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Questions and Answers
Living cells capable of cell division are the most critical requirement for ___________ examination.
Living cells capable of cell division are the most critical requirement for ___________ examination.
karyograms
The sample collection and handling process greatly influences whether or not the cells will grow and divide, and the quality of the resulting ___________.
The sample collection and handling process greatly influences whether or not the cells will grow and divide, and the quality of the resulting ___________.
metaphases
Specimen containers used for cell culture must be ________ and labeled with the patient’s name and a second identifier.
Specimen containers used for cell culture must be ________ and labeled with the patient’s name and a second identifier.
sterile
Peripheral blood samples should be collected in _________ syringes or vacuum tubes containing preservative-free sodium heparin.
Peripheral blood samples should be collected in _________ syringes or vacuum tubes containing preservative-free sodium heparin.
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Outdated vacuum tubes for blood samples should be __________.
Outdated vacuum tubes for blood samples should be __________.
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Living cells for cell culture should be received in a manner that ensures they are capable of ________.
Living cells for cell culture should be received in a manner that ensures they are capable of ________.
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The final steps of the process typically involve a clerical review of all relevant clinical, technical, and clerical data, examination of the patient’s chart and karyograms by the laboratory director, and generation of the formal clinical ______.
The final steps of the process typically involve a clerical review of all relevant clinical, technical, and clerical data, examination of the patient’s chart and karyograms by the laboratory director, and generation of the formal clinical ______.
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In addition to the appropriate physician and patient demographic information, the patient's file should include the number of metaphases that were examined microscopically, the banding resolution obtained for the specimen, and the number of cells that were analyzed in ______.
In addition to the appropriate physician and patient demographic information, the patient's file should include the number of metaphases that were examined microscopically, the banding resolution obtained for the specimen, and the number of cells that were analyzed in ______.
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The laboratory director is responsible for the examination of the patient’s chart and karyograms, often preceded by the supervisor and/or other senior laboratory personnel, before the generation of the formal clinical ______.
The laboratory director is responsible for the examination of the patient’s chart and karyograms, often preceded by the supervisor and/or other senior laboratory personnel, before the generation of the formal clinical ______.
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The final clinical report should include the patient’s karyotype, the number of karyograms prepared, and the clinical interpretation of the results, including recommendations for additional testing and/or genetic ______.
The final clinical report should include the patient’s karyotype, the number of karyograms prepared, and the clinical interpretation of the results, including recommendations for additional testing and/or genetic ______.
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The purpose of this chapter is to provide a general overview of the many steps involved from receipt of a sample in the cytogenetics laboratory to the generation of a patient report and to impress upon the reader the ______ nature of this work.
The purpose of this chapter is to provide a general overview of the many steps involved from receipt of a sample in the cytogenetics laboratory to the generation of a patient report and to impress upon the reader the ______ nature of this work.
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Summary information recorded in the patient’s file is used in the clinical report and should include patient karyotype, banding resolution, number of cells examined, analyzed, imaged, etc., and is part of the final steps of the process before the generation of the formal clinical ______.
Summary information recorded in the patient’s file is used in the clinical report and should include patient karyotype, banding resolution, number of cells examined, analyzed, imaged, etc., and is part of the final steps of the process before the generation of the formal clinical ______.
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Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
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All of these in turn depend upon individuals with the appropriate expertise and dedication to patient care. Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
All of these in turn depend upon individuals with the appropriate expertise and dedication to patient care. Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
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Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
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Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
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Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
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Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
Due to the nature of this chapter, individual citations were not always practical. In addition to the references cited below and the authors’ personal experience, the following were used as supplemental sources of information: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetic laboratory manual. Philadelphia: Raven-Lippincott; 1997. 65 Rooney DE, editor. Human cytogenetics: constitutional analysis. 3rd ed. Oxford: Oxford University Press; 2001. Rooney DE, Czepulkowski BH, editors. Human cytogenetics: a practical approach, volume I constitutional analysis. New York: IRL Press, Oxford University Press; 1992. Verma RS, Babu A. Human chromosomes. New York: McGraw-Hill, Inc.; 1995. The American College of Medical Genetics (ACMG) Standards and Guidelines for Clinical Genetics Laboratories. ACMG 2009 Edition/ Revised 01/2010; www.acmg.net/StaticContent/SGs/Section_E_ 2011.pdf. References 1. Dicker F, Schnittger S, Haferlach T, Kern W, Schoch C.
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