17 Questions
What is the main mechanism of action of aldehydes such as glutaraldehyde and OPA?
Inhibition of DNA, RNA, and other macromolecules
What is the primary advantage of using OPA over glutaraldehyde?
OPA is less toxic
Which of the following is NOT a characteristic of alcohols?
Effective in the absence of water
What is the optimal concentration range for alcohol disinfectants?
60-80%
Which of the following microorganisms is killed in 10 seconds by a concentration of 30-100% ethanol?
Pseudomonas aeruginosa
What is the primary advantage of using hydrogen peroxide as a disinfectant?
It is non-corrosive and safe on plastics
What percentage of chlorhexidine gluconate is used in high risk applications such as hospital surgical scrubs?
0.5% to 4%
What is the spectrum of activity of biguanides against Gram-positive and Gram-negative bacteria?
Rapid action against Gram-positive and Gram-negative bacteria
What is a disadvantage of using hypochlorites as disinfectants?
They can cause oropharyngeal, esophageal and gastric burns
What should cleaning personnel use when handling some disinfectants to prevent occupational exposure?
Personal Protective Equipment (PPE)
What is a type of chlorine compound that is commonly used as a disinfectant?
Sodium Hypochlorite
What is the percentage of sodium hypochlorite usually found in household bleach?
5.25% - 6.15%
What is the level of effectiveness against Liphophilic viruses like herpes, vaccinia, and influenza?
60-95%
What viruses show variable efficacy against alcohol-based disinfectants?
Non-enveloped viruses
What is the main disadvantage associated with repeated use of alcohol-based disinfectants on skin and surfaces?
Irritation, drying, and surface damage
What ligand is contained in Biguanides?
C2H7N5
What is a notable advantage of alcohol-based disinfectants for compatibility with skin?
Good compatibility with skin
Test your knowledge on the uses and formulations of Chlorhexidine Gluconate (CHG) in healthcare settings, including antimicrobial soaps, surgical scrubs, hand washes, and more. Learn about its spectrum of activity against different types of bacteria.
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