Chronic Pyelonephritis and Xanthogranulomatous Pyelonephritis
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Questions and Answers

What is the term used for renal pathology associated with sclerosis of renal arterioles and small arteries?

  • Hyalinization
  • Nephrosclerosis (correct)
  • Glomerulosclerosis
  • Medial thickening

What contributes to the narrowing of vessels affected by nephrosclerosis?

  • Genetic defects
  • Extravasation of plasma proteins (correct)
  • Aging
  • Increased blood flow

What does ischemia in nephrosclerosis lead to?

  • Medial thickening
  • Glomerulosclerosis (correct)
  • Chronic tubulointerstitial injury
  • Increased blood flow

What does the fine, leathery granularity on the cortical surface illustrate in benign nephrosclerosis?

<p>Increased deposition of basement membrane matrix (B)</p> Signup and view all the answers

What are the clinical hallmarks that distinguish tubulointerstitial disorders from glomerular diseases?

<p>Impaired ability to concentrate urine (C)</p> Signup and view all the answers

What characterizes acute pyelonephritis?

<p>Associated with urinary tract infection (B)</p> Signup and view all the answers

What is a dominant factor in causing chronic pyelonephritis?

<p>Bacterial infection (B)</p> Signup and view all the answers

How is tubulointerstitial nephritis distinguished from glomerular diseases?

<p>Presence of defects in tubular function (B)</p> Signup and view all the answers

Which type of kidney inflammation is characterized by the accumulation of foamy macrophages, plasma cells, lymphocytes, and polymorphonuclear cells?

<p>Xanthogranulomatous pyelonephritis (B)</p> Signup and view all the answers

What is a rare form of chronic pyelonephritis that is associated with Proteus infection and obstruction?

<p>Xanthogranulomatous pyelonephritis (D)</p> Signup and view all the answers

In which type of kidney inflammation may tubulitis be common, and interstitial non-necrotizing granulomas may be seen when tubules rupture?

<p>Xanthogranulomatous pyelonephritis (D)</p> Signup and view all the answers

Which kidney condition may produce large and yellowish-orange nodules that can be grossly confused with renal cell carcinoma?

<p>Xanthogranulomatous pyelonephritis (D)</p> Signup and view all the answers

Which of the following is NOT a common cause of nephrotoxic acute tubular injury (ATI) according to the text?

<p>Inadequate blood flow accompanied by shock (C)</p> Signup and view all the answers

What can result in characteristic intratubular hemoglobin or myoglobin casts in cases of ischemic and nephrotoxic ATI?

<p>Skeletal muscle injuries (A)</p> Signup and view all the answers

What contributes to the reversibility of acute tubular injury (ATI) according to the text?

<p>Patchiness of tubular necrosis (B)</p> Signup and view all the answers

Which cells are particularly sensitive to ischemia and vulnerable to toxins in the context of acute tubular injury?

<p>Proximal tubular epithelial cells (D)</p> Signup and view all the answers

What structural alteration occurs as a result of ischemia in tubular epithelial cells?

<p>Single cell drop-out and necrosis (B)</p> Signup and view all the answers

What can be observed in the tubules in cases of acute tubular injury based on the description provided?

<p>Low epithelial lining and cellular debris in the lumen (C)</p> Signup and view all the answers

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