Clinical Micro Chapter 8 Flashcards
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Questions and Answers

Match the Lancefield group to the correct species:

S.equismimilis = C S.bovis group = D, non-Enterococcus S.agalactiae = B E.faecalis = D, Enterococcus S.mutans = None S.pyogenes = A E.faecium = Enterococcus, D S.anginosus = F

Lancefield's classification of Streptococcus is based on?

Cell wall polysaccharide

Streptolysin O is?

Antigenic

What would be an incorrect reaction for Enterococcus?

<p>PYR negative</p> Signup and view all the answers

Sequelae of group ___________________________ infection may lead to acute rheumatic fever or acute glomerulonephritis.

<p>A Streptococcus</p> Signup and view all the answers

Colonies of Streptococcus pneumoniae at 24 hours are typically?

<p>mucoid and a-hemolytic</p> Signup and view all the answers

What are the best tests to identify B-hemolytic streptococci isolated from a throat culture of a 15-year-old male?

<p>Bacitracin and PYRase</p> Signup and view all the answers

What is the expected reaction of the B-hemolytic streptococci for Species: Streptococcus pyogenes?

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What is the expected reaction of the B-hemolytic streptococci for Species: Streptococcus agalactiae?

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What is the expected reaction of the B-hemolytic streptococci for Species: Groups C, F, and G?

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What is the expected reaction for the a-hemolytic and non-hemolytic streptococci for Species: Group D Enterococcus?

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What is the expected reaction for the a-hemolytic and non-hemolytic streptococci for Species: Group D-S.bovis group?

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What is the expected reaction for the a-hemolytic and non-hemolytic streptococci for Species: Streptococcus pneumoniae?

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What is the expected reaction for the a-hemolytic and non-hemolytic streptococci for Species: Viridans streptococci?

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Identify B-hemolytic streptococci that are PYR negative, CAMP negative, resistant to bacitracin, and susceptible to sulfamethoxazole.

<p>Lancefield group C, F, or G</p> Signup and view all the answers

The nutritionally variant streptococci require?

<p>Vitamin B6 for growth</p> Signup and view all the answers

What has intrinsic resistance to penicillin and the aminoglycosides, shows acquired resistance to many antibiotics including vancomycin, and are nosocomial pathogens?

<p>Enterococci</p> Signup and view all the answers

Study Notes

Lancefield Classification

  • Lancefield groups categorize Streptococcus species based on specific polysaccharide antigens found in cell walls.
  • Group A Streptococcus matches with S.pyogenes, which is associated with harmful infections.
  • Group B Streptococcus corresponds to S.agalactiae, significant in neonatal infections.
  • S.equismimilis falls under Group C.
  • Non-Enterococcus categories include S.bovis group (D) and additional groups such as C, F, or G.
  • Enterococcus species like E.faecalis and E.faecium correspond to Group D.

Streptococcus Characteristics

  • Streptolysin O is an antigenic component important for serological testing.
  • Streptococcus pneumoniae colonies at 24 hours present as mucoid and alpha-hemolytic.
  • Group-specific reactions are essential for identifying beta-hemolytic streptococci:
    • S.pyogenes typically shows PYR positive and bacitracin susceptible.
    • S.agalactiae is usually CAMP positive and PYR negative.

Clinical Implications

  • Infections caused by Group A Streptococcus can lead to complications such as acute rheumatic fever or acute glomerulonephritis.
  • Enterococci have intrinsic resistance to penicillin and aminoglycosides, posing a challenge in treating infections and may show acquired resistance to other antibiotics like vancomycin.
  • Nutritionally variant streptococci require Vitamin B6 for growth, highlighting their specific nutritional needs.

Test Identification

  • For identifying beta-hemolytic streptococci, tests like bacitracin sensitivity and PYRase are crucial.
  • Distinctions between groups can guide appropriate antibiotic therapy and clinical management decisions.
  • PYR negative tests are uncommon for Enterococcus, serving as an identification marker for bacterial differentiation.

Additional Information

  • Viridans group streptococci, known for their alpha-hemolytic properties, play a role in endocarditis and are generally opportunistic pathogens.
  • The expected reactions of non-hemolytic streptococci, like the S.bovis group and Streptococcus pneumoniae, highlight their biochemical profiles for laboratory diagnosis.

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Description

This quiz focuses on Chapter 8 of Clinical Microbiology, specifically matching Lancefield groups to their corresponding species. Each card presents a different species, allowing for interactive learning and memorization of key classifications.

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