Chromosomes and Heredity Quiz

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Questions and Answers

What is the function of chromosomes in heredity?

  • They act as structural components of the cell.
  • They produce energy for cellular activities.
  • They link generations through the transmission of genetic material. (correct)
  • They store nutrients needed for cell growth.

Which type of chromosome has its centromere located at the center?

  • Acrocentric
  • Metacentric (correct)
  • Telocentric
  • Submetacentric

Which chromosome type has unequal arm lengths due to the position of its centromere?

  • Submetacentric (correct)
  • Metacentric
  • Telocentric
  • Acrocentric

What shape do metacentric chromosomes assume during anaphase?

<p>V-shaped (B)</p> Signup and view all the answers

What type of chromosomes do humans lack?

<p>Telocentric (D)</p> Signup and view all the answers

Which chromosome types are classified as acrocentric in humans?

<p>13, 15, 21, and 22 (C)</p> Signup and view all the answers

During what process are chromosomes instrumental in directing protein synthesis?

<p>Transcription (D)</p> Signup and view all the answers

What does the genetic material within chromosomes primarily consist of?

<p>DNA or RNA (A)</p> Signup and view all the answers

What does a karyotype represent?

<p>The phenotypic appearance of chromosomes in a species (B)</p> Signup and view all the answers

Which of the following is a characteristic of an asymmetric karyotype?

<p>A large variation between chromosome sizes (B)</p> Signup and view all the answers

What is an idiogram?

<p>A diagrammatic representation of karyotype (A)</p> Signup and view all the answers

Which statement is true regarding symmetric karyotype?

<p>It consists of numerous metacentric chromosomes. (C)</p> Signup and view all the answers

What aspect of chromosomes is considered in the study of karyotype?

<p>Chromosome number, size, and position of centromeres (A)</p> Signup and view all the answers

Which karyotype type is believed to represent a primitive state?

<p>Symmetric karyotype (A)</p> Signup and view all the answers

How are chromosomes organized in an idiogram?

<p>In descending order of size (A)</p> Signup and view all the answers

What determines the genetic identity of a karyotype?

<p>The structural features of chromosomes unique to a species (B)</p> Signup and view all the answers

What role do non-genetic RNAs play in cellular organisms?

<p>They perform different genetically controlled cellular functions. (D)</p> Signup and view all the answers

Which amino acids are predominantly found in histones?

<p>Lysine and Arginine (A)</p> Signup and view all the answers

In what ratio are the five types of histones generally present in eukaryotic chromosomes?

<p>1H1:2H2a:2H2b:2H3:2H4 (B)</p> Signup and view all the answers

What is the primary function of histones in relation to DNA?

<p>To bind tightly to each other and stabilize chromatin structure. (D)</p> Signup and view all the answers

How are non-histone proteins different from histones?

<p>They perform distinct metabolic functions. (B)</p> Signup and view all the answers

What is the composition of chromatin in eukaryotic cells?

<p>DNA complexed with histones and non-histones. (C)</p> Signup and view all the answers

What is a unique characteristic of the histones found in sperm cells of certain eukaryotes?

<p>They are replaced by protamines. (A)</p> Signup and view all the answers

Which type of protein is NOT present in lower proportions compared to histones?

<p>Histones (D)</p> Signup and view all the answers

What is the primary purpose of C-banding in chromosome analysis?

<p>To emphasize the centromeric region (A)</p> Signup and view all the answers

Which staining method produces a pattern that is the opposite of G-banding?

<p>R-banding (D)</p> Signup and view all the answers

How does the T-banding technique differ from C-banding?

<p>T-banding focuses on telomeres and not the centromeres. (C)</p> Signup and view all the answers

What does a normal human karyotype indicate?

<p>46 chromosomes with no abnormalities (D)</p> Signup and view all the answers

Which of the following characteristics is NOT typically observed when comparing karyotypes?

<p>Differences in RNA content (B)</p> Signup and view all the answers

Why are white blood cells commonly used for karyotyping?

<p>They are easily induced to divide and can grow in culture. (A)</p> Signup and view all the answers

What may lead to developmental abnormalities in humans?

<p>Changes in basic chromosome number (D)</p> Signup and view all the answers

Which factor can lead to differences in the relative size of chromosomes?

<p>Segmental interchange of unequal lengths (B)</p> Signup and view all the answers

What defines a bisexual flower?

<p>It has both androecium and gynoecium. (A)</p> Signup and view all the answers

Which of the following statements about unisexual flowers is true?

<p>They can be either male or female but not both. (D)</p> Signup and view all the answers

What is autogamy in the context of bisexual flowers?

