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Chronic Obstructive Lung Disease (COPD) in Older Adults
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Chronic Obstructive Lung Disease (COPD) in Older Adults

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Questions and Answers

What is the primary limitation of using lung function to adjust treatment in asthma patients?

  • Lack of correlation between FEV1 and symptoms
  • Inability to measure FEV1 accurately
  • Unavailability of lung function tests in clinics
  • Between-visit variability of FEV1 (correct)
  • How is asthma severity typically assessed?

  • Using a combination of FEV1 and symptoms
  • Prospectively based on symptoms and exacerbations
  • Retrospectively from the level of treatment required to control symptoms and exacerbations (correct)
  • Based on the degree of airflow limitation
  • What is the recommended frequency of lung function measurement for most adults?

  • Every 5 years
  • Every 1-2 years (correct)
  • Every 3-6 months
  • Only at diagnosis
  • What is the significance of low FEV1 in asthma patients?

    <p>It is an independent predictor of exacerbation risk</p> Signup and view all the answers

    Which of the following patients may benefit from long-term PEF monitoring?

    <p>Patients with severe asthma or impaired perception of airflow limitation</p> Signup and view all the answers

    Why may some asthma patients have few symptoms despite having low FEV1?

    <p>They have poor perception of airflow limitation</p> Signup and view all the answers

    What percentage of total healthcare expenditures is expected to be spent on asthma in developed economies?

    <p>1-2%</p> Signup and view all the answers

    What is the main cause of death in older adults, according to the provided information?

    <p>COPD</p> Signup and view all the answers

    What is the estimated number of individuals affected by asthma worldwide?

    <p>300 million</p> Signup and view all the answers

    What is the primary pharmacologic treatment for COPD?

    <p>Inhaled bronchodilators and steroids</p> Signup and view all the answers

    What is the effect of smoking cessation on lung function?

    <p>It slows the decline in lung function</p> Signup and view all the answers

    What is the prevalence of asthma in people ≥65 years?

    <p>5%–10%</p> Signup and view all the answers

    What is the effect of age on forced vital capacity, FEV1, and PaO2?

    <p>They decrease with age</p> Signup and view all the answers

    What is a significant consequence of asthma?

    <p>School and work absence</p> Signup and view all the answers

    What is the primary focus of STEP 1 in the stepwise approach to control asthma symptoms and reduce risk?

    <p>Diagnosis</p> Signup and view all the answers

    Which of the following is NOT a consideration in the stepwise approach to control asthma symptoms and reduce risk?

    <p>Allergen immunotherapy</p> Signup and view all the answers

    What is the main goal of STEP 2 in the stepwise approach to control asthma symptoms and reduce risk?

    <p>To adjust the controller choice based on patient preference</p> Signup and view all the answers

    Which step in the stepwise approach involves referring patients for add-on treatment?

    <p>STEP 5</p> Signup and view all the answers

    What is the primary focus of STEP 3 in the stepwise approach to control asthma symptoms and reduce risk?

    <p>Treat modifiable risk factors</p> Signup and view all the answers

    Which of the following is a consideration in STEP 4 of the stepwise approach to control asthma symptoms and reduce risk?

    <p>Medication side-effects</p> Signup and view all the answers

    What is the primary goal of the stepwise approach to control asthma symptoms and reduce risk?

    <p>To control symptoms and reduce risk</p> Signup and view all the answers

    Which step in the stepwise approach involves assessing inhaler technique and adherence?

    <p>STEP 2</p> Signup and view all the answers

    What is the primary focus of STEP 5 in the stepwise approach to control asthma symptoms and reduce risk?

    <p>Referring patients for add-on treatment</p> Signup and view all the answers

    Which of the following is a non-pharmacological strategy in the stepwise approach to control asthma symptoms and reduce risk?

    <p>Asthma education</p> Signup and view all the answers

    What is the primary goal of achieving a partnership between patient and healthcare providers in asthma management?

    <p>To minimize future risk of exacerbations and medication side-effects</p> Signup and view all the answers

    What is the definition of health literacy according to Rosas-Salazar (JACI 2012)?

    <p>The degree to which individuals have the capacity to obtain, process and understand basic health information and services to make appropriate health decisions</p> Signup and view all the answers

    Which of the following strategies is NOT recommended to reduce the impact of impaired health literacy?

    <p>Use medical language</p> Signup and view all the answers

    What is the primary goal of the control-based asthma management cycle?

