Pharm chapter 33 Chemotherapy and Nausea Management
37 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

A patient is receiving chemotherapy with cisplatin and experiencing severe nausea and vomiting. Which medication is most effective in preventing this adverse effect?

  • Diphenhydramine
  • Meclizine
  • Ondansetron (correct)
  • Prochlorperazine (Compazine)
  • Which medication class is primarily responsible for preventing motion sickness?

  • Serotonin antagonists
  • Anticholinergics (correct)
  • Corticosteroids
  • Phenothiazines
  • A patient is receiving chemotherapy with cisplatin and experiencing severe nausea and vomiting. Which administration route of ondansetron is most effective?

  • Intravenous (correct)
  • Transdermal
  • Subcutaneous
  • Oral
  • Which of the following is a reason to administer metoclopramide (Reglan) postoperatively?

    <p>Prevent postoperative nausea and vomiting (B)</p> Signup and view all the answers

    Which medication is used to treat mild to moderate nausea and vomiting associated with anesthesia and surgery?

    <p>Phenothiazines (A)</p> Signup and view all the answers

    What is the primary mechanism of action of metoclopramide (Reglan) in preventing nausea and vomiting?

    <p>Increasing sphincter tone in the gastrointestinal tract (C)</p> Signup and view all the answers

    Which medication class is used to treat nausea and vomiting related to pregnancy, postsurgical state, chemotherapy, and bowel obstruction?

    <p>Corticosteroids (A)</p> Signup and view all the answers

    A patient is experiencing severe, chemotherapy-induced nausea and vomiting (CINV). Which medication should be administered for the best chance of preventing further episodes?

    <p>Ondansetron 1 hour before chemotherapy and for 4 days after (D)</p> Signup and view all the answers

    Which positioning technique is effective for children suffering from motion sickness?

    <p>Blocking out scenery through the side windows. (B)</p> Signup and view all the answers

    What is a misconception regarding motion sickness in children?

    <p>There is no such thing as car sickness. (B)</p> Signup and view all the answers

    When discussing nausea and vomiting during pregnancy, which statement is true?

    <p>Nausea and vomiting can occur at any time of the day. (D)</p> Signup and view all the answers

    Which factor increases the likelihood of nausea and vomiting during pregnancy?

    <p>Being a primigravida. (A)</p> Signup and view all the answers

    Which of the following statements about treating vomiting in young children is accurate?

    <p>Consulting a healthcare provider for dosage is important. (D)</p> Signup and view all the answers

    What is the primary role of benzodiazepines in relation to chemotherapy?

    <p>They reduce the frequency of nausea and vomiting, and alleviate anxiety. (B)</p> Signup and view all the answers

    What condition is characterized by nausea experienced immediately upon entering a chemotherapy clinic?

    <p>Anticipatory nausea and vomiting (D)</p> Signup and view all the answers

    Which herb is commonly used across many cultures to relieve nausea associated with pregnancy?

    <p>Ginger (B)</p> Signup and view all the answers

    When a patient is taking a cannabinoid during chemotherapy, what important consideration should the nurse keep in mind?

    <p>Antihistamines may increase the effects of cannabinoids. (D)</p> Signup and view all the answers

    What is the time frame for delayed emesis to occur after chemotherapy administration?

    <p>24 to 120 hours (A)</p> Signup and view all the answers

    What is the likely cause of a patient's nausea triggered by seeing or smelling the clinic prior to receiving chemotherapy?

    <p>Anticipatory nausea and vomiting (D)</p> Signup and view all the answers

    Which of the following substances is known to potentially interact with the effects of cannabinoids?

    <p>Benzodiazepines (D)</p> Signup and view all the answers

    Which statement about the use of benzodiazepines during chemotherapy is false?

    <p>They are primarily used for distraction techniques. (D)</p> Signup and view all the answers

    Which patient is most likely to experience postoperative nausea and vomiting (PONV)?

    <p>A 50-year-old woman undergoing a total hysterectomy with general anesthesia (A)</p> Signup and view all the answers

    Which medication is associated with the lowest risk of adverse reactions?

    <p>Dexamethasone (C)</p> Signup and view all the answers

    What role does the chemoreceptor trigger zone (CTZ) play in the vomiting process?

    <p>Activates the vomit center to induce vomiting (B), Samples blood and spinal fluid for potentially toxic substances (D)</p> Signup and view all the answers

    Why is drug therapy important for managing nausea and vomiting?

    <p>Prevents aspiration of gastric contents into the lung (A), Prevents dehydration (B), Relieves the distress associated with nausea and vomiting (D)</p> Signup and view all the answers

    Which of the following patients would be least likely to experience nausea and vomiting after surgery?

