patho thyroid 2

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Questions and Answers

Which Class III antiarrhythmic drug contains iodine and can cause hypothyroidism via excess iodine?

  • Sotalol
  • Amiodarone (correct)
  • Flecainide
  • Dofetilide

What is the name of the effect whereby amiodarone inhibits the conversion of T4 to T3?

  • Hawthorn Effect
  • Wolff-Chaikoff Effect (correct)
  • Hawthorne Effect
  • Placebo Effect

Which isotope of iodine emits radiation and competes with elemental iodine for uptake in the thyroid gland?

  • I133
  • I129
  • I125
  • I131 (correct)

What is the major regulatory protein for the availability of T4 and T3 to tissues?

<p>Thyroxine-Binding Globulin (TBG) (B)</p> Signup and view all the answers

Which hormone raises TBG levels and modifies TBG molecules, leading to a rise in total T4 levels?

<p>Estrogen (A)</p> Signup and view all the answers

What is the most common cause of mental retardation that is treatable?

<p>Iodine deficiency (C)</p> Signup and view all the answers

Which hormone, produced by the thyroid, inhibits osteoclasts and suppresses resorption of bone?

<p>Calcitonin (A)</p> Signup and view all the answers

Which condition results from childhood hypothyroidism and leads to stunted growth and mental retardation?

<p>Cretinism (D)</p> Signup and view all the answers

What does TSH (thyrotropin) released by the anterior pituitary activate in the thyroid gland?

<p>cAMP/PKA 2nd messenger system (D)</p> Signup and view all the answers

Which metabolic effect is seen in hyperthyroid patients?

<p>Weight loss (A)</p> Signup and view all the answers

Which hormone lowers serum calcium levels and inhibits osteoclasts?

<p>Calcitonin (C)</p> Signup and view all the answers

Which hormone plays a minor role in calcium handling in humans but can be used as pharmacologic therapy for hypercalcemia?

<p>Calcitonin (B)</p> Signup and view all the answers

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