    <p>To assess and adjust treatment</p> Signup and view all the answers

    What is the role of the 'teach-back' method in asthma management?

    <p>To ask patients to repeat instructions</p> Signup and view all the answers

    What is a key component of guided self-management education in asthma?

    <p>All of the above</p> Signup and view all the answers

    What is the primary goal of treating to control symptoms and minimize risk in asthma management?

    <p>To minimize future risk of exacerbations and medication side-effects</p> Signup and view all the answers

    What is the role of the healthcare system in asthma management?

    <p>To consider cultural and personal preferences</p> Signup and view all the answers

    What is the primary goal of assessing patient health literacy in asthma management?

    <p>To reduce the impact of impaired health literacy</p> Signup and view all the answers

    What is the primary goal of the 'Rules of Two' in asthma management?

    <p>To determine the appropriateness of asthma treatment</p> Signup and view all the answers

    What is the primary consideration before stepping up treatment for uncontrolled symptoms in asthma patients?

    <p>Verifying diagnosis, inhaler technique, and adherence</p> Signup and view all the answers

    In which group of patients may SLIT therapy be considered?

    <p>Adult HDM-sensitive patients with allergic rhinitis and exacerbations despite ICS treatment</p> Signup and view all the answers

    What is the minimum FEV1 requirement for considering SLIT therapy in adult HDM-sensitive patients with allergic rhinitis?

    <p>70% predicted</p> Signup and view all the answers

    What is the recommended duration of symptom control before considering stepping down treatment?

    <p>3 months</p> Signup and view all the answers

    Which of the following is a contraindication for ceasing ICS treatment?

    <p>Any of the above</p> Signup and view all the answers

    What is the primary goal of advising about non-pharmacological therapies and strategies?

    <p>To manage comorbidities and modifiable risk factors</p> Signup and view all the answers

    What are the two domains of asthma control?

    <p>Assess symptom control over the last 4 weeks and assess risk factors for poor outcomes</p> Signup and view all the answers

    What is the primary purpose of assessing inhaler technique and adherence?

    <p>To improve treatment effectiveness</p> Signup and view all the answers

    What is the significance of asking about side-effects in asthma management?

    <p>To improve treatment adherence</p> Signup and view all the answers

    Which of the following comorbidities may contribute to symptoms and poor quality of life in asthma patients?

    <p>Rhinosinusitis, GERD, obesity, obstructive sleep apnea, depression, and anxiety</p> Signup and view all the answers

    What is the purpose of the GINA assessment of symptom control?

    <p>To assess symptom control over the last 4 weeks</p> Signup and view all the answers

    What is the significance of asking about activity limitation due to asthma in the GINA assessment of symptom control?

    <p>To assess symptom control over the last 4 weeks</p> Signup and view all the answers

    What is the primary goal of assessing patient attitudes and goals for their asthma?

    <p>To develop a personalized treatment plan</p> Signup and view all the answers

    What is the significance of having a written asthma action plan?

    <p>To provide personalized guidance for asthma management</p> Signup and view all the answers

    What type of inflammation is often associated with allergic asthma?

    <p>Type 2 inflammation</p> Signup and view all the answers

    Which of the following is a characteristic of asthma with fixed airway obstruction?

    <p>Lack of inflammation</p> Signup and view all the answers

    What is a key feature of ASA-sensitive asthma?

    <p>Leukotriene-mediated inflammation</p> Signup and view all the answers

    Which of the following is NOT a differential diagnosis for asthma?

    <p>Hypertension</p> Signup and view all the answers

    What is a necessary component of the diagnosis of asthma?

    <p>A history of characteristic symptom patterns</p> Signup and view all the answers

    Which of the following is a characteristic of non-allergic asthma?

    <p>Neutrophilic inflammation</p> Signup and view all the answers

    What is a key feature of asthma with obesity?

    <p>Non-eosinophilic inflammation</p> Signup and view all the answers

    Which of the following is a goal of the diagnosis of asthma?

    <p>To document evidence for the diagnosis</p> Signup and view all the answers

    What is the recommended add-on therapy for patients with moderate asthma who are not controlled on low dose ICS?

    <p>Leukotriene receptor antagonists (LTRA)</p> Signup and view all the answers

    In which step of the stepwise approach to control asthma symptoms and reduce risk is it recommended to consider adding tiotropium?

