Cisplatin Hydration Protocol

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Questions and Answers

A patient requires 1 liter of hydration for every 20 mg/m² of cisplatin to prevent nephrotoxicity. If the prescribed dose is 75 mg/m², what total fluid volume should the patient receive?

  • 3.75 liters (correct)
  • 2.50 liters
  • 3.25 liters
  • 4.00 liters

A patient is prescribed cisplatin at a dose of 50 mg/m². Knowing they need 1 liter of hydration per 20 mg/m² of cisplatin, and the IV fluid is administered at 125 mL/hour, approximately how long should the infusion run?

  • 12 hours
  • 10 hours (correct)
  • 8 hours
  • 6 hours

A patient receiving cisplatin requires a hydration infusion. If the prescribed cisplatin dose is 60 mg/m² and the hydration requirement is 1 L per 20 mg/m², what is the minimum infusion rate needed to administer the total fluid volume over 6 hours?

  • 200 mL/hour
  • 300 mL/hour
  • 500 mL/hour (correct)
  • 400 mL/hour

A patient is prescribed 80 mg/m² of cisplatin. Hydration guidelines suggest 1 liter of fluid for each 20 mg/m² of cisplatin, to be infused over 8 hours. What is the appropriate infusion rate in mL/hour??

<p>500 mL/hour (A)</p> Signup and view all the answers

A patient has a BSA of 1.8 m² and a cisplatin order of 70 mg/m². If the hydration protocol requires 1 liter of fluid for every 20 mg/m² of cisplatin, what is the total fluid volume required for hydration?

<p>3.50 Liters (B)</p> Signup and view all the answers

A patient receives cisplatin 75mg/m^2 and requires 1L of hydration for each 20mg/m^2 of cisplatin. If the infusion set delivers 15 drops/mL, what is the drip rate in drops per minute to administer the fluids over 6 hours?

<p>Approximately 83 drops/minute (C)</p> Signup and view all the answers

A patient is to receive cisplatin at 60 mg/m². The protocol dictates that they receive 1 liter of normal saline for every 20 mg/m² of cisplatin. If the pharmacy prepares the normal saline in 500 mL bags, how many bags are required for the entire hydration?

<p>3 bags (B)</p> Signup and view all the answers

If a patient experiences nephrotoxicity after cisplatin administration despite receiving hydration at 1 liter per 20 mg/m², which of the following adjustments is MOST appropriate for future treatments?

<p>Reduce the cisplatin dose in subsequent cycles. (A)</p> Signup and view all the answers

A patient receiving cisplatin at 50 mg/m² needs pre-hydration, hydration during, and post-hydration. The hydration protocol is 1 liter per 20 mg/m² cisplatin. How does this volume get distributed if it is split evenly pre, during and post?

<p>0.83 L Pre, 0.83 L during, 0.84 L post (A)</p> Signup and view all the answers

A patient received cisplatin with a pre-hydration bolus of 500 mL of normal saline, followed by continuous infusion at 1 liter per 20mg/m^2. Knowing the prescribed dose of cisplatin is 40mg/m^2, what adjustment should be made to the post-hydration fluid amount so that the total (pre+during, or during+post) is the same after the cisplatin infusion?

<p>Decrease the post-hydration volume by 500 mL (C)</p> Signup and view all the answers

Flashcards

Fluid calculation formula for cisplatin

To calculate the total fluid volume, divide the prescribed cisplatin dose (mg/m²) by 20 mg/m² (since 1 liter is needed for each 20 mg/m²) and then multiply by 1 liter. Formula: Total Fluid (L) = (Cisplatin Dose (mg/m²) / 20 mg/m²) * 1 L

Fluid volume for 75 mg/m² cisplatin

The patient should receive 3.75 liters of fluid, calculated as follows: (75 mg/m² / 20 mg/m²) * 1 L = 3.75 L

Study Notes

  • Cisplatin can cause nephrotoxicity, therefore hydration is required when treating a patient with it.
  • 1 liter of hydration for each 20 mg/m² of cisplatin is required.
  • A patient prescribed 75 mg/m² of cisplatin should receive 3.75 liters of fluid.

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