Chronic Pyelonephritis and Xanthogranulomatous Pyelonephritis
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Questions and Answers

What is the term used for renal pathology associated with sclerosis of renal arterioles and small arteries?

  • Hyalinization
  • Nephrosclerosis (correct)
  • Glomerulosclerosis
  • Medial thickening
  • What contributes to the narrowing of vessels affected by nephrosclerosis?

  • Genetic defects
  • Extravasation of plasma proteins (correct)
  • Aging
  • Increased blood flow
  • What does ischemia in nephrosclerosis lead to?

  • Medial thickening
  • Glomerulosclerosis (correct)
  • Chronic tubulointerstitial injury
  • Increased blood flow
  • What does the fine, leathery granularity on the cortical surface illustrate in benign nephrosclerosis?

    <p>Increased deposition of basement membrane matrix</p> Signup and view all the answers

    What are the clinical hallmarks that distinguish tubulointerstitial disorders from glomerular diseases?

    <p>Impaired ability to concentrate urine</p> Signup and view all the answers

    What characterizes acute pyelonephritis?

    <p>Associated with urinary tract infection</p> Signup and view all the answers

    What is a dominant factor in causing chronic pyelonephritis?

    <p>Bacterial infection</p> Signup and view all the answers

    How is tubulointerstitial nephritis distinguished from glomerular diseases?

    <p>Presence of defects in tubular function</p> Signup and view all the answers

    Which type of kidney inflammation is characterized by the accumulation of foamy macrophages, plasma cells, lymphocytes, and polymorphonuclear cells?

    <p>Xanthogranulomatous pyelonephritis</p> Signup and view all the answers

    What is a rare form of chronic pyelonephritis that is associated with Proteus infection and obstruction?

    <p>Xanthogranulomatous pyelonephritis</p> Signup and view all the answers

    In which type of kidney inflammation may tubulitis be common, and interstitial non-necrotizing granulomas may be seen when tubules rupture?

    <p>Xanthogranulomatous pyelonephritis</p> Signup and view all the answers

    Which kidney condition may produce large and yellowish-orange nodules that can be grossly confused with renal cell carcinoma?

    <p>Xanthogranulomatous pyelonephritis</p> Signup and view all the answers

    Which of the following is NOT a common cause of nephrotoxic acute tubular injury (ATI) according to the text?

    <p>Inadequate blood flow accompanied by shock</p> Signup and view all the answers

    What can result in characteristic intratubular hemoglobin or myoglobin casts in cases of ischemic and nephrotoxic ATI?

    <p>Skeletal muscle injuries</p> Signup and view all the answers

    What contributes to the reversibility of acute tubular injury (ATI) according to the text?

    <p>Patchiness of tubular necrosis</p> Signup and view all the answers

    Which cells are particularly sensitive to ischemia and vulnerable to toxins in the context of acute tubular injury?

    <p>Proximal tubular epithelial cells</p> Signup and view all the answers

    What structural alteration occurs as a result of ischemia in tubular epithelial cells?

    <p>Single cell drop-out and necrosis</p> Signup and view all the answers

    What can be observed in the tubules in cases of acute tubular injury based on the description provided?

    <p>Low epithelial lining and cellular debris in the lumen</p> Signup and view all the answers

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