    <p>STEP 3</p> Signup and view all the answers

    What is the recommended therapy for patients with severe asthma who are not controlled on high dose ICS and LABA?

    <p>Add-on anti-IgE</p> Signup and view all the answers

    Which of the following medications is recommended as a reliever therapy in asthma patients?

    <p>Short-acting beta2-agonist (SABA)</p> Signup and view all the answers

    What is the primary goal of providing guided self-management education to asthma patients?

    <p>To enhance self-monitoring and written action plan</p> Signup and view all the answers

    In which step of the stepwise approach to control asthma symptoms and reduce risk is it recommended to consider adding low dose ICS/formoterol?

    <p>STEP 2</p> Signup and view all the answers

    What is the recommended therapy for patients with mild asthma who are not controlled on as-needed SABA?

    <p>Low dose ICS/formoterol</p> Signup and view all the answers

    What should be considered in adult patients with allergic rhinitis who have exacerbations despite ICS treatment and a FEV1 of 70% predicted?

    <p>SLIT as an add-on therapy</p> Signup and view all the answers

    What is the primary goal of assessing modifiable risk factors and comorbidities in asthma patients?

    <p>To treat modifiable risk factors and comorbidities</p> Signup and view all the answers

    Why should patients with adult-onset asthma be asked about their work history?

    <p>To identify sensitizers and remove them as soon as possible</p> Signup and view all the answers

    What is the benefit of remediation of dampness or mold in homes?

    <p>It reduces asthma symptoms and medication use in adults</p> Signup and view all the answers

    What should be avoided in patients with asthma?

    <p>Medications that may worsen asthma</p> Signup and view all the answers

    What is a consideration for referral in patients with asthma?

    <p>Frequent asthma-related health care visits</p> Signup and view all the answers

    What should be considered in patients with asthma and a history of near-fatal exacerbation?

    <p>Risk factors for asthma-related death</p> Signup and view all the answers

    What is an essential component of guided asthma self-management and skills training?

    <p>All of the above, including skills training to use inhaler devices correctly</p> Signup and view all the answers

    What should be done before prescribing an inhaler device?

    <p>Choose an appropriate device for the patient</p> Signup and view all the answers

    Why is it important to address patients' fears and misconceptions about medications?

    <p>To increase medication adherence</p> Signup and view all the answers

    What should clinicians consider when patients think asthma is not serious?

    <p>They are less likely to follow the treatment plan</p> Signup and view all the answers

    What is the primary consideration for a patient to be on an ICS as a controller?

    <p>Symptoms more than twice a day</p> Signup and view all the answers

    What is the basis for selecting the preferred treatment at each step in population-level decisions?

    <p>Efficacy, effectiveness, safety, and availability</p> Signup and view all the answers

    What is the primary consideration when making individual patient decisions about controller options?

    <p>Patient preference and characteristics</p> Signup and view all the answers

    What is the purpose of discussing patient characteristics with the patient/parent/carer in individual patient decisions?

    <p>To identify known predictors of risk or response</p> Signup and view all the answers

    What is the primary goal of involving the patient/parent/carer in shared decision-making?

    <p>To discuss the patient's goals and concerns</p> Signup and view all the answers

    What is the purpose of considering patient preference in individual patient decisions?

    <p>To discuss the patient's goals and concerns</p> Signup and view all the answers

    What is the primary consideration when choosing between controller options at a population level?

    <p>Efficacy, effectiveness, safety, and availability</p> Signup and view all the answers

    What is the purpose of discussing preferred treatment options with the patient/parent/carer in individual patient decisions?

    <p>To discuss the preferred treatment for symptom control and risk reduction</p> Signup and view all the answers

    What is the primary challenge in treating COPD patients with multi-morbidity?

    <p>Managing complex symptoms and signs from multiple diseases</p> Signup and view all the answers

    What is the implication of most evidence coming from trials in patients with COPD as the only significant disease?

    <p>Treatments may not be effective for patients with multi-morbidity</p> Signup and view all the answers

    What is the primary reason for keeping treatments simple in patients with multi-morbidity?

    <p>To minimize the burden of polypharmacy</p> Signup and view all the answers

    What is the characteristic of multi-morbid patients?

    <p>They have multiple chronic conditions</p> Signup and view all the answers

    What is the implication of the presence of COPD in the majority of multi-morbid patients?

    <p>COPD is a common comorbidity in multi-morbid patients</p> Signup and view all the answers

    What is the primary goal of treating COPD patients with multi-morbidity?

