Circulatory System and Lymphatic Function Quiz
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Questions and Answers

What is the primary function of elastic arteries?

  • Maintaining blood pressure during diastole (correct)
  • Connecting arterioles to capillaries
  • Regulating blood flow to specific organs
  • Facilitating nutrient exchange with tissues

Which statement accurately describes arterioles?

  • They have thick walls with elastic fibers.
  • They contain multiple layers of smooth muscle.
  • They connect directly to capillaries.
  • They are involved in the adjustment of blood flow to organs. (correct)

Which of the following structures lacks a typical capillary network?

  • Brachial artery
  • Cornea (correct)
  • Muscular arteries
  • Metarterioles

What distinguishes muscular arteries from elastic arteries?

<p>Muscular arteries adjust blood flow while elastic arteries do not. (A)</p> Signup and view all the answers

What primarily affects peripheral resistance in blood vessels?

<p>Viscosity of blood, vessel length, and vessel radius (D)</p> Signup and view all the answers

What is a critical function of venous valves in the circulatory system?

<p>Preventing backflow of blood in veins (D)</p> Signup and view all the answers

Which of the following correctly describes the structure of veins?

<p>Three layers with a thinner wall compared to arteries (B)</p> Signup and view all the answers

Which condition is commonly associated with veins?

<p>Varicosities (D)</p> Signup and view all the answers

What mechanism assists with blood flow back to the heart from veins?

<p>Muscle contractions and pressure variations (B)</p> Signup and view all the answers

How do veins differ from arteries in terms of their capacity and structure?

<p>Larger lumen and thinner walls (B)</p> Signup and view all the answers

What is the primary function of the bone marrow in relation to lymphocytes?

<p>Site of hematopoiesis and B-lymphocyte development (A)</p> Signup and view all the answers

What process in the thymus eliminates T-cells that recognize self-antigens?

<p>Negative selection (B)</p> Signup and view all the answers

At what stage of life is the thymus most active?

<p>Childhood (C)</p> Signup and view all the answers

Which of the following describes the involution of the thymus?

<p>It shrinks and decreases in size as a person ages. (A)</p> Signup and view all the answers

What structure within the thymus is associated with epithelial cells?

<p>Hassall's corpuscles (B)</p> Signup and view all the answers

What does Virchow's triad include as factors leading to thrombosis?

<p>Changes in the blood clotting system (A), Change in blood flow (C)</p> Signup and view all the answers

What is the primary function of the heart's portal system?

<p>To deliver absorbed substances directly to the liver (C)</p> Signup and view all the answers

Which of the following describes an anastomosis?

<p>Connection of blood vessels (A)</p> Signup and view all the answers

What differentiates the systemic circulation from the pulmonary circulation?

<p>Pulmonary circulation has higher pressure than systemic circulation (B)</p> Signup and view all the answers

During which phase do both atria and ventricles contract simultaneously?

<p>Systole (D)</p> Signup and view all the answers

What is the primary role of the thoracic duct?

<p>Empties lymph into the left venous angle (D)</p> Signup and view all the answers

Which lymphatic structures contribute to lymph drainage from the right side of the body?

<p>Right jugular trunk, right thoracic trunk, right bronchomediastinal trunk (D)</p> Signup and view all the answers

How is lymph flow primarily driven through the lymphatic system?

<p>Muscle contractions and thoracic pressure changes (C)</p> Signup and view all the answers

What defines high endothelial venules (HEV)?

<p>The primary sites for lymphocyte entry into lymphatic organs (C)</p> Signup and view all the answers

Which of the following describes the function of secondary lymph nodes?

<p>They allow T and B cells to interact with specific antigens. (D)</p> Signup and view all the answers

What is the role of sympathetic nerves in vasomotor regulation?

<p>They lead to vasoconstriction with increased activity. (A)</p> Signup and view all the answers

Which factors contribute to vasomotor activity besides the nervous system?

<p>Local factors and hormones like catecholamines. (A)</p> Signup and view all the answers

What is the effect of ACE inhibitors on blood pressure?

<p>They inhibit the conversion of angiotensin I to angiotensin II. (C)</p> Signup and view all the answers

What is the primary location of maximal activity for chemoreceptors involved in vasomotor regulation?

