of spinach and calorie-restriction on gut-brain axis pathway and oxidative stress biomarkers in obese women with PCOS (B)</p> Signup and view all the answers

How many women were assigned to the thylakoid group?

<p>21 (C)</p> Signup and view all the answers

What is the significance of higher intestinal mucosal permeability in women with PCOS?

<p>It leads to lipopolysaccharide (LPS) leakage and endotoxemia (D)</p> Signup and view all the answers

What are the neurotrophic factors assessed in the study?

<p>Brain-derived neurotrophic factor (BDNF) and S100 calcium-binding protein B (S100 B) (B)</p> Signup and view all the answers

What type of trial was conducted in this study?

<p>Double-blind, randomized, placebo-controlled clinical trial (B)</p> Signup and view all the answers

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Study Notes

  • Nutritional and inflammatory disorders are linked to increased risk of adverse clinical outcomes and mortality in elderly hemodialysis (HD) patients.
  • A case–control study was carried out to examine nutritional and inflammation status, as well as body composition, in older HD patients compared to age- and sex-matched controls.
  • The study involved 168 participants, consisting of 84 HD patients (cases) and 84 controls.
  • Data was collected from medical records on demographics, clinical, anthropometric, and laboratory parameters.
  • The study was conducted at the Department of Pharmaceutical & Health Sciences, School of Pharmacy, Universidad San Pablo-CEU, and the Nephrology Department, Hospital Universitario La Princesa.

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