    <p>To manage complex symptoms and signs from multiple diseases</p> Signup and view all the answers

    What is the primary focus of the initial assessment of a patient with a cough?

    <p>Conducting a thorough history</p> Signup and view all the answers

    Which of the following is a common complaint in geriatric patients with pulmonary disease?

    <p>Dyspnea</p> Signup and view all the answers

    What is a potential differential diagnosis for a patient with a cough?

    <p>All of the above</p> Signup and view all the answers

    What is a characteristic of a patient's cough that may indicate asthma?

    <p>Nonproductive cough</p> Signup and view all the answers

    What is a potential underlying cause of a cough in a geriatric patient?

    <p>All of the above</p> Signup and view all the answers

    What is an important aspect of the initial assessment of a patient with dyspnea?

    <p>Conducting a thorough history</p> Signup and view all the answers

    What is a characteristic of asthma?

    <p>A chronic disease that can be controlled but not cured</p> Signup and view all the answers

    What is the main cause of symptoms in asthma?

    <p>Variable expiratory airflow limitation</p> Signup and view all the answers

    What is a factor that can trigger or worsen asthma symptoms?

    <p>Exercise</p> Signup and view all the answers

    What is a benefit of well-controlled asthma?

    <p>Patients have fewer symptoms during the day and night</p> Signup and view all the answers

    What is the definition of asthma?

    <p>A heterogeneous disease characterized by chronic airway inflammation</p> Signup and view all the answers

    What is a characteristic of asthma symptoms?

    <p>They vary over time in their occurrence, frequency, and intensity</p> Signup and view all the answers

    What is associated with variable expiratory airflow limitation in asthma?

    <p>Bronchoconstriction, airway wall thickening, and increased mucus</p> Signup and view all the answers

    What is the goal of treating asthma?

    <p>To control asthma symptoms and minimize risk</p> Signup and view all the answers

    What is the primary focus of advising about non-pharmacological therapies and strategies in asthma management?

    <p>To treat modifiable risk factors and comorbidities</p> Signup and view all the answers

    Which of the following is a consideration before stepping up treatment for uncontrolled symptoms in asthma patients?

    <p>Checking diagnosis and inhaler technique</p> Signup and view all the answers

    What is the recommended duration of symptom control before considering stepping down treatment in asthma patients?

    <p>3 months</p> Signup and view all the answers

    What is the primary goal of guided self-management education in asthma?

    <p>To provide education on inhaler technique and adherence</p> Signup and view all the answers

    Which of the following comorbidities may contribute to symptoms and poor quality of life in asthma patients?

    <p>Smoking, obesity, and anxiety</p> Signup and view all the answers

    What is the primary role of SLIT therapy in asthma management?

    <p>To provide adjunctive therapy for patients with allergic rhinitis and uncontrolled symptoms</p> Signup and view all the answers

    What is the primary consideration before adding SLIT therapy in adult HDM-sensitive patients with allergic rhinitis?

    <p>The patient's FEV1 level</p> Signup and view all the answers

    What is the primary goal of treating modifiable risk factors and comorbidities in asthma management?

    <p>To improve overall health and quality of life</p> Signup and view all the answers

    What is the primary cause of mortality in older adults with CAP?

    <p>Sepsis</p> Signup and view all the answers

    Which of the following is a characteristic of Mycoplasma pneumoniae?

    <p>No cell wall</p> Signup and view all the answers

    What is the recommended duration of antibiotic therapy for CAP?

    <p>Minimum of 5 days, with extension based on clinical response</p> Signup and view all the answers

    Which of the following is a common cause of chronic cough in smokers?

    <p>Chronic bronchitis</p> Signup and view all the answers

    What is the definition of bronchiectasis?

    <p>Dilation of the airways with chronic infection</p> Signup and view all the answers

    What is the primary goal of the CURB-65 mortality prediction tool?

    <p>To predict mortality risk in patients with CAP</p> Signup and view all the answers

    Which of the following is a characteristic of obstructive sleep apnea (OSA)?

    <p>Pause in breathing for 10-90 seconds</p> Signup and view all the answers

    What is the primary goal of the Fleischner Society guidelines for the management of incidental pulmonary nodules?

    <p>To guide the management of incidental pulmonary nodules</p> Signup and view all the answers

    What is the definition of a single pulmonary nodule?

