Cleft Lip and Palate Overview

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Questions and Answers

What is the occurrence rate of cleft lip with or without cleft palate in live births?

  • 1 in 600 (correct)
  • 1 in 2000
  • 1 in 1500
  • 1 in 1000

Which statement describes a complete cleft lip?

  • It extends across the whole lip and into the nostrils. (correct)
  • It is always unilateral.
  • It can only be unilateral.
  • It does not extend into the nostrils.

What is the primary structure responsible for the formation of the upper lip during embryonic development?

  • Bilateral mandible
  • Frontonasal prominence (correct)
  • Bilateral maxillary prominences (correct)
  • Lateral palatal processes

At what gestational weeks does the critical period for lip and palate development occur?

<p>Weeks 6 to 9 (A)</p> Signup and view all the answers

What type of cleft occurs when the palate fissure extends beyond the incisive foramen?

<p>Complete cleft palate (B)</p> Signup and view all the answers

What results from the incomplete fusion of the two palatal shelves?

<p>Cleft palate (C)</p> Signup and view all the answers

Which embryonic structures give rise to the secondary palate?

<p>Lateral palatal processes (C)</p> Signup and view all the answers

What is the primary defect leading to the occurrence of cleft lip?

<p>Incomplete fusion between frontonasal prominence and maxillary processes (A)</p> Signup and view all the answers

What should be avoided in infants with cleft palates due to the risk of airway obstruction?

<p>Sedative premedication (C)</p> Signup and view all the answers

Which inhalational anesthetics are considered safe for induction of anesthesia?

<p>Halothane and sevoflurane (D)</p> Signup and view all the answers

Which technique is NOT recommended for managing difficult endotracheal intubation in children with craniofacial syndrome?

<p>Standard oral intubation (D)</p> Signup and view all the answers

What should be confirmed before administering neuromuscular blocking agents?

<p>Ability to ventilate the lungs with a mask (B)</p> Signup and view all the answers

What is the purpose of using an oral pack in the surgical setting?

<p>To absorb blood and secretions (B)</p> Signup and view all the answers

What key factor must be managed during anesthesia maintenance?

<p>Controlling temperature (A)</p> Signup and view all the answers

What should be performed after positioning the patient for surgery?

<p>Checking the patency and position of the endotracheal tube (D)</p> Signup and view all the answers

What can common problems with the endotracheal tube lead to?

<p>Extubation or endobronchial intubation (C)</p> Signup and view all the answers

Which condition is NOT commonly associated with airway obstruction in patients with congenital abnormalities?

<p>Cleft Lip (A)</p> Signup and view all the answers

What is the main anesthetic concern related to intubation in infants under 6 months of age?

<p>Difficult intubation due to retrognathia (B)</p> Signup and view all the answers

Which of the following is NOT a common preoperative evaluation for a patient with cleft palate?

<p>Evaluation of speech therapy needs (C)</p> Signup and view all the answers

What percentage of patients with congenital abnormalities might experience congenital heart disease?

<p>5 - 10% (C)</p> Signup and view all the answers

Which statement about obstructive sleep apnea syndrome in the context of anesthesia is true?

<p>Patients are sensitive to respiratory depressant effects of anesthetics. (C)</p> Signup and view all the answers

Chronic rhinorrhea in children presenting for cleft palate closure is primarily caused by what?

<p>Reflux into the nose during feeds (B)</p> Signup and view all the answers

What complication may arise from recurrent hypoxia due to airway obstruction?

<p>Right ventricular hypertrophy (A)</p> Signup and view all the answers

What is a potential nutritional concern for patients with cleft palate?

<p>Nutritional anemia due to feeding difficulties (C)</p> Signup and view all the answers

What is a spontaneous breathing technique with halothane used for?

<p>To provide safety during accidental disconnection or extubation. (D)</p> Signup and view all the answers

Which of the following is NOT a benefit of controlled ventilation with muscle paralysis?

<p>Increased PaCO2 levels. (D)</p> Signup and view all the answers

What is the role of adrenaline in local infiltrations?

<p>To prolong the effects of local anesthetics. (D)</p> Signup and view all the answers

Which opioid is noted for helping achieve smoother emergence during extubation?

