Chronic and Acute Idiopathic Thrombocytopenic Purpura (ITP)
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Questions and Answers

Which of the following disorders is characterized by blood vessels that become more fragile?

  • Lupus
  • Scleroderma
  • Rheumatoid arthritis
  • Senile purpura (correct)

    • What is the main characteristic of abnormal bleeding associated with thrombocytopenia or abnormal platelet function?

  • Petechiae (correct)
  • Easy bruising
  • Cavernous hemangioma
  • Prolonged bleeding after trauma

    • What is the most common site for giant cavernous hemangiomas?

  • Brain
  • Lungs
  • Kidneys
  • Liver (correct)

    • What causes senile purpura?

    <p>Fragility of blood vessels</p> Signup and view all the answers

    Which of the following is a characteristic feature of scurvy?

    <p>Severe lack of vitamin C in the diet</p> Signup and view all the answers

    What is the main difference between arterial, venous, and capillary bleeding?

    <p>Pressure at which the blood is coming out</p> Signup and view all the answers

    What platelet count is considered low in the diagnosis of thrombocytopenia?

    <p>Below 50,000/microliter</p> Signup and view all the answers

    Which of the following is NOT a common clinical feature of thrombocytopenia?

    <p>Iron deficiency anemia</p> Signup and view all the answers

    Which treatment option is specifically mentioned in the text for Chronic idiopathic thrombocytopenic purpura?

    <p>Corticosteroids</p> Signup and view all the answers

    What is the most common cause of thrombocytopenia without anemia or neutropenia?

    <p>Autoimmune thrombocytopenic purpura</p> Signup and view all the answers

    What is the main difference between acute and chronic idiopathic thrombocytopenic purpura in terms of duration?

    <p>Acute resolves in less than 6 months, chronic lasts longer than 6 months</p> Signup and view all the answers

    Which of the following is a method to increase platelet count mentioned in the text?

    <p>High-dose intravenous immunoglobulin therapy</p> Signup and view all the answers

    What is post-transfusion purpura (PTP) characterized by?

    <p>Severe thrombocytopenia occurring after a blood transfusion</p> Signup and view all the answers

    Which drugs increase platelet production by activating the thrombopoietin receptor on megakaryocytes?

    <p>Romiplostim and eltrombopag</p> Signup and view all the answers

    What is the purpose of platelet transfusion in the context of thrombocytopenia?

    <p>To increase platelet count in case of bleeding or before invasive procedures</p> Signup and view all the answers

    What is eltrombopag used for in the treatment of thrombocytopenia?

    <p>To increase platelet count in adults with ITP</p> Signup and view all the answers

    What is the main cause of thrombocytopenia post-blood transfusion according to the text?

    <p>Development of antibodies against HPA-1a on the transfused platelets</p> Signup and view all the answers

    Which drugs are considered thrombomimetics according to the text?

    <p>Romiplostim and eltrombopag</p> Signup and view all the answers

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