    <p>A solitary lesion in the lung parenchyma</p> Signup and view all the answers

    Which of the following is a consideration in the diagnosis of rhinosinusitis in older adults?

    <p>The presence of multiple comorbidities</p> Signup and view all the answers

    Study Notes

    Aging and COPD

    • With age, there is a decline in forced vital capacity, FEV1, and PaO2, while the A-a gradient increases.
    • Clinically significant dyspnea is often under-reported and unrecognized in older adults.
    • 5%–10% of people ≥65 years meet criteria for asthma.
    • COPD is the third leading cause of death in older adults.
    • Pharmacologic treatment for COPD chiefly consists of inhaled bronchodilators and steroids.
    • Smoking cessation will slow the decline in lung function at any age.

    Burden of Asthma

    • Asthma is one of the most common chronic diseases worldwide with an estimated 300 million affected individuals.
    • Prevalence is increasing in many countries, especially in children.
    • Asthma is a major cause of school and work absence.
    • Health care expenditure on asthma is very high, with developed economies expecting to spend 1-2% of total health care expenditures on asthma.

    Stepwise Approach to Control Asthma Symptoms and Reduce Risk

    • Diagnosis involves symptom control, risk factors, inhaler technique, adherence, and patient preference.
    • Assess symptoms, exacerbations, side effects, patient satisfaction, and lung function.
    • Asthma medications and non-pharmacological strategies are used to treat modifiable risk factors.
    • Refer for add-on treatment if necessary.

    Assessing Asthma Severity

    • Asthma severity is assessed retrospectively from the level of treatment required to control symptoms and exacerbations.
    • Risk reduction is necessary to minimize future risk of exacerbations, fixed airflow limitation, and medication side-effects.
    • A partnership between patient and healthcare provider is essential for achieving this goal.

    Reducing the Impact of Impaired Health Literacy

    • Health literacy affects health outcomes, including in asthma.
    • Strategies for reducing the impact of impaired health literacy include:
      • Prioritizing information
      • Speaking slowly and avoiding medical language
      • Simplifying numeric concepts
      • Using anecdotes, drawings, pictures, tables, and graphs
      • Using the 'teach-back' method
      • Asking a second person to repeat main messages
      • Paying attention to non-verbal communication

    Treating to Control Symptoms and Minimize Risk

    • Establish a patient-provider partnership
    • Manage asthma in a continuous cycle: assess, adjust treatment, and review response
    • Teach and reinforce essential skills, including inhaler skills, adherence, and guided self-management education
    • Use a written asthma action plan and self-monitoring with regular medical review

    Asthma Treatment

    • Low-dose ICS/LABA or tiotropium, anti-IgE, or anti-IL5 are treatment options
    • Low-dose ICS can be used as a controller, or add tiotropium or low-dose theophylline
    • Leukotriene receptor antagonists (LTRA) can be used as an alternative
    • High-dose ICS or OCS can be used for severe cases

    Asthma Phenotypes

    • Allergic (extrinsic) asthma: IgE mediated or mast cell mediated, may respond to specific targeted therapies
    • Non-allergic (intrinsic) asthma: eosinophilic or neutrophilic, may be ICS responsive or resistant
    • Asthma with fixed airway obstruction: lack of inflammation, defective repair mechanisms, and airway smooth muscle abnormalities
    • Asthma with obesity: non-eosinophilic, obesity required

    Differential Diagnoses

    • Foreign body, viral infections, pulmonary infections, MVP, PE, CHF, COPD, drugs (ACE inhibitors, Beta blockers, NSAIDS, ASA)

    Diagnosis of Asthma

    • Based on history of characteristic symptom patterns and evidence of variable airflow limitation
    • Document evidence for diagnosis in patient's notes before starting controller treatment
    • Asthma is characterized by airway inflammation and airway hyperresponsiveness

    Asthma Control

    • Assess symptom control over the last 4 weeks
    • Assess risk factors for poor outcomes, including low lung function
    • Asthma control has two domains: symptom control and risk factors

    Treatment Issues

    • Check inhaler technique and adherence
    • Ask about side-effects
    • Does the patient have a written asthma action plan?
    • What are the patient's attitudes and goals for their asthma?

