5 Questions
What initiates the process of tissue repair in chronic inflammation?
Macrophages
Which cells are involved in chronic inflammation?
Macrophages, lymphocytes, and plasma cells
Which type of exposure can lead to chronic inflammation of the lung?
Prolonged exposure to undegraded toxic material like silicosis or asbestosis
What is the role of macrophages in chronic inflammation?
Ingest and eliminate microbes, initiate tissue repair, secrete mediators of inflammation
What may cause chronic inflammation following acute inflammation?
(chronic lung abscess may follow pneumonia with the persistence of causative agent)
Study Notes
Chronic Inflammation
- Damaged tissue and exposure to toxic substances or pathogens initiate the process of tissue repair in chronic inflammation.
Cells Involved in Chronic Inflammation
- Macrophages, lymphocytes, and plasma cells are key cells involved in chronic inflammation.
Causes of Chronic Inflammation
- Prolonged exposure to pollutants, irritants, or allergens, such as silica or asbestos, can lead to chronic inflammation of the lung.
Role of Macrophages
- Macrophages play a crucial role in chronic inflammation by engulfing foreign substances and producing chemical signals that attract other immune cells to the site of inflammation.
Progression from Acute to Chronic Inflammation
- Inadequate resolution of acute inflammation, persistent infection, or autoimmune disorders may cause chronic inflammation following acute inflammation.
Test your knowledge about chronic inflammation, including the characteristics, cell infiltration, tissue destruction, and repair processes involved in long-term inflammatory conditions.
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