<p>At the branching of the common carotid artery. (C)</p> Signup and view all the answers

How do calcium channel blockers influence vasomotor activity?

<p>They limit the contraction capabilities of blood vessels. (B)</p> Signup and view all the answers

What is the primary function of the ductus venosus in fetal circulation?

<p>To connect the umbilical vein to the inferior vena cava (C)</p> Signup and view all the answers

Which of the following structures allows blood to bypass the fetal lungs?

<p>Foramen ovale (C), Ductus arteriosus (D)</p> Signup and view all the answers

Which layer of a blood vessel contains smooth muscle cells?

<p>Tunica media (D)</p> Signup and view all the answers

What is the role of the umbilical arteries in fetal circulation?

<p>Carrying deoxygenated blood from the fetus to the placenta (A)</p> Signup and view all the answers

In fetal circulation, what is the purpose of the foramen ovale?

<p>To allow blood to flow directly from the right atrium to the left atrium (A)</p> Signup and view all the answers

What is the primary characteristic of the tunica externa layer in blood vessels?

<p>It is rich in elastic fibers and collagenous tissues (C)</p> Signup and view all the answers

Which of the following correctly describes the hepatic propria?

<p>It's the section of the hepatic artery supplying the liver (C)</p> Signup and view all the answers

What function do pulmonary vessels serve in the circulatory system?

<p>They facilitate gas exchange in the lungs (C)</p> Signup and view all the answers

What is the role of B-lymphoblasts in the primary follicle?

<p>They result from B-cells interacting with antigens. (B)</p> Signup and view all the answers

Which component of the secondary follicle is responsible for antibody production?

<p>Plasma cells (B)</p> Signup and view all the answers

What feature distinguishes a secondary follicle from a primary follicle?

<p>Formation of germinal centers (A)</p> Signup and view all the answers

What does the term 'tunica intima' refer to?

<p>Inner layer involved in selective absorption (B)</p> Signup and view all the answers

Which of the following best describes the relationship between arteries and veins in the lymphatic system?

<p>Arteries deliver blood to organs while veins return it. (A)</p> Signup and view all the answers

What does the term 'noduli lymphoidei agregati' refer to in the context of secondary follicles?

<p>Aggregated lymphoid nodules (A)</p> Signup and view all the answers

What is the significance of the portal system in the body?

<p>It involves a double capillary network. (C)</p> Signup and view all the answers

How does the structure of the tunica media contribute to blood vessel function?

<p>It provides vascular tension. (B)</p> Signup and view all the answers

What is the main role of lymphatic vessels in the body?

<p>Return interstitial fluid to the circulatory system (B)</p> Signup and view all the answers

Which of the following structures is primarily responsible for collecting lymph from specific regions of the body?

<p>Lymphatic trunks (D)</p> Signup and view all the answers

What structural characteristic distinguishes lymphatic vessels from lymphatic capillaries?

<p>Presence of valves to prevent backflow (B)</p> Signup and view all the answers

Which lymphatic duct receives lymph from most of the body?

<p>Thoracic duct (B)</p> Signup and view all the answers

What type of lymphatic structure has thin walls, is porous, and lacks pericytes?

<p>Lymphatic capillaries (D)</p> Signup and view all the answers

Which lymphatic trunk is specifically responsible for collecting lymph from the lower limbs and pelvis?

<p>Truncus lumbalis (A)</p> Signup and view all the answers

What is the function of lymphangion in lymphatic vessels?

<p>Act as a functional unit containing valves (B)</p> Signup and view all the answers

What characteristic of lymphatic capillaries allows interstitial fluid to enter easily?

<p>Thinner walls and porous nature (A)</p> Signup and view all the answers

Which type of lymphatic structure is similar in structure to veins and possesses valves?

<p>Lymphatic vessels (C)</p> Signup and view all the answers

What defines a characteristic feature of lymphatic vessels compared to veins?

<p>Wider lumen (C)</p> Signup and view all the answers

Which type of capillary is characterized by tight junctions between endothelial cells and is least permeable?

<p>Continuous capillaries (C)</p> Signup and view all the answers

In which type of capillary would you expect to find large fenestrations allowing for the passage of large molecules?

<p>Sinusoidal capillaries (A)</p> Signup and view all the answers

What regulates blood flow through capillaries in the body?