<p>Pollination within the same flower. (B)</p> Signup and view all the answers

Which process involves pollination between different flowers on the same plant?

<p>Geitonogamy (B)</p> Signup and view all the answers

What is the primary role of heterochromatin in the cell?

<p>Maintains structural integrity of the genome (C)</p> Signup and view all the answers

What characteristic distinguishes bisexual flowers from unisexual flowers?

<p>Bisexual flowers contain both reproductive organs. (D)</p> Signup and view all the answers

Which type of pollination occurs before the flower opens?

<p>Cleistogamy (B)</p> Signup and view all the answers

Which type of chromatin is found towards the periphery of the nucleus?

<p>Constitutive heterochromatin (B)</p> Signup and view all the answers

Which flower type can produce genetically identical offspring through self-pollination?

<p>Bisexual flowers (C)</p> Signup and view all the answers

Which statement is true about euchromatin compared to heterochromatin?

<p>Euchromatin allows transcription and genetic variation to occur. (B)</p> Signup and view all the answers

What is true about monoecious plants?

<p>They possess both male and female flowers on the same plant. (C)</p> Signup and view all the answers

What is the main difference in the replication timing between euchromatin and heterochromatin?

<p>Heterochromatin replicates later than euchromatin. (B)</p> Signup and view all the answers

Which of the following best describes the forms of heterochromatin?

<p>Exists as facultative and constitutive forms (B)</p> Signup and view all the answers

During which phase of the cell cycle do the matrix and pellicle appear?

<p>Metaphase (B)</p> Signup and view all the answers

What characterizes the genetic processes that affect euchromatin?

<p>They allow for varied allelic expression within the nucleus. (B)</p> Signup and view all the answers

What type of chromatin does not exhibit heteropycnosis?

<p>Euchromatin (D)</p> Signup and view all the answers

Flashcards

Non-genetic RNA

RNA molecules in cellular organisms that don't carry genetic information. They perform various cellular functions under genetic control.

Histones

Basic proteins found in eukaryotic cells. They bind to DNA, helping to package it into chromatin.

Chromatin

The complex of DNA and proteins (histones and non-histones) that forms the building blocks of chromosomes.

Nucleosome

The basic structural unit of chromatin, consisting of DNA wrapped around a core of histone proteins.

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Types of Histones

There are five main types of histones: H1, H2A, H2B, H3, and H4. They differ in their amino acid composition and play various roles in chromatin structure.

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Non-histone proteins

Acidic proteins found in chromatin, responsible for a wide range of functions like DNA replication and repair.

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Protamines

A class of small basic proteins found in the sperm of some eukaryotes, replacing histones for a more compact DNA structure.

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Functions of non-histone proteins

Non-histone proteins participate in various metabolic activities within the nucleus, including DNA replication, transcription, and repair.

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What is a karyotype?

A karyotype is a representation of the complete set of chromosomes in a species. It considers factors like chromosome number, size, centromere position, and banding patterns.

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What is special about a karyotype for a particular species?

The karyotype is genetically identical within a species. However, it differs between species.

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How do karyotypes help us understand evolution?

Comparing karyotypes of different species reveals similarities and differences, shedding light on their evolutionary relationships.

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What is an asymmetric karyotype?

An asymmetric karyotype has a large difference between the smallest and largest chromosomes, and fewer metacentric chromosomes.

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What is a symmetric karyotype?

A symmetric karyotype has a smaller difference between the smallest and largest chromosomes, and more metacentric chromosomes.

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What is an idiogram?

An idiogram is a diagrammatic representation of a karyotype. It shows chromosomes arranged in decreasing size order.

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What is the significance of an idiogram?

Idiograms help us understand chromosome structure and evolution. The arrangement of chromosomes in an idiogram provides insights into evolutionary relationships.

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How are chromosomes arranged in an idiogram?

In an idiogram, chromosomes are arranged in descending order of size, with their centromeres aligned in a straight line.

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R-banding

A chromosome banding technique that produces a pattern opposite to G-banding, highlighting terminal bands that are light after G-banding. It involves treating chromosomes with heat and staining them with Giemsa.

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C-banding

A chromosome banding technique that emphasizes the centromeric region. It's achieved by treating chromosomes with alkali and controlling hydrolysis with buffer salt solutions.

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NOR staining

A chromosome banding technique that highlights the nucleolar organizer region (NOR), which is responsible for ribosome production.

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T-banding

A chromosome banding technique that stains the telomeres, the ends of chromosomes.

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Karyotype

The complete set of chromosomes in a cell or organism. It's a visual representation of the chromosomes arranged in order of size and shape.

