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Questions and Answers
What type of granulomatous inflammation is associated with sarcoidosis?
What type of granulomatous inflammation is associated with sarcoidosis?
Which of the following is NOT a type of infectious granuloma?
Which of the following is NOT a type of infectious granuloma?
What type of cells are predominantly found in chronic inflammation?
What type of cells are predominantly found in chronic inflammation?
Which type of granuloma is primarily formed by fused macrophages?
Which type of granuloma is primarily formed by fused macrophages?
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Which classification of granulomatous inflammation includes silicosis?
Which classification of granulomatous inflammation includes silicosis?
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In acute inflammation, which cell type is primarily responsible for pus formation?
In acute inflammation, which cell type is primarily responsible for pus formation?
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Which of the following is true regarding the cells found in chronic inflammation?
Which of the following is true regarding the cells found in chronic inflammation?
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Which pair correctly associates a granulomatous condition with its etiology?
Which pair correctly associates a granulomatous condition with its etiology?
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What is a primary characteristic of chronic inflammation?
What is a primary characteristic of chronic inflammation?
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Which of the following conditions can lead to chronic inflammation?
Which of the following conditions can lead to chronic inflammation?
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What type of cells mainly infiltrate the tissues during chronic inflammation?
What type of cells mainly infiltrate the tissues during chronic inflammation?
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What may occur as a result of chronic inflammatory reactions?
What may occur as a result of chronic inflammatory reactions?
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Which of these statements about the causes of chronic inflammation is true?
Which of these statements about the causes of chronic inflammation is true?
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Which of the following is NOT a morphologic feature of chronic inflammation?
Which of the following is NOT a morphologic feature of chronic inflammation?
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What is a key mediator in the process of chronic inflammation?
What is a key mediator in the process of chronic inflammation?
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Chronic inflammation may develop from a failure of the immune system after what type of inflammation?
Chronic inflammation may develop from a failure of the immune system after what type of inflammation?
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Which type of agent can cause chronic inflammation through constant exposure?
Which type of agent can cause chronic inflammation through constant exposure?
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Which characteristic is NOT typical of chronic inflammation?
Which characteristic is NOT typical of chronic inflammation?
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What typically follows acute inflammation and is characterized by the same microscopic features, regardless of the irritant?
What typically follows acute inflammation and is characterized by the same microscopic features, regardless of the irritant?
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Which of the following features is characteristic of granulomatous inflammation?
Which of the following features is characteristic of granulomatous inflammation?
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What type of cells are primarily found in a granuloma?
What type of cells are primarily found in a granuloma?
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Which of the following is NOT typically associated with granulomas?
Which of the following is NOT typically associated with granulomas?
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How is chronic specific inflammation primarily distinguished from chronic non-specific inflammation?
How is chronic specific inflammation primarily distinguished from chronic non-specific inflammation?
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What is one of the attempts by tissues to repair themselves during chronic inflammation?
What is one of the attempts by tissues to repair themselves during chronic inflammation?
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Which of the following statements about tissue exudate in chronic inflammation is accurate?
Which of the following statements about tissue exudate in chronic inflammation is accurate?
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In granulomas, which cells are typically aggregated in a circumscribed collection?
In granulomas, which cells are typically aggregated in a circumscribed collection?
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Which of the following is a typical feature of chronic inflammation?
Which of the following is a typical feature of chronic inflammation?
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Study Notes
Chronic Inflammation
- Definition:
- Inflammation of prolonged duration ("weeks to years")
- In which inflammation, tissue destruction & healing occurs in same time in varying combinations.
- The chronic inflammatory reactions may promote tumor development.
Causes of Chronic Inflammation
- May follow acute inflammation due to failure of immunity.
- May start chronic by gradual onset due to:
- Infection with resistant organisms that are difficult to eradicate, such as T.B.
- Prolonged exposure to potentially toxic agents, e.g. Silicosis, atherosclerosis
- Development of hypersensitivity diseases/autoimmunity
Morphologic Features
- Infiltration with mononuclear cells: Chronic inflammation is mediated by cytokines → amplify and prolong the inflammatory reaction.
- Tissue destruction: induced by the persistent offending agent or by the inflammatory cells.
- Attempts at healing: replacement of damaged tissue, by proliferation of small blood vessels (and fibrosis).
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Description
This quiz explores the definition, causes, and morphological features of chronic inflammation. Understanding chronic inflammation is crucial for recognizing its role in various diseases, including tumor development. Dive into the mechanisms behind prolonged inflammatory responses and their implications.