<p>Fentanyl. (A)</p> Signup and view all the answers

What is the anatomical location of the infraorbital nerve?

<p>Just medial to the infraorbital foramen. (D)</p> Signup and view all the answers

What is the procedure for blocking the infraorbital nerve?

<p>Insert the needle perpendicularly to the skin until bony resistance is felt. (A)</p> Signup and view all the answers

What is a significant risk following extubation?

<p>Acute airway obstruction. (C)</p> Signup and view all the answers

How much adrenaline should be administered with local infiltrations in the presence of normocapnia and halothane?

<p>5 mcg/kg. (D)</p> Signup and view all the answers

Flashcards

What is a Cleft Lip (CL)?

A split in the upper lip, sometimes extending to the nostril.

What is a Complete Cleft Lip?

A split in the upper lip that goes all the way through, reaching the nostril.

What is an Incomplete Cleft Lip?

A split in the upper lip that is not complete, meaning there is some tissue connecting the two sides.

What is a Cleft Palate (CP)?

A split in the roof of the mouth (palate), sometimes extending to the hard palate.

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What is a cleft lip?

A birth defect where the lip is split, can be either complete or incomplete.

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How does a Cleft Palate develop?

The process of a cleft palate forming during the first trimester of pregnancy.

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How does a Cleft Lip develop?

The process of a cleft lip forming during the first trimester of pregnancy.

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What is a cleft palate?

A birth defect where the palate is split, can be either complete or incomplete.

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Airway Complications

The most frequent complications associated with cleft palate surgeries involve the airway, such as difficulty intubating, accidental extubation during the procedure, and airway obstruction after surgery.

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Associated Abnormalities

Before a cleft palate surgery, it's crucial to check for any additional birth defects. These could include syndromes like Pierre-Robin Syndrome, Goldenhar Syndrome, and Treacher Collins Syndrome, or congenital heart disease.

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Chronic Rhinorrhea

A common concern in children with cleft palate is chronic rhinorrhea. This means they often experience runny noses due to food refluxing up into their nasal passages.

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Obstructive Sleep Apnea

Obstructive sleep apnea syndrome is a condition related to blocked breathing during sleep. It's important to be aware of it in cleft palate patients as they are more sensitive to the effects of anesthesia, sedatives, and painkillers.

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Right Ventricular Hypertrophy and Cor Pulmonale

Due to recurring oxygen deficiency caused by airway obstruction, some cleft palate patients may develop right ventricular hypertrophy (enlarged right ventricle) and cor pulmonale (heart problems).

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Difficult Intubation

Intubation, the placement of a breathing tube, is more challenging in children younger than 6 months with cleft palate, especially if they have retrognathia (receding lower jaw) or bilateral clefts.

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Nutrition and Hydration

Children with cleft palate may experience feeding difficulties, leading to nutritional deficiencies and anemia.

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Anesthetic Management

The successful anesthetic management for cleft palate surgery depends on the patient's age, available monitoring equipment, anesthetic drugs, and the expertise of the medical team.

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Premedication for Cleft Palate Surgery

Premedication with sedatives is not recommended for infants with cleft palates due to the increased risk of airway obstruction.

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Atropine for Cleft Palate Surgery

Atropine is used to reduce saliva production during surgery, helping to improve visibility and airway management.

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Induction of Anesthesia: Cleft Palate Surgery

Inhalational anesthesia with halothane or sevoflurane is the preferred method for inducing anesthesia in children undergoing cleft palate surgery.

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Neuromuscular Blocking Agents: Cleft Palate Surgery

Neuromuscular blocking agents are not administered until the airway can be easily managed by a mask, ensuring adequate ventilation.

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Endotracheal Intubation: Cleft Palate Challenges

Endotracheal intubation can be challenging due to the anatomical alterations in cleft palate patients. Different techniques like blind nasal intubation, fiberoptic intubation, or bougies may be necessary.

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Intubation Tube and Mouth Gag: Cleft Palate Surgery

The oral RAE tube is commonly used for cleft palate surgery and is positioned in the midline. A mouth gag helps maintain airway patency by keeping the mouth open and the tongue out of the way.

