Chapter 20 pharm

Which of the following describes the toxic effect of cholinergic drugs?

Which cholinergic drug is used to treat excessively dry mouth?

What is the antidote to cholinergic drugs?

What is the function of cholinergic drugs?

What does the SLUDGE acronym stand for in the context of cholinergic drugs?

Which drug is used to relax the sphincter in the bladder, allowing it to empty?

What is the primary function of Ginkgo according to the text?

What are the effects of cholinergic drugs on the cardiovascular system?

Which drug serves as an antidote for a severe overdose of tricyclic antidepressants?

What interactions may Ginkgo have with other medications?

Which drug is used for glaucoma and intraocular surgery?

What effect do cholinergic drugs have on the body?

Which of the following is a potential use for atropine?

What is the role of succinylcholine in general anesthesia?

Cholinergic drugs effect pupils, intestines, bladder, salivation glands, and sweat glands.

Cholinergic Drugs Overview

Cholinergic drugs can have toxic effects, leading to symptoms associated with overstimulation of the parasympathetic nervous system.
SLUDGE acronym represents Salivation, Lacrimation, Urination, Diarrhea, Gastrointestinal distress, and Emesis, highlighting common symptoms of cholinergic toxicity.

Specific Cholinergic Drug Uses

Pilocarpine is a cholinergic drug commonly used to treat excessively dry mouth (xerostomia).
Atropine may be used as an antidote in cases of cholinergic toxicity.

Functions and Effects of Cholinergic Drugs

Cholinergic drugs enhance the function of the neurotransmitter acetylcholine, promoting bodily functions related to the rest-and-digest response.
They affect multiple systems, resulting in increased salivation, lacrimation, urination, digestive activity, and secretion of sweat.

Cardiovascular Effects

Cholinergic drugs generally lead to a decrease in heart rate and may cause vasodilation, influencing blood pressure.

Bladder Mechanisms

Oxybutynin is used to relax the bladder sphincter, facilitating bladder emptying.

Ginkgo Biloba Insights

Ginkgo is primarily used to enhance cognitive function and circulation.
It may interact with anticoagulants, antiplatelet drugs, and other medications affecting coagulation.

Other Relevant Drugs

Physostigmine can act as an antidote for severe overdoses of tricyclic antidepressants, reversing anticholinergic effects.
Acetylcholine analogs such as pilocarpine are utilized in the management of glaucoma and during intraocular surgeries.

Anesthesia Context

Succinylcholine is a neuromuscular blocker employed in general anesthesia to induce muscle relaxation for surgical procedures.

Conclusion

Understanding the diverse effects and applications of cholinergic drugs is crucial for effective medical treatment and management of associated symptoms.

Test your knowledge about cholinergic drugs, their effects on various body systems, toxic effects, and the antidote to cholinergic drugs. Explore indications for cholinergic drugs and their impact on bodily functions.