    <p>An 80-year-old man with spinal anesthesia (B), A 5-year-old child with regional anesthesia (C)</p> Signup and view all the answers

    What autonomic symptoms are typically observed with vomiting?

    <p>Pallor, sweating, and tachycardia (B)</p> Signup and view all the answers

    Which statement about PONV in children is accurate?

    <p>Young children generally have lower risks of PONV compared to adults. (A)</p> Signup and view all the answers

    What is the primary reason why hydration is important in patients experiencing vomiting?

    <p>It supports proper electrolyte balance. (C)</p> Signup and view all the answers

    Which medication is the preferred choice for treating hyperemesis gravidarum?

    <p>Metoclopramide (Reglan) (A)</p> Signup and view all the answers

    In which scenario is dexamethasone primarily used?

    <p>As an effective medication for postoperative nausea and vomiting (B)</p> Signup and view all the answers

    Why does the nurse monitor daily weights before administering antiemetic medications to chemotherapy patients?

    <p>Weight loss is a common adverse effect associated with chemotherapy, and dosages may need to be readjusted. (B)</p> Signup and view all the answers

    What is a key advantage of using benzodiazepines in nausea and vomiting treatments for chemotherapy patients?

    <p>The long half-life will prolong the effectiveness of other drugs (C)</p> Signup and view all the answers

    Which of the following is NOT an autonomic symptom associated with vomiting?

    <p>Diarrhea (A)</p> Signup and view all the answers

    How does maintaining daily weight records benefit the management of chemotherapy patients?

    <p>It assists in adjusting antiemetic dosages as needed. (C)</p> Signup and view all the answers

    Which of the following statements about the effects of metoclopramide is accurate?

    <p>Metoclopramide can be safely used in treating hyperemesis gravidarum. (B)</p> Signup and view all the answers

    Which symptom is unlikely to be monitored for relation to vomiting?

    <p>Urinary urgency (D)</p> Signup and view all the answers

    Flashcards

    Positioning Techniques for Motion Sickness

    Methods like facing forward and blocking views can help children with motion sickness.

    Motion Sickness Reality

    Motion sickness is a legitimate condition, not a myth or made-up issue.

    Benadryl Use for Nausea

    Benadryl is not effective for treating nausea or vomiting in children.

    Hyperemesis Gravidarum

    Severe, persistent vomiting during pregnancy, needing medical attention.

    Signup and view all the flashcards

    Nausea Timing in Pregnancy

    Nausea and vomiting can occur at any time during pregnancy, not just mornings.

    Signup and view all the flashcards

    Antianxiety Effect

    Reduces frequency of anxiety, nausea, and vomiting, especially during chemotherapy.

    Signup and view all the flashcards

    Benzodiazepines

    Medications (e.g., diazepam, lorazepam) that reduce anxiety and nausea without affecting other drugs' effectiveness.

    Signup and view all the flashcards

    Anticipatory Nausea and Vomiting (ANV)

    A conditioned response of nausea triggered by sight or smell related to chemotherapy.

    Signup and view all the flashcards

    Delayed Emesis

    Nausea and vomiting that occurs 24 to 120 hours after chemotherapy administration.

    Signup and view all the flashcards

    Ginger for Nausea

    A herb widely used for relief of pregnancy-induced nausea and vomiting.

    Signup and view all the flashcards

    Cannabinoid Considerations

    Nurses must monitor interactions, particularly with antihistamines which may increase toxicity during chemotherapy.

    Signup and view all the flashcards

    No Dietary Restrictions with Cannabinoids

    Patients using cannabinoids need no specific dietary restrictions related to potassium or other foods.

    Signup and view all the flashcards

    CINV Prevention

    The approach to prevent severe chemotherapy-induced nausea and vomiting, especially after administering emetogenic drugs like cisplatin.

    Signup and view all the flashcards

    Ondansetron

    An antiemetic medication effective for preventing nausea and vomiting caused by chemotherapy, especially cisplatin.

    Signup and view all the flashcards

    Prochlorperazine

    A medication used to treat mild to moderate nausea and vomiting, but not recommended for CINV.

    Signup and view all the flashcards

    Anticholinergic Agents

    Medications such as diphenhydramine and meclizine used to treat motion sickness by countering acetylcholine.

    Signup and view all the flashcards

    Metoclopramide (Reglan)

    An antiemetic that prevents postoperative nausea and vomiting by acting on dopamine and serotonin receptors.

    Signup and view all the flashcards

    Motion Sickness Prevention

    The use of anticholinergic agents to counteract nausea during travel or movement.

    Signup and view all the flashcards

    Corticosteroids for Nausea

    Used to treat nausea and vomiting in various situations like pregnancy, post-surgery, and chemotherapy.

    Signup and view all the flashcards

    Dopamine Receptor Antagonist

    A class of drugs like metoclopramide that helps reduce nausea by blocking dopamine receptors in the brain.

