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Questions and Answers
What is the function of chromosomes in heredity?
What is the function of chromosomes in heredity?
- They act as structural components of the cell.
- They produce energy for cellular activities.
- They link generations through the transmission of genetic material. (correct)
- They store nutrients needed for cell growth.
Which type of chromosome has its centromere located at the center?
Which type of chromosome has its centromere located at the center?
- Acrocentric
- Metacentric (correct)
- Telocentric
- Submetacentric
Which chromosome type has unequal arm lengths due to the position of its centromere?
Which chromosome type has unequal arm lengths due to the position of its centromere?
- Submetacentric (correct)
- Metacentric
- Telocentric
- Acrocentric
What shape do metacentric chromosomes assume during anaphase?
What shape do metacentric chromosomes assume during anaphase?
What type of chromosomes do humans lack?
What type of chromosomes do humans lack?
Which chromosome types are classified as acrocentric in humans?
Which chromosome types are classified as acrocentric in humans?
During what process are chromosomes instrumental in directing protein synthesis?
During what process are chromosomes instrumental in directing protein synthesis?
What does the genetic material within chromosomes primarily consist of?
What does the genetic material within chromosomes primarily consist of?
What does a karyotype represent?
What does a karyotype represent?
Which of the following is a characteristic of an asymmetric karyotype?
Which of the following is a characteristic of an asymmetric karyotype?
What is an idiogram?
What is an idiogram?
Which statement is true regarding symmetric karyotype?
Which statement is true regarding symmetric karyotype?
What aspect of chromosomes is considered in the study of karyotype?
What aspect of chromosomes is considered in the study of karyotype?
Which karyotype type is believed to represent a primitive state?
Which karyotype type is believed to represent a primitive state?
How are chromosomes organized in an idiogram?
How are chromosomes organized in an idiogram?
What determines the genetic identity of a karyotype?
What determines the genetic identity of a karyotype?
What role do non-genetic RNAs play in cellular organisms?
What role do non-genetic RNAs play in cellular organisms?
Which amino acids are predominantly found in histones?
Which amino acids are predominantly found in histones?
In what ratio are the five types of histones generally present in eukaryotic chromosomes?
In what ratio are the five types of histones generally present in eukaryotic chromosomes?
What is the primary function of histones in relation to DNA?
What is the primary function of histones in relation to DNA?
How are non-histone proteins different from histones?
How are non-histone proteins different from histones?
What is the composition of chromatin in eukaryotic cells?
What is the composition of chromatin in eukaryotic cells?
What is a unique characteristic of the histones found in sperm cells of certain eukaryotes?
What is a unique characteristic of the histones found in sperm cells of certain eukaryotes?
Which type of protein is NOT present in lower proportions compared to histones?
Which type of protein is NOT present in lower proportions compared to histones?
What is the primary purpose of C-banding in chromosome analysis?
What is the primary purpose of C-banding in chromosome analysis?
Which staining method produces a pattern that is the opposite of G-banding?
Which staining method produces a pattern that is the opposite of G-banding?
How does the T-banding technique differ from C-banding?
How does the T-banding technique differ from C-banding?
What does a normal human karyotype indicate?
What does a normal human karyotype indicate?
Which of the following characteristics is NOT typically observed when comparing karyotypes?
Which of the following characteristics is NOT typically observed when comparing karyotypes?
Why are white blood cells commonly used for karyotyping?
Why are white blood cells commonly used for karyotyping?
What may lead to developmental abnormalities in humans?
What may lead to developmental abnormalities in humans?
Which factor can lead to differences in the relative size of chromosomes?
Which factor can lead to differences in the relative size of chromosomes?
What defines a bisexual flower?
What defines a bisexual flower?
Which of the following statements about unisexual flowers is true?
Which of the following statements about unisexual flowers is true?
What is autogamy in the context of bisexual flowers?
What is autogamy in the context of bisexual flowers?
Which process involves pollination between different flowers on the same plant?
Which process involves pollination between different flowers on the same plant?
What is the primary role of heterochromatin in the cell?
What is the primary role of heterochromatin in the cell?
What characteristic distinguishes bisexual flowers from unisexual flowers?
What characteristic distinguishes bisexual flowers from unisexual flowers?
Which type of pollination occurs before the flower opens?
Which type of pollination occurs before the flower opens?
Which type of chromatin is found towards the periphery of the nucleus?
Which type of chromatin is found towards the periphery of the nucleus?
Which flower type can produce genetically identical offspring through self-pollination?
Which flower type can produce genetically identical offspring through self-pollination?
