Podcast
Questions and Answers
What is the occurrence rate of cleft lip with or without cleft palate in live births?
What is the occurrence rate of cleft lip with or without cleft palate in live births?
Which statement describes a complete cleft lip?
Which statement describes a complete cleft lip?
What is the primary structure responsible for the formation of the upper lip during embryonic development?
What is the primary structure responsible for the formation of the upper lip during embryonic development?
At what gestational weeks does the critical period for lip and palate development occur?
At what gestational weeks does the critical period for lip and palate development occur?
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What type of cleft occurs when the palate fissure extends beyond the incisive foramen?
What type of cleft occurs when the palate fissure extends beyond the incisive foramen?
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What results from the incomplete fusion of the two palatal shelves?
What results from the incomplete fusion of the two palatal shelves?
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Which embryonic structures give rise to the secondary palate?
Which embryonic structures give rise to the secondary palate?
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What is the primary defect leading to the occurrence of cleft lip?
What is the primary defect leading to the occurrence of cleft lip?
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What should be avoided in infants with cleft palates due to the risk of airway obstruction?
What should be avoided in infants with cleft palates due to the risk of airway obstruction?
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Which inhalational anesthetics are considered safe for induction of anesthesia?
Which inhalational anesthetics are considered safe for induction of anesthesia?
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Which technique is NOT recommended for managing difficult endotracheal intubation in children with craniofacial syndrome?
Which technique is NOT recommended for managing difficult endotracheal intubation in children with craniofacial syndrome?
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What should be confirmed before administering neuromuscular blocking agents?
What should be confirmed before administering neuromuscular blocking agents?
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What is the purpose of using an oral pack in the surgical setting?
What is the purpose of using an oral pack in the surgical setting?
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What key factor must be managed during anesthesia maintenance?
What key factor must be managed during anesthesia maintenance?
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What should be performed after positioning the patient for surgery?
What should be performed after positioning the patient for surgery?
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What can common problems with the endotracheal tube lead to?
What can common problems with the endotracheal tube lead to?
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Which condition is NOT commonly associated with airway obstruction in patients with congenital abnormalities?
Which condition is NOT commonly associated with airway obstruction in patients with congenital abnormalities?
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What is the main anesthetic concern related to intubation in infants under 6 months of age?
What is the main anesthetic concern related to intubation in infants under 6 months of age?
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Which of the following is NOT a common preoperative evaluation for a patient with cleft palate?
Which of the following is NOT a common preoperative evaluation for a patient with cleft palate?
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What percentage of patients with congenital abnormalities might experience congenital heart disease?
What percentage of patients with congenital abnormalities might experience congenital heart disease?
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Which statement about obstructive sleep apnea syndrome in the context of anesthesia is true?
Which statement about obstructive sleep apnea syndrome in the context of anesthesia is true?
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Chronic rhinorrhea in children presenting for cleft palate closure is primarily caused by what?
Chronic rhinorrhea in children presenting for cleft palate closure is primarily caused by what?
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What complication may arise from recurrent hypoxia due to airway obstruction?
What complication may arise from recurrent hypoxia due to airway obstruction?
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What is a potential nutritional concern for patients with cleft palate?
What is a potential nutritional concern for patients with cleft palate?
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What is a spontaneous breathing technique with halothane used for?
What is a spontaneous breathing technique with halothane used for?
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Which of the following is NOT a benefit of controlled ventilation with muscle paralysis?
Which of the following is NOT a benefit of controlled ventilation with muscle paralysis?
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What is the role of adrenaline in local infiltrations?
What is the role of adrenaline in local infiltrations?
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Which opioid is noted for helping achieve smoother emergence during extubation?
Which opioid is noted for helping achieve smoother emergence during extubation?
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What is the anatomical location of the infraorbital nerve?
What is the anatomical location of the infraorbital nerve?
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What is the procedure for blocking the infraorbital nerve?
What is the procedure for blocking the infraorbital nerve?
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What is a significant risk following extubation?
What is a significant risk following extubation?
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How much adrenaline should be administered with local infiltrations in the presence of normocapnia and halothane?
How much adrenaline should be administered with local infiltrations in the presence of normocapnia and halothane?
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Study Notes
Introduction
- Cleft lip and palate are the most common craniofacial abnormalities
- Cleft lip (with or without cleft palate) occurs in 1/600 live births
- Cleft palate alone occurs in 1/2000 live births
- Cleft can involve lip, alveolus (gum), hard palate, soft palate (or a combination)
- Can be complete or incomplete
- Can be unilateral or bilateral
Anatomy
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Cleft lip (CL): Unilateral or bilateral fissure in the upper lip
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Complete CL: Extends across the entire lip and into the nostrils
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Incomplete CL: Ranges from subtle indentations to large defects with little tissue between clefts
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Cleft palate (CP): Unilateral or bilateral fissure in the soft palate, may extend to the hard palate
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Cleft palate can co-occur with cleft lip when the lip fissure extends past the incisive foramen, including the palatine suture
Embryology
- Lip and palate development occurs in the first trimester (weeks 6-9 of gestation)
- Upper lip and primary palate form from fusion of frontonasal and bilateral maxillary prominences
- Cleft lip occurs when this fusion fails on one or both sides
Clinical Problems
- Facial disfigurement and potential social isolation
- Feeding problems and abnormal speech
Anesthetic Concerns
- Majority of anesthetic morbidity related to cleft lip/palate surgery is airway related
- Difficulty with intubation
- Inadvertent extubation during procedure
- Postoperative airway obstruction
- Optimal anesthetic management depends on patient age, equipment, anesthetic drugs, and expertise
Preoperative Evaluation
- Thorough history and physical exam
- Identify associated congenital abnormalities (e.g., Pierre-Robin sequence, Goldenhar syndrome, Treacher Collins syndrome)
- Assess for congenital heart disease (occurs in 5-10% of cleft patients)
- Assess for chronic rhinorrhea (common due to reflux during feeding)
- Evaluate for obstructive sleep apnea syndrome (patients are highly sensitive to respiratory depressants in anesthetics)
Extubation
- Acute airway obstruction is a significant risk
- Surgeon should ensure the surgical field is dry
- Minimize suctioning to prevent surgical repair disruption
- Oropharyngeal airways should be avoided, if possible
- Tongue stitch may be placed in patients with pre-op airway obstruction to pull tongue away from the posterior pharyngeal wall for post-op airway support
Key Points
- Difficult laryngoscopy is a more frequent finding than a difficult airway
- Patients should be extubated when fully awake, closely monitored for airway obstruction
- Analgesia is an important part of balanced anesthetic technique
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Description
Explore the fundamental aspects of cleft lip and palate, the most common craniofacial abnormalities. This quiz covers their anatomy, occurrence rates, and embryological development. Test your knowledge on the characteristics and classifications of these conditions.