patho thyroid 2
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Questions and Answers

Which Class III antiarrhythmic drug contains iodine and can cause hypothyroidism via excess iodine?

  • Sotalol
  • Amiodarone (correct)
  • Flecainide
  • Dofetilide
  • What is the name of the effect whereby amiodarone inhibits the conversion of T4 to T3?

  • Hawthorn Effect
  • Wolff-Chaikoff Effect (correct)
  • Hawthorne Effect
  • Placebo Effect
  • Which isotope of iodine emits radiation and competes with elemental iodine for uptake in the thyroid gland?

  • I133
  • I129
  • I125
  • I131 (correct)
  • What is the major regulatory protein for the availability of T4 and T3 to tissues?

    <p>Thyroxine-Binding Globulin (TBG)</p> Signup and view all the answers

    Which hormone raises TBG levels and modifies TBG molecules, leading to a rise in total T4 levels?

    <p>Estrogen</p> Signup and view all the answers

    What is the most common cause of mental retardation that is treatable?

    <p>Iodine deficiency</p> Signup and view all the answers

    Which hormone, produced by the thyroid, inhibits osteoclasts and suppresses resorption of bone?

    <p>Calcitonin</p> Signup and view all the answers

    Which condition results from childhood hypothyroidism and leads to stunted growth and mental retardation?

    <p>Cretinism</p> Signup and view all the answers

    What does TSH (thyrotropin) released by the anterior pituitary activate in the thyroid gland?

    <p>cAMP/PKA 2nd messenger system</p> Signup and view all the answers

    Which metabolic effect is seen in hyperthyroid patients?

    <p>Weight loss</p> Signup and view all the answers

    Which hormone lowers serum calcium levels and inhibits osteoclasts?

    <p>Calcitonin</p> Signup and view all the answers

    Which hormone plays a minor role in calcium handling in humans but can be used as pharmacologic therapy for hypercalcemia?

    <p>Calcitonin</p> Signup and view all the answers

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