Questions and Answers
What is the brand name of Cinacalcet?
What is the generic name of Sensipar?
What class of drug is Cinacalcet/Sensipar?
Calcimimetics
What is the mechanism of action (MOA) of Cinacalcet/Sensipar?
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What are the indications for using Cinacalcet/Sensipar?
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What is a contraindication for Cinacalcet/Sensipar?
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What are potential adverse reactions of Cinacalcet/Sensipar?
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What precaution should be considered when using Cinacalcet/Sensipar?
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What is a noted drug interaction with Cinacalcet/Sensipar?
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The common doses for Cinacalcet/Sensipar are ______ mg.
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Study Notes
Cinacalcet/Sensipar Overview
- Cinacalcet is marketed under the brand name Sensipar.
- It belongs to the drug class of calcimimetics.
Mechanism of Action (MOA)
- Enhances sensitivity of parathyroid gland chief cell calcium-sensing receptors.
- Results in decreased secretion of parathyroid hormone (PTH).
Indications for Use
- Treats secondary hyperparathyroidism in patients with chronic kidney disease on dialysis.
- Used for hypercalcemia associated with primary hyperparathyroidism and for parathyroid carcinoma.
Contraindications
- Should not be used in patients with hypocalcemia.
Adverse Reactions
- Common adverse effects include hypocalcemia and hypoparathyroidism.
- May lead to QT prolongation and increase risk of ventricular arrhythmias.
Precautions
- Caution is advised in patients with QT syndrome or existing QT prolongation.
Drug Interactions
- Has known interactions with eliglustat, which can lead to increased serum levels.
Dosage and Administration
- Available in dosages of 30 mg, 60 mg, and 90 mg for administration.
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Description
Test your knowledge of Cinacalcet, also known as Sensipar, through these flashcards. Explore its drug classification, mechanism of action, and important details. Ideal for students and healthcare professionals looking to refresh their understanding of this calcimimetic agent.