<p>Precapillary sphincters (D)</p> Signup and view all the answers

What is the primary function of capillaries in the circulatory system?

<p>Facilitate exchange of materials between blood and tissues (C)</p> Signup and view all the answers

Which substances pass through capillary walls most easily via simple diffusion?

<p>Lipid-soluble substances (D)</p> Signup and view all the answers

What role do sinusoidal capillaries primarily serve in the body?

<p>Immune response facilitation (C)</p> Signup and view all the answers

Which function of capillaries aids in transporting immune cells to sites of infection?

<p>Passage of immune cells (A)</p> Signup and view all the answers

Which feature of the blood-brain barrier contributes to its protective role in the brain?

<p>Tightly regulated capillaries (C)</p> Signup and view all the answers

Flashcards

Elastic arteries

Large arteries with thick walls rich in elastic fibers, like the aorta. They help maintain blood pressure during diastole, ensuring continuous blood flow.

Muscular arteries

Medium-sized arteries with more smooth muscle, allowing them to regulate blood flow to specific organs.

Arterioles

Tiny arteries with one or two layers of smooth muscle, directly responsible for regulating blood flow into capillaries.

Metarterioles

Short vessels connecting arterioles to capillaries, featuring discontinuous smooth muscle, aiding in regulating blood flow to individual capillaries.

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Capillaries

Thin-walled vessels where gas and nutrient exchange happens between blood and tissues. Made of a single layer of endothelial cells.

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Systole

The contraction phase of the heart, where the heart muscle squeezes and pumps out blood.

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Diastole

The relaxation phase of the heart, where the heart muscle relaxes and fills with blood.

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Portal System

A network of blood vessels that connects two capillary beds, allowing blood to pass through two capillary systems before returning to the heart.

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Anastomosis

A connection between two blood vessels, creating an alternative pathway for blood flow.

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Terminal Artery

An artery that supplies a specific area without any other arterial supply, making it a vital connection for blood flow. If blocked, it can lead to tissue damage.

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Bone Marrow

The primary lymphoid organ where hematopoiesis occurs, generating various blood cells, including the precursors of T and B lymphocytes. B lymphocytes complete their development here, becoming immunocompetent.

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Thymus

The primary lymphoid organ responsible for T-lymphocyte maturation, where they learn to recognize foreign antigens and develop their immune functions.

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Positive Selection

A process during T-cell development in the thymus where T cells that recognize self MHC molecules are eliminated, preventing autoimmune attacks. This ensures the immune system doesn't attack its own body.

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Negative Selection

A process during T-cell development in the thymus where T cells that bind to MHC molecules presenting self antigens are eliminated, preventing autoimmune reactions. This further ensures the immune system is tolerant of the body's own cells.

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Thymus Involution

A phenomenon where the thymus gradually shrinks with age, leading to reduced T-cell production. This is a natural process, and its size is inversely proportional to the individual's age.

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Vein structure

Veins have three layers (intima, media, externa), though the arrangement varies depending on their location. The muscular layer is more prominent in veins in the lower body, which helps with blood flow.

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What are veins?

A vein is a blood vessel that carries deoxygenated blood back to the heart. They have thinner walls and a larger lumen than arteries.

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Venous valves

About 80% of veins have valves. These are like tiny doors that prevent blood from flowing backwards. They are crucial for returning blood to the heart.

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Common venous conditions

Varicosities are irregular and enlarged veins. DVT is a deep vein thrombosis, a blood clot in a deep vein, usually in the leg. Thrombophlebitis is a blood clot that causes inflammation in a vein.

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How does blood flow back to the heart from veins?

Veins use muscle contractions, anastomatic connections (connections between veins), and the pumping action of the heart to help blood flow back to the heart.

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What is the Thoracic Duct?

The largest lymphatic vessel in the body, carrying lymph from the lower body, abdomen, and left side of the chest. It starts under the cisterna chyli and empties into the left venous angle, where it joins the subclavian and jugular veins.

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What is the Lymphatic Duct?

A smaller lymphatic vessel that drains lymph mainly from the right upper body, including the right arm, head, and neck. It empties into the right venous angle, where it joins the subclavian and jugular veins.

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What are Secondary Lymph Nodes?

