Chronic Liver Injury Pathology
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Questions and Answers

What is the final common pathway of many types of chronic liver injury?

  • Extensive fibrosis (correct)
  • Hepatocyte necrosis
  • Distortion of vascular bed
  • Connective tissue deposition

    • Which mechanism contributes to the development of portal hypertension in liver cirrhosis?

  • Increased resistance to portal flow (correct)
  • Decreased portal flow
  • Decreased splanchnic flow
  • Active hepatic vasodilation

    • In chronic liver disease, which factor is associated with the development of ascites?

  • Serum bilirubin >3 mg/dL
  • Hepatic venous pressure gradient (HVPG) >12 mm Hg (correct)
  • Development of esophageal varices
  • Serum albumin >3.5 g/dL

    • What are the common causes of liver cirrhosis?

    <p>Viral hepatitis</p> Signup and view all the answers

    What is the median survival for individuals with decompensated cirrhosis?

    <p>1.6 years</p> Signup and view all the answers

    What develops in 50-60% of cirrhotic patients?

    <p>Esophageal varices</p> Signup and view all the answers

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