Which statement is true about euchromatin compared to heterochromatin?
Which statement is true about euchromatin compared to heterochromatin?
What is true about monoecious plants?
What is true about monoecious plants?
What is the main difference in the replication timing between euchromatin and heterochromatin?
What is the main difference in the replication timing between euchromatin and heterochromatin?
Which of the following best describes the forms of heterochromatin?
Which of the following best describes the forms of heterochromatin?
During which phase of the cell cycle do the matrix and pellicle appear?
During which phase of the cell cycle do the matrix and pellicle appear?
What characterizes the genetic processes that affect euchromatin?
What characterizes the genetic processes that affect euchromatin?
What type of chromatin does not exhibit heteropycnosis?
What type of chromatin does not exhibit heteropycnosis?
Flashcards
Non-genetic RNA
Non-genetic RNA
RNA molecules in cellular organisms that don't carry genetic information. They perform various cellular functions under genetic control.
Histones
Histones
Basic proteins found in eukaryotic cells. They bind to DNA, helping to package it into chromatin.
Chromatin
Chromatin
The complex of DNA and proteins (histones and non-histones) that forms the building blocks of chromosomes.
Nucleosome
Nucleosome
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Types of Histones
Types of Histones
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Non-histone proteins
Non-histone proteins
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Protamines
Protamines
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Functions of non-histone proteins
Functions of non-histone proteins
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What is a karyotype?
What is a karyotype?
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What is special about a karyotype for a particular species?
What is special about a karyotype for a particular species?
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How do karyotypes help us understand evolution?
How do karyotypes help us understand evolution?
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What is an asymmetric karyotype?
What is an asymmetric karyotype?
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What is a symmetric karyotype?
What is a symmetric karyotype?
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What is an idiogram?
What is an idiogram?
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What is the significance of an idiogram?
What is the significance of an idiogram?
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How are chromosomes arranged in an idiogram?
How are chromosomes arranged in an idiogram?
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R-banding
R-banding
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C-banding
C-banding
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NOR staining
NOR staining
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T-banding
T-banding
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Karyotype
Karyotype
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Translocation
Translocation
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Segmental Interchange
Segmental Interchange
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Dislocation Hypothesis
Dislocation Hypothesis
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Homologous Chromosomes
Homologous Chromosomes
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Partially Homologous Chromosomes
Partially Homologous Chromosomes
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Bisexual Flower
Bisexual Flower
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Unisexual Flower
Unisexual Flower
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Monoecious Plant
Monoecious Plant
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Autogamy
Autogamy
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Geitonogamy
Geitonogamy
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Cleistogamy
Cleistogamy
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What makes chromosomes the organs of heredity?
What makes chromosomes the organs of heredity?
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What is a diploid chromosome set?
What is a diploid chromosome set?
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Where is genetic material (DNA or RNA) found?
Where is genetic material (DNA or RNA) found?
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How do chromosomes ensure the continuity of genetic information?
How do chromosomes ensure the continuity of genetic information?
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What is a metacentric chromosome?
What is a metacentric chromosome?
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What is a submetacentric chromosome?
What is a submetacentric chromosome?
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What is an acrocentric chromosome?
What is an acrocentric chromosome?
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What is a telocentric chromosome?
What is a telocentric chromosome?
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Heterochromatin
Heterochromatin
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Constitutive Heterochromatin
Constitutive Heterochromatin
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Facultative Heterochromatin
Facultative Heterochromatin
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Heteropycnosis
Heteropycnosis
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Replicative Timing of Heterochromatin
Replicative Timing of Heterochromatin
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Replicative Timing of Euchromatin
Replicative Timing of Euchromatin
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Matrix and Pellicle
Matrix and Pellicle
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Study Notes
PBG 212 Classical and Molecular Cytogenetics
- Definition: Brief history of genetics and cytogenetics
- Cell Division: Mitosis and meiosis - significance
- Chromosome Structure: Chromatid, chromomeres, centromere, telomere, secondary constriction, nucleolar organiser region, satellite
- Chromatin: Chemical composition, Chromosome landmarks - Euchromatin and heterochromatin, centromere, bands, chromosome ends, knobs
- Chromosome Types: Classified based on centromere position, number of centromeres, shape at anaphase, structure, appearance, essentiality, and role in sex determination
- Special Chromosomes: Polytene and lampbrush chromosomes, other types - B, ring, and isochromosomes
- Chromosome Staining: Q banding, G banding, R banding, and C banding
- FISH: Steps in FISH, applications, and limitations
- Mid-semester Examination
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