5 Questions
Describe the primary pathological features of follicular bronchiolitis.
Follicular bronchiolitis is characterized by the presence of hyperplastic lymphoid follicles with germinal centers located in the walls of bronchioles.
What are the main distinguishing histological features of constrictive bronchiolitis?
Constrictive bronchiolitis is marked by the presence of concentric, obliterative fibrosis that narrows and occludes the lumen of bronchioles without significant inflammation.
What factors distinguish aspiration pneumonia from other types of pneumonia?
Aspiration pneumonia is characterized by inhaled material (e.g., gastric contents) entering the bronchial tree, leading to a mixed infection with both aerobes and anaerobes and often involving the dependent portions of the lungs.
Explain the clinical importance of identifying the type of small airways disease via imaging and histopathology.
Identifying the type of small airways disease is crucial because it guides the treatment strategy, influences prognosis, and helps in ruling out other differential diagnoses.
What are the implications of diagnosing a patient with Diffuse Panbronchiolitis (DPB)?
Diagnosing a patient with DPB implies a chronic inflammatory disorder predominantly affecting the respiratory bronchioles, characterized by the presence of diffuse, nodular shadows on imaging and mixed cellular infiltration on histology, commonly affecting East Asian populations.
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