21 Questions
Which enzyme is responsible for the conversion of succinate to fumarate in the TCA cycle?
Fumarase
Which step in glycolysis produces ATP?
Conversion of glyceraldehyde 3-phosphate to 1,3 bisphosphoglycerate
Which enzyme is involved in the conversion of acetoacetyl CoA to 3-hydroxy-3-methylglutaryl-CoA in ketone body synthesis?
HMG-CoA synthase
Which molecule serves as the central/branch point in metabolism?
Acetyl CoA
Which process involves the conversion of acetyl CoA to citrate for storage?
TCA cycle
Which enzyme is involved in converting glucose to glucose 6-phosphate in glycolysis?
(2) Glucose → Glucose 6-phosphate through Hexo/Glucokinase
Which amino acid enters the TCA cycle at a point where 2 NADH have already been produced?
Threonine
Which substance is NOT produced by the TCA cycle?
Pyruvate
What are the reduced electron carriers produced by the TCA cycle used for?
Electron transport chain (ETC) to make ATP
Which enzyme is responsible for the conversion of acetyl CoA to citrate in the TCA cycle?
Citrate synthase
During glycolysis, which step involves the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate?
Step Three
Which enzyme is involved in the formation of 3-hydroxybutyrate during ketone body synthesis?
3-hydroxybutyrate dehydrogenase
Which amino acids can be converted to glutamate and then to α-ketoglutarate for entry into the TCA cycle without the need for additional NADH production?
Arginine, Histidine, Glutamine, Proline
Which nutrient can be stored as citrate after being pulled out from the TCA cycle?
Glucose
Which enzyme is responsible for the conversion of succinyl CoA to succinate in the TCA cycle?
Succinyl CoA synthetase
Which step of glycolysis involves the production of 2 ATP?
Step Seven
Which enzyme is involved in the formation of acetoacetyl CoA during ketone body synthesis?
Acetoacetyl CoA thiolase
Which amino acids can be converted to propionyl CoA and then to succinyl CoA for entry into the TCA cycle after 2 NADH have already been produced?
Isoleucine, Valine, Methionine, Threonine
Which nutrient can be converted to pyruvate before entering the TCA cycle?
Amino acids
Which enzyme is responsible for the conversion of malate to oxaloacetate in the TCA cycle?
Malate dehydrogenase
Where do the reduced electron carriers (NADH, FADH2) from the TCA cycle go in order to generate ATP?
Electron transport chain (ETC)
Review the steps of the citric acid cycle, also known as the TCA cycle, focusing on the conversion of metabolites and the production of NADH. Test your knowledge of the integration of metabolism in this exam review material.
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