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Translocation

A type of chromosomal rearrangement where a segment of one chromosome breaks off and attaches to another chromosome.

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Segmental Interchange

A chromosomal change where unequal lengths of chromosomes are exchanged, leading to differences in relative chromosome size.

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Dislocation Hypothesis

A hypothesis explaining how changes in chromosome number occur. It suggests that successive unequal translocations can ultimately lead to the loss of a chromosome with no negative impact on the organism.

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Homologous Chromosomes

Pairs of chromosomes with the same genes but possibly different alleles, one from each parent. They look alike and have the same length, centromere position, and gene locations.

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Partially Homologous Chromosomes

Sex chromosomes (X and Y) in some organisms, where the X chromosome is longer and has more genes than the Y chromosome. They have some genes in common but are not identical in size or gene content.

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Bisexual Flower

A complete flower with both male (stamens) and female (pistils) reproductive organs, allowing for self-pollination and cross-pollination.

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Unisexual Flower

An incomplete flower containing only male or female reproductive organs, requiring cross-pollination for fertilization.

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Monoecious Plant

A plant that produces separate male and female flowers on the same individual, allowing for self-pollination.

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Autogamy

Self-pollination that occurs within the same flower.

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Geitonogamy

Self-pollination that occurs between different flowers of the same plant.

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Cleistogamy

Self-pollination that occurs before the flower opens.

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What makes chromosomes the organs of heredity?

Chromosomes are considered the organs of heredity because they act as the link between generations, carry genetic material, and control the synthesis of proteins.

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What is a diploid chromosome set?

A diploid set contains two sets of chromosomes, one from each parent. These sets are morphologically similar except for the sex chromosomes (X and Y).

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Where is genetic material (DNA or RNA) found?

Genetic material (DNA or RNA) is located within the chromosome and its contents remain relatively constant between generations.

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How do chromosomes ensure the continuity of genetic information?

Chromosomes replicate their DNA molecule and this information is transcribed into RNA, which directs the synthesis of proteins, ultimately shaping the offspring.

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What is a metacentric chromosome?

A metacentric chromosome has a centromere located exactly in the middle, resulting in two equal arms. It forms a 'V' shape during anaphase.

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What is a submetacentric chromosome?

A submetacentric chromosome has a centromere slightly off-center, resulting in one arm longer than the other. It forms a 'J' or 'L' shape during anaphase.

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What is an acrocentric chromosome?

An acrocentric chromosome has a centromere near one end, leading to a very short arm and a very long arm. It forms a 'J' or rod shape during anaphase.

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What is a telocentric chromosome?

A telocentric chromosome has a centromere at one end, resulting in only one arm. It forms an 'I' or rod shape during anaphase.

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Heterochromatin

Highly condensed, tightly packed form of DNA found in eukaryotic cells. It is transcriptionally inactive, meaning genes within it are not expressed.

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Constitutive Heterochromatin

A type of Heterochromatin that is always tightly packed and inactive, regardless of the cell's stage or function.

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Facultative Heterochromatin

A type of Heterochromatin that can switch between active and inactive states depending on the cell's needs and developmental stage.

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Heteropycnosis

The difference in condensation levels between euchromatin and heterochromatin, visible as variations in density under a microscope.

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Replicative Timing of Heterochromatin

Heterochromatin replicates later in the cell cycle compared to euchromatin. This is due to its tight packing, which makes it harder to access for replication enzymes.

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Replicative Timing of Euchromatin

Euchromatin replicates earlier in the cell cycle compared to heterochromatin. This is due to its looser packing, making it easier to access for replication enzymes.

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Matrix and Pellicle

Non-genetic components of chromosomes that appear only at metaphase. Matrix surrounds the chromatids, while pellicle encloses the matrix.

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Study Notes

PBG 212 Classical and Molecular Cytogenetics

  • Definition: Brief history of genetics and cytogenetics
  • Cell Division: Mitosis and meiosis - significance
  • Chromosome Structure: Chromatid, chromomeres, centromere, telomere, secondary constriction, nucleolar organiser region, satellite
  • Chromatin: Chemical composition, Chromosome landmarks - Euchromatin and heterochromatin, centromere, bands, chromosome ends, knobs
  • Chromosome Types: Classified based on centromere position, number of centromeres, shape at anaphase, structure, appearance, essentiality, and role in sex determination
  • Special Chromosomes: Polytene and lampbrush chromosomes, other types - B, ring, and isochromosomes
  • Chromosome Staining: Q banding, G banding, R banding, and C banding
  • FISH: Steps in FISH, applications, and limitations
  • Mid-semester Examination

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