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Questions and Answers
Which of the following is NOT a primary function of the circulatory system?
Which of the following is NOT a primary function of the circulatory system?
- Regulation of body temperature.
- Transport of respiratory gases like oxygen and carbon dioxide.
- Production of red blood cells. (correct)
- Distribution of nutrients, hormones, and antibodies.
What percentage of total blood volume is typically made up of plasma?
What percentage of total blood volume is typically made up of plasma?
- Approximately 90%
- Approximately 50-55% (correct)
- Approximately 45-50%
- Approximately 8%
Which of these is a characteristic of a red blood cell that enables efficient oxygen transport?
Which of these is a characteristic of a red blood cell that enables efficient oxygen transport?
- Its lack of a nucleus. (correct)
- Its relatively small size.
- Its high concentration of plasma.
- Its spherical shape.
What is the function of hemoglobin within red blood cells?
What is the function of hemoglobin within red blood cells?
Anemia is most commonly associated with a deficiency of which of the following?
Anemia is most commonly associated with a deficiency of which of the following?
Which of the following is the primary site for the formation of new blood cells?
Which of the following is the primary site for the formation of new blood cells?
What does the term 'biconcave disc' describe in the context of this text?
What does the term 'biconcave disc' describe in the context of this text?
How many red blood cells are replaced approximately every second in a healthy human?
How many red blood cells are replaced approximately every second in a healthy human?
What is a key difference between arteries and veins?
What is a key difference between arteries and veins?
Which of the following is NOT a characteristic of white blood cells (leukocytes)?
Which of the following is NOT a characteristic of white blood cells (leukocytes)?
What is the primary function of the sinoatrial (SA) node in a heart?
What is the primary function of the sinoatrial (SA) node in a heart?
Which of the following best describes the 'lub' sound of a heartbeat?
Which of the following best describes the 'lub' sound of a heartbeat?
What is the correct order of activation in the heart's conduction system?
What is the correct order of activation in the heart's conduction system?
During ventricular systole, which valves are open and which are closed?
During ventricular systole, which valves are open and which are closed?
How does the medulla oblongata in the brain regulate heart rate?
How does the medulla oblongata in the brain regulate heart rate?
Which of the following best describes the structure of capillaries?
Which of the following best describes the structure of capillaries?
Why is there a slight delay in the electrical signal passing through the AV node before ventricular contraction?
Why is there a slight delay in the electrical signal passing through the AV node before ventricular contraction?
What determines the speed and pressure of blood flow in different types of blood vessels?
What determines the speed and pressure of blood flow in different types of blood vessels?
What does it mean for cardiac muscle tissue to be myogenic?
What does it mean for cardiac muscle tissue to be myogenic?
What is the tunica intima?
What is the tunica intima?
During the beginning of the cardiac cycle, which of the following is correct?
During the beginning of the cardiac cycle, which of the following is correct?
Which of the following physiological responses would be expected during periods of intense physical exercise?
Which of the following physiological responses would be expected during periods of intense physical exercise?
Which of the following is a characteristic of veins?
Which of the following is a characteristic of veins?
What is the primary function of a shunt vessel within the circulatory system?
What is the primary function of a shunt vessel within the circulatory system?
Which condition would result in the medulla oblongata increasing the heart rate?
Which condition would result in the medulla oblongata increasing the heart rate?
How does blood flow differ between a single and double circulatory system?
How does blood flow differ between a single and double circulatory system?
What is the significance of blood pressure dropping after blood has passed through the gills in a single circulatory system?
What is the significance of blood pressure dropping after blood has passed through the gills in a single circulatory system?
Which pressure reading is taken when the heart is contracting?
Which pressure reading is taken when the heart is contracting?
Which range of blood pressure during diastole is considered normal?
Which range of blood pressure during diastole is considered normal?
Which of the following best describes the process of atherosclerosis?
Which of the following best describes the process of atherosclerosis?
What is the underlying cause of angina, often triggered by physical activity?
What is the underlying cause of angina, often triggered by physical activity?
What is the significance of a ruptured plaque in a coronary artery?
What is the significance of a ruptured plaque in a coronary artery?
How does high salt intake contribute to an increased blood pressure?
How does high salt intake contribute to an increased blood pressure?
What is the effect of nicotine on blood vessels and how does it relate to smoking?
What is the effect of nicotine on blood vessels and how does it relate to smoking?
What physiological effect do medications for hypertension typically achieve?
What physiological effect do medications for hypertension typically achieve?
What is the effect of cold temperatures on the arterioles of the skin, and why?
What is the effect of cold temperatures on the arterioles of the skin, and why?
What is the primary effect of nitroglycerin on blood vessels to treat angina?
What is the primary effect of nitroglycerin on blood vessels to treat angina?
Which of the following correctly describes the flow of blood in a double circulatory system?
Which of the following correctly describes the flow of blood in a double circulatory system?
Flashcards
What is the function of the circulatory system?
What is the function of the circulatory system?
The circulatory system is responsible for transporting essential materials throughout the body via blood or plasma. These materials include oxygen, carbon dioxide, nutrients, hormones, antibodies, waste products, and heat.
What are the main components of blood?
What are the main components of blood?
Blood makes up approximately 8% of the human body and consists of two main components: plasma (the liquid part) and cells.
What is plasma in blood?
What is plasma in blood?
Plasma is the liquid part of blood that contains dissolved substances like proteins, electrolytes, and nutrients. It also carries waste products, hormones, and gases.
What are the cellular components of blood?
What are the cellular components of blood?