    GINA Assessment of Symptom Control

    • Assess daytime asthma symptoms, night waking, reliever use, and activity limitation
    • GINA assessment has three levels: well-controlled, partly controlled, and uncontrolled

    Choosing Between Controller Options

    • Population-level decisions: based on efficacy, effectiveness, safety, availability, and cost
    • Individual patient decisions: based on shared decision-making, patient characteristics, patient preference, and advice about exercise-induced bronchoconstriction

    Important Considerations

    • Occupational asthma: ask about work history, remove sensitizers, and refer for expert advice
    • Avoid medications that may worsen asthma (NSAIDs, beta-blockers)
    • Remediation of dampness or mold in homes reduces asthma symptoms and medication use
    • Sublingual immunotherapy (SLIT) can be used as add-on therapy

    Indications for Referral

    • Difficulty confirming the diagnosis of asthma
    • Symptoms suggesting chronic infection, cardiac disease, etc.
    • Suspected occupational asthma
    • Persistent uncontrolled asthma or frequent exacerbations
    • Risk factors for asthma-related death
    • Significant side-effects (or risk of side-effects)
    • Symptoms suggesting complications or sub-types of asthma

    Pulmonary Disease Management

    • Pulmonary disease management involves understanding common complaints, geriatric specific considerations, and the major players in the disease.

    Common Complaints

    • Cough is a common complaint, with differential diagnoses including prescription drugs, cerumen impaction, post nasal drip, COPD, asthma, postinfection, GERD, and occupational or environmental factors.
    • Dyspnea is a common complaint, with underlying causes to be identified.
    • Hemoptysis is a common complaint, with underlying causes to be identified.

    Cough

    • A thorough history is necessary to diagnose the cause of a cough, including:
      • When did it begin?
      • When does it occur?
      • What stimulates it/aggravates it?
      • What makes it better?
      • Describe the quality (productive or nonproductive?)
    • Cough can be a symptom of various conditions, including URIs, acute and chronic bronchitis, pneumonia, single pulmonary nodule, and obstructive sleep apnea.

    The Major Players

    • Asthma is a major player in pulmonary disease management.
    • COPD is a major player in pulmonary disease management.### Pneumococcal Pneumonia
    • Caused by Streptococcus pneumoniae (gram-positive)
    • Abrupt onset
    • Common symptoms:
      • Productive cough with rusty-colored sputum
      • Fever
      • Chills
      • Pleuritic chest pain
      • More subtle presentation in older patients (e.g., altered mental status, weakness)

    Atypical Pneumonia

    • Caused by Mycoplasma pneumoniae (no cell wall)
    • Common symptoms:
      • Headache
      • Sore throat
      • Myalgia
      • Dry hacking cough
      • May be clinically indistinguishable from pneumococcal pneumonia

    Differences in Presentation

    • Mycoplasma pneumonia:
      • Sore throat, fever, dry hacking cough
      • Complications: sinusitis, otitis media, erythema multiforme, or erythema nodosum
      • Persistent hacking cough for up to 6 weeks
      • Relapse occurs in 10% of cases
    • Chlamydia pneumonia:
      • Biphasic illness
      • Younger individuals affected
      • Severe pharyngitis and laryngitis
      • Fever
      • Cough

    Physical Exam

    • No specific signs can confirm pneumonia
    • Physical exam cannot reliably distinguish type of pneumonia
    • Tachypnea more common in older adults
    • Pulse oximetry screening should be performed if suspecting CAP
    • Other signs: fever, increased tactile fremitus, dullness to percussion, egophony, crackles (rales), bronchial breath sounds

    Diagnostic Testing

    • CXR required to differentiate
    • Normal CXR does not exclude diagnosis
    • Additional tests:
      • Pulse oximetry
      • CBC with differential
      • Electrolytes
      • Rapid test for influenza (if suspected)
      • Sputum culture and gram stain (for severely ill, immunosuppressed, or HIV+ patients)
      • Blood cultures (for severely ill, immunosuppressed, or HIV+ patients)
      • Urinary antigen testing for Legionella and pneumococcus (for severely ill, immunosuppressed, or HIV+ patients)
      • CRP and procalcitonin level (if suspected inadequate response to treatment)

    CAP Treatment

    • Hydration
    • Respiratory hygiene
    • ASA or acetaminophen for fever and headache
    • Smoking cessation
    • Prevention: pneumococcal and influenza vaccine
    • Empiric treatment:
      • Outpatient: azithromycin, clarithromycin, or doxycycline
      • Inpatient (non-ICU): levofloxacin, moxifloxacin, or combination of beta-lactam and azithromycin
      • Inpatient (ICU): combination of beta-lactam and azithromycin or levofloxacin or moxifloxacin
      • Duration of therapy: minimum 5 days, should be afebrile for 48-72 hours