Collections of lymphatic tissue, primarily in the mucous membranes of the digestive, respiratory, and urinary tracts. They contain mature but naive T and B lymphocytes, which can encounter and respond to specific antigens.

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What are High Endothelial Venules (HEV)?

Specialized vessels within lymphatic organs that allow lymphocytes to leave the blood vessels and enter the lymphatic tissue to encounter antigens. They have special adhesion molecules that help lymphocytes to cross the vessel wall.

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What is Lymphedema?

A condition where lymph drainage is impaired due to malfunctioning lymphatic vessels. This can lead to swelling in the affected area, commonly in the arms or legs.

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What is Vasomotorika?

Vasomotorika is the dynamic regulation of blood vessel diameter, a crucial action controlled by the nervous system and local factors.

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How do sympathetic nerves control blood vessels?

Sympathetic nerve activity is like a switch: Increased activity constricts blood vessels, while decreased activity causes dilation.

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What roles do pressoreceptors and chemoreceptors play in Vasomotorika?

Pressoreceptors sense vessel stretching, providing feedback to the brain about blood pressure, while chemoreceptors monitor O₂ and CO₂ levels.

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How do ACE inhibitors act in hypertension?

ACE inhibitors block the conversion of angiotensin I to angiotensin II, reducing blood pressure.

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How do adrenergic receptor blockers work?

Adrenergic receptor blockers reduce the effects of the sympathetic nervous system, hindering vasoconstriction.

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Umbilical vein

The umbilical vein carries oxygenated blood from the placenta to the fetus.

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Ductus venosus

The ductus venosus is a blood vessel that connects the umbilical vein to the inferior vena cava, allowing oxygenated blood to bypass the fetal liver.

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Foramen ovale

The foramen ovale is an opening between the right and left atria of the fetal heart, allowing blood to flow directly from the right atrium to the left atrium, bypassing the fetal lungs.

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Ductus arteriosus

The ductus arteriosus is a blood vessel that connects the pulmonary artery to the aorta, diverting most of the blood away from the fetal lungs.

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Tunica externa

The tunica externa is the outermost layer of a blood vessel, composed of elastic fibers and collagenous tissue. It helps to anchor the vessel to surrounding structures.

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Tunica media

The tunica media is the middle layer of a blood vessel, composed of smooth muscle cells. This layer helps regulate blood vessel diameter and blood flow.

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Tunica intima

The tunica intima is the innermost layer of a blood vessel, composed of endothelial cells. It provides a smooth lining that minimizes friction as blood flows through the vessel.

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Pulmonary arteries

The pulmonary arteries carry deoxygenated blood from the right ventricle of the heart to the lungs for gas exchange.

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What is the Zametno središte?

A dark, generating center within the follicle, formed from B-lymphoblasts. It's crucial for B-cell proliferation and differentiation.

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What is the Zona omotača?

A layer surrounding the germinal center, it plays a role in B-cell development.

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What is a secondary follicle?

Contains a germinal center (darker staining) and a mantle zone (lighter staining), a key site of B-cell activity.

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What are T-lymphocyte follicles?

Present in secondary follicles, they interact with B lymphocytes, assisting in immune responses.

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What are Noduli lymphoidei agregati?

Aggregated lymphoid nodules, located within lymphoid organs, and contribute to immune system function.

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What is the arterial/venous flow in lymphatic system?

Describes the flow of blood within the lymphatic system. Arteries are efferent (carrying blood away), and veins are afferent (carrying blood towards).

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What is the tunica media in blood vessels?

The middle layer of blood vessel walls, important for maintaining blood vessel construction and vascular tension.

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What is the tunica intima in blood vessels?

The innermost layer of blood vessel walls, crucial for filtering and absorbing materials in the blood.

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What are lymphatic vessels?

Lymphatic vessels are a network of tubes that collect interstitial fluid (fluid between cells) and return it to the bloodstream. They also transport fats from the digestive system.

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What are lymphatic capillaries?

Lymphatic capillaries are the smallest lymphatic vessels. They have thin walls and are permeable to large molecules, allowing them to collect fluid, immune cells, and pathogens from tissues.

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What are lymphatic vessels?

Lymphatic vessels are larger than lymphatic capillaries and have valves to prevent backflow. They transport lymph, the fluid collected by the lymphatic system.

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What are lymphatic trunks?