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What is the function of red blood cells?
What is the function of red blood cells?
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What is hemoglobin and why is it important?
What is hemoglobin and why is it important?
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What is anemia and what causes it?
What is anemia and what causes it?
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Why do red blood cells have a biconcave disc shape?
Why do red blood cells have a biconcave disc shape?
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Cardiac muscle
Cardiac muscle
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Myogenic Contraction
Myogenic Contraction
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Sinoatrial Node (SA node)
Sinoatrial Node (SA node)
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Cardiac Impulse
Cardiac Impulse
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Systole
Systole
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Diastole
Diastole
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AV Node Delay
AV Node Delay
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Heart Sounds
Heart Sounds
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Cardiovascular Center
Cardiovascular Center
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Bundle of His and Purkinje Fibers
Bundle of His and Purkinje Fibers
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Heart Rate
Heart Rate
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Elevated Heart Rate
Elevated Heart Rate
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Cardiac Cycle
Cardiac Cycle
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Blood Circulation
Blood Circulation
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What is the accelerator nerve?
What is the accelerator nerve?
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What is the vagus nerve?
What is the vagus nerve?
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What is epinephrine?
What is epinephrine?
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What are sphincters?
What are sphincters?
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What is vasoconstriction?
What is vasoconstriction?
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What is vasodilation?
What is vasodilation?
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What is a shunt vessel?
What is a shunt vessel?
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What is systemic circulation?
What is systemic circulation?
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What is pulmonary circulation?
What is pulmonary circulation?
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What is single circulation?
What is single circulation?
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What is double circulation?
What is double circulation?
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What is blood pressure?
What is blood pressure?
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What is systolic pressure?
What is systolic pressure?
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What is diastolic pressure?
What is diastolic pressure?
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What is coronary heart disease (CHD)?
What is coronary heart disease (CHD)?
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Study Notes
Circulatory System Overview
- Function: Transports materials throughout the body using blood (plasma). This includes respiratory gases (O2 and CO2), nutrients, hormones, antibodies, waste products, and heat.
- Organs/tissues: Heart acts as the pump to propel blood.
Blood Composition
- Blood makes up about 8% of human body weight, averaging 4-5 liters in volume.
- Composed of: Plasma (50-55%) and blood cells (45-50%).
- Plasma: Liquid component, rich in proteins, dissolved solutes (like Na+, K+, Ca2+, Cl-, HCO3-), nutrients, respiratory gases, waste products, hormones, lipoproteins, and plasma proteins.
- Blood cells: Erythrocytes (RBCs), Leukocytes (WBCs), and Thrombocytes (platelets). Constantly replaced in bone marrow from multipotent stem cells.
Red Blood Cells (Erythrocytes)
- 90% of blood cells.
- 5-6 million per mm3 of blood.
- Biconcave disc shape for large surface area-to-volume ratio, aiding efficient O2 uptake and release.
- Contain hemoglobin: Protein with iron that binds O2 and CO2.
- Low RBC count or hemoglobin (anemia) reduces O2 delivery, often due to iron deficiency. Results in energy deficiency.
- 120-day lifespan, removed by liver and spleen. 2-3 million produced per second to replace.
- Lack nuclei in mature form.
White Blood Cells (Leukocytes)
- 5,000-10,000 per mm3 of blood.
- Thin cell walls.
- Crucial for immune defense.
Heart Structure and Function
- Myogenic: Heart contracts spontaneously without external nerve impulses (initiating from SA node).
- Sinoatrial (SA) node: Pacemaker, generates electrical signals to contract atria. The signal spreads to atrioventricular (AV) node.
- Atrioventricular (AV) node: Delays the signal to allow atria to contract and fill ventricles fully before ventricles contract.
- Bundle of His and Purkinje fibers: Conduct the signal for ventricular contraction.
- Cardiac cycle: Systole (contraction) and diastole (relaxation). Contractions result in blood pumping to lungs and body. AV valves close during ventricular systole and semilunar valves open to allow blood flow to arteries. AV valves open during ventricular diastole, and semilunar valves close.
- Heart sounds (lub-dub): Closing of AV and semilunar valves.
Heart Rate Control
- Medulla oblongata regulates heart rate in response to body conditions (blood pressure, O2, pH).
- Hormones (like epinephrine) also affect heart rate.
- Sphincters regulate blood flow to different areas as needed.
Circulation Types
- Mammals: Double circulation (blood passes through the heart twice in a complete circuit).
- Fish: Single circulation (blood passes through the heart once). Slower delivery due to the low blood pressure.
Blood Pressure
- Measurement of force against artery walls, typically using a sphygmomanometer.
- Systolic pressure: During heart contraction.
- Diastolic pressure: During heart relaxation.
Coronary Heart Disease (CHD)
- Atheroma (plaque): Fatty deposits.
- Atherosclerosis: Development of atheroma. Damages artery walls due to the deposition of calcium.
- Plaque rupture: leads to clot formation, reducing blood flow to the heart, possibly leading to angina or heart attack.
- Myocardial infarction: Heart tissue damage due to oxygen deprivation.
Risk Factors for CHD
- Hypertension: Chronic high blood pressure (high salt intake, smoking, or genetics).
- Diet: High saturated fat, cholesterol.
- Obesity.
- Alcohol consumption.
- Sedentary lifestyle.
- Genetic factors.
- Age.
Artery and vein features
Arteries: thick walls, narrow lumens, corrugated inner surface, and abundant fibers Veins: thin walls, wide lumens, no inner surface corrugation, few fibers
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