Cholinergic Receptors Overview

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Questions and Answers

What type of receptor responds to muscarins and acetylcholine?

  • Nicotinic Receptor
  • M2 Receptor
  • NN Receptor
  • Muscarinic Receptor (correct)

Which cholinergic receptor is associated with the heart?

  • M1 Receptor
  • NN Receptor
  • M2 Receptor (correct)
  • NM Receptor

What is the primary function of NM receptors?

  • Secretion of epinephrine
  • Contraction of smooth muscle
  • Contraction of skeletal muscle (correct)
  • Regulation of glandular function

Which receptor type is linked to secretion of epinephrine?

<p>NN Receptor (C)</p> Signup and view all the answers

Which cholinergic receptor type responds to nicotine?

<p>Nicotinic Receptor (D)</p> Signup and view all the answers

Flashcards

Muscarinic Receptors

Cholinergic receptors that respond to muscarine and acetylcholine. They are further divided into subtypes (M1, M2, M3) affecting different tissues.

M1 Muscarinic Receptors

Type of muscarinic receptor located on nerve endings.

M2 Muscarinic Receptors

Type of muscarinic receptor found in the heart and some nerve endings.

M3 Muscarinic Receptors

Type of muscarinic receptor found in smooth muscle, glands, and endothelium.

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Nicotinic Receptors

Cholinergic receptors that respond to nicotine and acetylcholine, divided into types NN and NM.

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NN Nicotinic Receptor

Nicotinic receptor in autonomic ganglia, involved in epinephrine release.

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NM Nicotinic Receptor

Nicotinic receptor at neuromuscular junctions responsible for muscle contraction.

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Study Notes

Cholinergic Receptors Subdivided

  • Cholinergic receptors are divided into two types: muscarinic and nicotinic.

Muscarinic Receptors

  • Respond to muscarinic substances and acetylcholine (ACh).
  • Subtypes include:
    • M1: nerve endings
    • M2: heart and some nerve endings
    • M3: smooth muscle, glands, and endothelium

Nicotinic Receptors

  • Respond to nicotine and acetylcholine (ACh).
  • Subtypes include:
    • NN: autonomic ganglia, causing secretion of epinephrine
    • NM: neuromuscular end plate, causing contraction of skeletal muscle

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