    CURB-65 Mortality Prediction Tool

    • Urea (BUN ≥ 20 mg/dL)
    • Respiratory rate (≥ 30/min)
    • Blood pressure (systolic ≤ 90 mmHg or diastolic ≤ 60 mmHg)
    • Confusion (altered mental status)
    • Age (≥ 65 years)

    Follow-up

    • Telephone follow-up in 24 hours
    • Office visit in 3-4 days
    • Repeat CXR in 2-4 weeks
    • Clinical failures: poor compliance with medications, resistant organisms, unusual pathogens, non-infectious causes

    Chronic Cough

    • Subacute cough: 3-8 weeks
    • Chronic cough: > 8 weeks
    • Common causes:
      • Postnasal drip
      • GERD
      • Asthma
      • Cigarette smoking
      • Postnasal drip, allergies, chronic sinusitis
    • Evaluation:
      • History: development, duration, character, precipitants
      • Physical exam: ENT, lungs, cardiac, abdomen
      • CXR: excludes malignant disease, bronchiectasis, persistent pneumonia, sarcoidosis, TB
      • Spirometry

    Bronchiectasis

    • Chronic cough
    • Overproduction of secretions
    • Reduced clearance of secretions
    • Result: excess airway secretions

    Sleep Apnea

    • Pause in breathing for 10-90 seconds
    • Central apneas: absent airflow and respiratory efforts
    • Obstructive apneas: tongue and soft palate fall backward
    • Mixed apneas
    • Consequences: pulmonary hypertension, hypertension with LV dysfunction, cardiac dysrhythmias, psychomotor defects, hypoxia and hypercapnia

    Geriatric Specific Considerations

    • Age-related pulmonary changes:

      • Reduced airway size
      • Shallow alveolar sacs
      • Decline in chest wall compliance
      • Intercostal muscle atrophy
      • Reduction in diaphragmatic strength
    • Difficulties in recognizing respiratory symptoms

    • Rhinosinusitis: approaches to diagnosis, treatment do not differ with age

    • Dyspnea: common causes include COPD, cardiac disease, asthma, interstitial lung disease, deconditioning### COPD and Comorbidities

    • COPD is often present in patients with multi-morbidity, defined as having two or more chronic conditions.

    • Multi-morbid patients have complex symptoms and signs that can be attributed to several causes during chronic and acute events.

    • There is no evidence to suggest that COPD should be treated differently in patients with multi-morbidity.

    • Treatments for multi-morbid patients should be kept simple to avoid polypharmacy.

    Non-Pharmacological Therapies and Strategies

    • Advise patients on non-pharmacological therapies and strategies, such as physical activity, weight loss, and avoidance of sensitizers.
    • Consider stepping up treatment if patients experience uncontrolled symptoms, exacerbations, or risks.
    • Check diagnosis, inhaler technique, and adherence before stepping up treatment.
    • Consider adding SLIT (Sublingual Immunotherapy) in adult HDM-sensitive patients with allergic rhinitis who have exacerbations despite ICS treatment, if FEV1 is >70% predicted.

    Asthma Definition and Facts

    • Asthma is a common and potentially serious chronic disease that can be controlled but not cured.
    • Symptoms of asthma include wheezing, shortness of breath, chest tightness, and cough, which vary over time in their occurrence, frequency, and intensity.
    • Symptoms are associated with variable expiratory airflow limitation due to bronchoconstriction, airway wall thickening, and increased mucus.
    • Factors that can trigger or worsen symptoms include viral infections, allergens, tobacco smoke, exercise, and stress.

    Effective Treatment of Asthma

    • Asthma can be effectively treated to:
      • Avoid troublesome symptoms during the day and night
      • Need little or no reliever medication
      • Have productive, physically active lives
      • Have normal or near-normal lung function
      • Avoid serious asthma flare-ups (exacerbations or severe attacks)

    Key Reminders

    • Provide guided self-management education to patients
    • Treat modifiable risk factors and comorbidities
    • Consider stepping up or down treatment based on symptoms and risk of exacerbations
    • Ceasing ICS is not advised

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    Description

    This quiz covers the changes in lung function with age, the prevalence of asthma and COPD in older adults, and the importance of recognizing dyspnea.

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