Lymphatic trunks are large vessels that collect lymph from specific regions of the body. There are five main trunks: lumbar, intestinal, bronchomediastinal, subclavian, and jugular.

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What are lymphatic ducts?

Lymphatic ducts are the largest lymphatic vessels in the body. They receive lymph from the trunks and empty into the venous system. There are two main ducts: the thoracic duct and the right lymphatic duct.

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What is a lymphangion?

Lymphangion is a functional unit of a lymphatic vessel. It's like a segment of a vein containing valves to prevent backflow.

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What is lymph?

Lymph is the fluid collected by the lymphatic system. It contains interstitial fluid, immune cells, and sometimes pathogens.

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What is kilus?

Kilus is a milky lymph rich in fats, typically from the digestive system. It's transported by the lymphatic system and eventually enters the bloodstream.

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What is the role of the lymphatic system in immunity?

The lymphatic system plays a crucial role in the body's defense against pathogens. It transports immune cells to infected areas and helps to filter out harmful substances.

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How is the lymphatic system connected to the circulatory system?

The lymphatic system is closely associated with the circulatory system. Lymphatic vessels drain excess fluid from the tissues and return it to the bloodstream.

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Continuous Capillaries

These capillaries have tight junctions between their endothelial cells, resulting in the lowest permeability, allowing only small molecules to pass through. They are found in most tissues.

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Fenestrated Capillaries

These capillaries have 'windows' or pores in their endothelial cells, making them more permeable than continuous capillaries. This enables them to facilitate rapid absorption or secretion, as found in the intestinal villi and endocrine glands.

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Sinusoidal Capillaries

These capillaries have large fenestrations and an incomplete basal lamina, making them the most permeable type. They allow the passage of even large molecules, contributing to their role in crucial organs like the liver, bone marrow, and lymphoid organs.

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Exchange of materials

The exchange of nutrients, gases, and waste products between blood and surrounding tissues is a primary function of capillaries. This vital exchange ensures proper cellular functioning throughout the body.

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Regulation of blood flow

Capillaries play a crucial role in regulating blood flow to different parts of the body. Factors like precapillary sphincters, which are tiny muscles surrounding capillaries, regulate blood flow.

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Immune function

Capillaries facilitate the movement of immune cells, especially white blood cells, from the blood to the sites of infection or injury. This enables the immune system to respond effectively to threats.

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Blood-Brain Barrier

The capillaries in the brain are tightly regulated to protect the central nervous system from harmful substances. This selective barrier is crucial for brain function.

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Transport mechanisms

Lipid-soluble substances like oxygen and carbon dioxide can pass through easily via simple diffusion, while water-soluble substances require pores to move across the capillary walls.

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Study Notes

Arteries

  • Arteries carry oxygenated blood away from the heart.
  • They have a thick, strong, elastic wall (tunica media) to withstand high blood pressure.
  • The three layers (tunics) of the artery wall are the tunica intima, tunica media, and tunica externa.
  • Arterioles are smaller branches of arteries, that control the blood flow into the capillaries.
  • They constrict or dilate to regulate blood pressure and flow.

Veins

  • Veins carry deoxygenated blood back to the heart.
  • They have thinner walls than arteries, with less elastic tissue.
  • Veins have valves to prevent blood from flowing backward against gravity.
  • The three layers (tunics) of the vein wall are tunica intima, tunica media, and tunica externa.
  • Venules are small vessels that connect capillaries to veins.

Capillaries

  • Capillaries connect arterioles to venules.
  • They are very small and thin-walled; single layer of endothelium.
  • This thinness allows for the exchange of oxygen, nutrients, and waste products between blood and tissues.
  • They form a vast network throughout the body, allowing extensive contact with body tissues.
  • The endothelial cell lining of capillary walls is very thin, allowing for rapid exchange of materials between the blood and the interstitial fluid.
  • Capillaries are important for gas exchange (O2 and CO2), and nutrient and waste exchange.
  • The permeability differs in different tissue types, with brain capillaries being highly selective (blood-brain barrier).

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Test your knowledge on the key aspects of the circulatory and lymphatic systems, including the functions of arteries, veins, and lymphocyte production in the bone marrow. Questions cover the structure and roles of various components within these systems, as well as the mechanisms that maintain blood flow and immune function.

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