Clinical Biochemistry Lecture 3: Complex Lipids
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Questions and Answers

What is the primary function of surfactant in the lungs?

  • To decrease surface tension between water and air (correct)
  • To produce mucus in the airways
  • To increase surface tension between water and air
  • To regulate oxygen levels in the blood
  • What is the chemical composition of sphingomyelin?

  • Glycerol, phosphoric acid, and fatty acid
  • Glycerol, fatty acid, and choline
  • Sphingosine, phosphoric acid, choline, and fatty acid (correct)
  • Fatty acid, sphingosine, and galactose
  • What is the primary component of ceramide?

  • Glycerol and phosphoric acid
  • Sphingosine and fatty acid (correct)
  • Fatty acid and choline
  • Sphingosine and glycerol
  • Where are cerebrosides primarily found in the body?

    <p>In the white matter of the brain and myelin sheath of nerves</p> Signup and view all the answers

    What is the common component of all glycolipids and sphingomyelin?

    <p>Sphingosine</p> Signup and view all the answers

    What is the likely outcome for premature infants lacking sufficient surfactant?

    <p>They will have a higher risk of respiratory distress syndrome</p> Signup and view all the answers

    What is the definition of complex lipids?

    <p>Esters of fatty acids containing groups in addition to an alcohol and one or more fatty acids.</p> Signup and view all the answers

    What are phospholipids composed of?

    <p>Alcohol, fatty acid, phosphoric acid, and a nitrogenous base.</p> Signup and view all the answers

    How are phospholipids classified?

    <p>Based on the type of alcohol present.</p> Signup and view all the answers

    What type of phospholipid has glycerol as the alcohol?

    <p>Glycerophospholipids</p> Signup and view all the answers

    What is the most abundant phospholipid in membranes?

    <p>Phosphatidylcholine (lecithin)</p> Signup and view all the answers

    What is the property of phospholipids that allows them to form bimolecular layers?

    <p>Amphipathic nature</p> Signup and view all the answers

    What is the orientation of the polar group in a phospholipid bimolecular layer?

    <p>Oriented outward</p> Signup and view all the answers

    What is the function of phosphatidylcholine (lecithin) in the body?

    <p>Storage of choline</p> Signup and view all the answers

    Study Notes

    Complex Lipids

    • Compound lipids are esters of fatty acids containing groups in addition to an alcohol and one or more fatty acids.
    • Phospholipids are a type of compound lipid that contains an alcohol, fatty acid, phosphoric acid, and a nitrogenous base (choline, serine, inositol) or other alcoholic group.

    Phospholipids

    • Phospholipids are classified into two types based on the type of alcohol present:
      • Glycerophospholipids: contain glycerol as the alcohol
      • Sphingophospholipids: contain sphingosine as the alcohol

    Glycerophospholipids

    • Examples include:
      • Phosphatidyl choline (lecithin)
      • Phosphatidyl ethanolamine (cephalin)
      • Phosphatidyl serine
      • Phosphatidyl inositol
      • Cardiolipins
      • Plasmalogens

    Phosphatidyl Choline (Lecithin)

    • The most abundant phospholipid in membranes
    • Represents a large proportion of body store of choline
    • Acts as an active agent "Surfactant" that lowers surface tension
    • Contains alcohol, fatty acid, phosphoric acid, and choline
    • Major surfactant produced by certain cells within the lung, preventing alveoli from collapse by decreasing surface tension between water and air

    Sphingomyelin

    • A sphingophospholipid that does not contain glycerol but an unsaturated amino alcohol, sphingosine
    • Contains a molecule of choline, phosphoric acid, and a fatty acid
    • Makes up a large part of the myelin sheath found in nerves

    Ceramide

    • Composed of sphingosine and a fatty acid joined by an amide bond
    • Common to all glycolipids and sphingomyelin

    Glycolipids

    • Lipids containing a fatty acid, sphingosine, and carbohydrate
    • Examples include:
      • Cerebrosides: contain a molecule of fatty acid, an amino alcohol sphingosine, and a sugar (usually galactose)
      • Found in the white matter of the brain and myelin sheath of nerves

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    Description

    This quiz assesses understanding of complex lipids, including phospholipids and glycolipids, covered in Clinical Biochemistry Lecture 3 at Al-Ayen University's College of Medicine.

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