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Clinical Significance of Blood Glucose Levels

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5 Questions

Which of the following ranges correctly represents normal fasting plasma glucose levels?

3.9-5.6 mmol/L

What is a defining characteristic of hyperglycemia?

High plasma glucose levels

In type 2 diabetes, hyperglycemia primarily results from which condition?

Relative resistance to insulin action

Which definition correctly describes glucose intolerance?

Metabolic conditions resulting in higher than normal glucose levels

What percentage of the plasma glucose value represents the typical CSF glucose level?

60%

Study Notes

Normal Range

  • Normal fasting plasma glucose levels range from 3.9-5.6 mmol/L (70-100 mg/dl)
  • CSF glucose levels are typically between 2.2 – 4.2 mmol/L (40-75 mg/dl) or approximately 60% of plasma value

Hyperglycemia

  • Hyperglycemia is characterized by high levels of sugar (glucose) in the blood
  • It occurs due to:
    • Lack of insulin production in the body (type 1 diabetes)
    • Insulin resistance, where the body does not respond effectively to insulin (type 2 diabetes)
  • Insulin is a hormone that facilitates glucose absorption into cells for energy production
  • Glucose intolerance is a broader term encompassing metabolic conditions that result in elevated blood glucose levels

This quiz covers normal range and hyperglycemia of blood glucose levels, including factors contributing to high sugar levels in the blood such as insulin resistance and type 1 and 2 diabetes.

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