    Signup and view all the flashcards

    Autonomic Symptoms of Vomiting

    Pallor, sweating, and tachycardia often accompany vomiting.

    Signup and view all the flashcards

    Metoclopramide

    Drug of choice for hyperemesis gravidarum with no teratogenic effects.

    Signup and view all the flashcards

    Daily Weights for Chemotherapy Patients

    Monitoring daily weights helps adjust antiemetic dosages due to weight loss.

    Signup and view all the flashcards

    Effects of Chemotherapy

    Nausea and vomiting lead to weight loss in patients undergoing chemotherapy.

    Signup and view all the flashcards

    Benzodiazepines for Nausea and Vomiting

    Used as adjunctive therapy to enhance effectiveness of other antiemetics.

    Signup and view all the flashcards

    THC (Marinol)

    Used for nausea and vomiting related to cancer treatment.

    Signup and view all the flashcards

    Haloperidol (Haldol)

    Used for severe nausea associated with chemotherapy.

    Signup and view all the flashcards

    Dexamethasone

    A corticosteroid used for nausea in various conditions including pregnancy.

    Signup and view all the flashcards

    Postoperative Nausea and Vomiting (PONV)

    A common complication following surgery, especially after general anesthesia.

    Signup and view all the flashcards

    PONV Risk Factors

    Factors that increase the chance of experiencing PONV, such as gender, age, and anesthesia type.

    Signup and view all the flashcards

    Chemoreceptor Trigger Zone (CTZ)

    Brain region that samples toxins and activates the vomiting center.

    Signup and view all the flashcards

    Drug Therapy for Nausea

    Medication aimed to relieve nausea and prevent complications such as dehydration and aspiration.

    Signup and view all the flashcards

    Spinal Anesthesia

    A type of anesthesia that is generally least likely to cause PONV.

    Signup and view all the flashcards

    Adverse Effects of Antiemetics

    Side effects associated with anti-nausea medications like ondansetron and promethazine.

    Signup and view all the flashcards

    Study Notes

    Chemotherapy-Induced Nausea and Vomiting (CINV)

    • Cisplatin is a chemotherapy drug that often causes severe nausea and vomiting.
    • Ondansetron is a medication most effective for preventing CINV caused by cisplatin.
    • Anticholinergic agents, like diphenhydramine or meclizine, are not as effective as ondansetron for preventing CINV from cisplatin.
    • Prochlorperazine is not the best treatment for preventing chemotherapy-induced nausea and vomiting.
    • Metoclopramide (Reglan) is an antiemetic used to prevent postoperative nausea and vomiting.
    • Metoclopramide works by increasing gastrointestinal motility.

    Motion Sickness

    • Anticholinergics are the most effective treatment for motion sickness.
    • Serotonin antagonists are used to treat nausea and vomiting associated with cancer chemotherapy, radiation therapy, and postoperative procedures.

    Postoperative Nausea and Vomiting (PONV)

    • Metoclopramide is effective in preventing PONV.
    • Metoclopramide acts on dopamine and serotonin receptors in the brain and gastrointestinal tract.
    • Metoclopramide increases sphincter tone in the gastrointestinal tract.

    Hyperemesis Gravidarum

    • Metoclopramide is the drug of choice to treat hyperemesis gravidarum.

    Managing Nausea and Vomiting in Chemotherapy Patients

    • Daily monitoring of weight is important in chemotherapy patients, as weight loss can necessitate dosage adjustments for antiemetic medications.
    • Antihistamines, alcohol, analgesics, benzodiazepines, and other drugs can increase the risk of toxic effects when combined with antiemetics.

    Anticipatory Nausea and Vomiting

    • Anticipatory nausea and vomiting can be triggered by the sight or smell of the clinic or hospital.
    • Anticipatory nausea and vomiting is a conditioned response.
    • Delayed emesis can occur 24–120 hours after chemotherapy treatment.

    Considerations for Pediatric Patients

    • Positioning techniques, such as having the child face forward and blocking out the scenery, can be helpful for car sickness in young children.
    • Over-the-counter medication should be used with caution in young children.

    Herbs for Nausea Relief

    • Ginger has traditionally been used to treat pregnancy-induced nausea.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Pharm Chapter 33 PDF

    Description

    This quiz covers key concepts relating to chemotherapy-induced nausea and vomiting (CINV), motion sickness, and postoperative nausea and vomiting (PONV). Explore how different medications, such as ondansetron and metoclopramide, are used to manage these conditions effectively. Test your understanding of the pharmacological interventions for nausea and vomiting in various medical contexts.

    More Like This

    Quiz
    36 questions

    Quiz

    ComfortingClarity avatar
    ComfortingClarity
    Use Quizgecko on...
    Browser
    Browser