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Maintaining Airway: Cleft Palate Surgery

Maintaining a secure airway with a well-positioned endotracheal tube is crucial to avoid kinking and ensure ventilation.

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Homeostasis Monitoring: Cleft Palate Surgery

Homeostasis maintenance during surgery is important. Monitoring hypercapnia and preventing adrenaline-induced arrhythmias are key considerations.

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Spontaneous Breathing with Halothane

A breathing technique using halothane where the patient breathes spontaneously, providing safety in case of accidental disconnection or extubation, but not suitable for very young infants.

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Controlled Ventilation with Muscle Paralysis

A breathing technique where the patient's muscles are paralyzed, allowing for a lighter level of anesthesia and quicker recovery with less bleeding.

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Local Infiltrations

Local injections used to reduce bleeding, improve surgical view, and provide some pain relief during surgery.

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Adrenaline in Local Infiltrations

A drug used in local infiltrations to reduce bleeding, only used in the presence of normal carbon dioxide levels and halothane anesthesia.

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Short-Acting Opioids for Smooth Recovery

Short-acting painkillers used to ensure a smoother recovery after surgery with less crying after the breathing tube is removed.

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Bilateral Infraorbital Nerve Blocks

Nerve blocks that provide excellent pain relief before and after surgery, without causing breathing difficulties.

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Infraorbital Nerve

A nerve that branches from the trigeminal nerve and controls sensation in the upper lip, lower eyelid, and side of the nose.

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Infraorbital Nerve Block Technique

Blocking the infraorbital nerve by injecting anesthetic medication near its exit point, providing effective pain relief.

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Study Notes

Introduction

  • Cleft lip and palate are the most common craniofacial abnormalities
  • Cleft lip (with or without cleft palate) occurs in 1/600 live births
  • Cleft palate alone occurs in 1/2000 live births
  • Cleft can involve lip, alveolus (gum), hard palate, soft palate (or a combination)
  • Can be complete or incomplete
  • Can be unilateral or bilateral

Anatomy

  • Cleft lip (CL): Unilateral or bilateral fissure in the upper lip

  • Complete CL: Extends across the entire lip and into the nostrils

  • Incomplete CL: Ranges from subtle indentations to large defects with little tissue between clefts

  • Cleft palate (CP): Unilateral or bilateral fissure in the soft palate, may extend to the hard palate

  • Cleft palate can co-occur with cleft lip when the lip fissure extends past the incisive foramen, including the palatine suture

Embryology

  • Lip and palate development occurs in the first trimester (weeks 6-9 of gestation)
  • Upper lip and primary palate form from fusion of frontonasal and bilateral maxillary prominences
  • Cleft lip occurs when this fusion fails on one or both sides

Clinical Problems

  • Facial disfigurement and potential social isolation
  • Feeding problems and abnormal speech

Anesthetic Concerns

  • Majority of anesthetic morbidity related to cleft lip/palate surgery is airway related
  • Difficulty with intubation
  • Inadvertent extubation during procedure
  • Postoperative airway obstruction
  • Optimal anesthetic management depends on patient age, equipment, anesthetic drugs, and expertise

Preoperative Evaluation

  • Thorough history and physical exam
  • Identify associated congenital abnormalities (e.g., Pierre-Robin sequence, Goldenhar syndrome, Treacher Collins syndrome)
  • Assess for congenital heart disease (occurs in 5-10% of cleft patients)
  • Assess for chronic rhinorrhea (common due to reflux during feeding)
  • Evaluate for obstructive sleep apnea syndrome (patients are highly sensitive to respiratory depressants in anesthetics)

Extubation

  • Acute airway obstruction is a significant risk
  • Surgeon should ensure the surgical field is dry
  • Minimize suctioning to prevent surgical repair disruption
  • Oropharyngeal airways should be avoided, if possible
  • Tongue stitch may be placed in patients with pre-op airway obstruction to pull tongue away from the posterior pharyngeal wall for post-op airway support

Key Points

  • Difficult laryngoscopy is a more frequent finding than a difficult airway
  • Patients should be extubated when fully awake, closely monitored for airway obstruction
  • Analgesia is an important part of balanced anesthetic technique

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