Chemotherapeutics Quiz

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Questions and Answers

Which class of drugs binds to tubulin in cells and disrupts the mitotic spindle?

  • Anti Metabolites
  • Anti tumour antibiotics (correct)
  • Alkylating Agents
  • Platinum analogues

Which class of drugs inhibits the use of cell metabolites used in growth and cell division?

  • Alkylating Agents
  • Anti tumour antibiotics
  • Platinum analogues
  • Anti Metabolites (correct)

Which class of drugs inhibits various TK receptors, such as KIT and VEGFR?

  • Anti tumour antibiotics
  • Tyrosine kinase inhibitors (correct)
  • Anti Metabolites
  • Alkylating Agents

Which class of drugs binds platinum to DNA causing cross linkage and cell death?

<p>Platinum analogues (B)</p> Signup and view all the answers

Which class of drugs inhibits topoisomerase-II causing breakage of DNA and cell death?

<p>Anti tumour antibiotics (D)</p> Signup and view all the answers

Which class of drugs binds to and cross-links DNA?

<p>Alkylating Agents (D)</p> Signup and view all the answers

Which route of administration is not helpful for vets when using chemotherapeutic agents?

<p>Topical (D)</p> Signup and view all the answers

Which type of treatment involves the use of chemotherapeutic drugs along with radiography and/or surgery?

<p>Adjuvant treatment (C)</p> Signup and view all the answers

What is the definition of a chemotherapeutic agent?

<p>A drug used to treat cancers by causing cell death or stopping cells from dividing (C)</p> Signup and view all the answers

What is the specific definition of chemotherapy in most first opinion practices?

<p>The use of chemotherapeutic agents to treat cancers (C)</p> Signup and view all the answers

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

<p>To cause cell death or stop cell division (D)</p> Signup and view all the answers

Which type of tumours should be treated with a high growth fraction?

<p>Tumours with high growth fraction (B)</p> Signup and view all the answers

What is the purpose of using cell cycle specific drugs?

<p>To target a limited number of cells with each dose (C)</p> Signup and view all the answers

Why is it important to use combinations of drugs in chemotherapy?

<p>To target cancer cells in different phases of the cell cycle (A)</p> Signup and view all the answers

How should quality of life be maintained during chemotherapy?

<p>By assessing the side effects of chemotherapy (D)</p> Signup and view all the answers

What can chemotherapy drugs do to people who come into direct contact with them?

<p>Cause adverse effects (D)</p> Signup and view all the answers

What is the purpose of using antiemetic drugs during chemotherapy?

<p>To treat symptoms of nausea and vomiting (A)</p> Signup and view all the answers

How do we know when to start treatment for small tumours?

<p>By monitoring the tumour growth rate (A)</p> Signup and view all the answers

Which class of drugs is known for causing peripheral neuropathy as an adverse event?

<p>Plant Alkaloids (B)</p> Signup and view all the answers

Which class of drugs is associated with cumulative cardiotoxicity in dogs and nephrotoxicity in cats?

<p>Anti tumour antibiotics (A)</p> Signup and view all the answers

Which class of drugs is used to treat lymphoma with CNS involvement?

<p>Anti Metabolites (B)</p> Signup and view all the answers

Which class of drugs is used to treat osteosarcoma and carcinomas?

<p>Platinum analogues (B)</p> Signup and view all the answers

Which class of drugs is used to inhibit various TK receptors, such as KIT and VEGFR?

<p>Tyrosine kinase inhibitors (B)</p> Signup and view all the answers

Which route of administration is not recommended for vets when using chemotherapeutic agents?

<p>Topical (D)</p> Signup and view all the answers

Which type of treatment involves the use of chemotherapeutic drugs along with radiography and/or surgery?

<p>Adjuvant treatment (D)</p> Signup and view all the answers

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

<p>To stop cell division (A)</p> Signup and view all the answers

What types of chemotherapeutic agents do vets primarily use?

<p>Cytotoxic drugs (C)</p> Signup and view all the answers

What is the specific definition of a chemotherapeutic agent in most first opinion practices?

<p>A drug used to treat cancers by causing cell death or stopping cell division (A)</p> Signup and view all the answers

What do cytotoxic drugs primarily do as chemotherapeutic agents?

<p>Inhibit mitosis and/or damage DNA (B)</p> Signup and view all the answers

Which type of cells are targeted when treating small tumors with a high growth fraction?

<p>Rapidly dividing cells (B)</p> Signup and view all the answers

What is the recommended approach for dosing cell cycle specific drugs?

<p>Repeat dosing as often as possible (D)</p> Signup and view all the answers

Why is it important to use combinations of drugs in chemotherapy?

<p>To target different phases of the cell cycle (A)</p> Signup and view all the answers

What is the purpose of using antiemetic drugs during chemotherapy?

<p>To treat adverse effects like nausea and vomiting (C)</p> Signup and view all the answers

How should quality of life be maintained during chemotherapy?

<p>By effectively communicating with owners (B)</p> Signup and view all the answers

What can chemotherapy drugs do to people who come into direct contact with them?

<p>Cause direct exposure to the drugs (A)</p> Signup and view all the answers

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

<p>To target and kill cancer cells (D)</p> Signup and view all the answers

Which class of drugs inhibits various TK receptors, such as KIT and VEGFR?

<p>Tyrosine kinase inhibitors (B)</p> Signup and view all the answers

What is the definition of a chemotherapeutic agent?

<p>A chemotherapeutic agent is a drug used to treat cancers by causing cell death or stopping cells from dividing.</p> Signup and view all the answers

How are chemotherapeutic agents used?

<p>Chemotherapeutic agents can be administered orally, by injection, by IV infusion (given slowly), or topically (though not recommended for cats and dogs).</p> Signup and view all the answers

What do cytotoxic drugs primarily do as chemotherapeutic agents?

<p>Cytotoxic drugs primarily inhibit mitosis and/or damage DNA, targeting both healthy cells and cancer cells.</p> Signup and view all the answers

What are the limitations of cytotoxic drug treatments?

<p>Palliative, not curative; toxicity limits dose or frequency of dose; maximum tolerated dose</p> Signup and view all the answers

What are the different classes of therapeutic agents used by vets?

<p>Alkylating Agents, Plant Alkaloids, Anti Metabolites, Anti tumour antibiotics, Platinum analogues, Tyrosine kinase inhibitors</p> Signup and view all the answers

What are the adverse events associated with the use of anti tumour antibiotics?

<p>Myelosuppression, GI signs, Extreme irritation if leaks from vein, Alopecia, Cumulative cardiotoxicity (dogs), Nephrotoxic (cats)</p> Signup and view all the answers

What are some strategies for maximizing the benefit of chemotherapy treatment for small tumors with a high growth fraction?

<p>Repeat dosing as often as possible and use combinations of drugs to target different phases and work in different ways.</p> Signup and view all the answers

How can the harm of chemotherapy treatment be minimized?

<p>By being aware of adverse effects and providing symptomatic treatment, monitoring the patient, and communicating with owners.</p> Signup and view all the answers

What is the importance of maintaining quality of life during chemotherapy treatment?

<p>Quality of life must be maintained to ensure the well-being of the patient.</p> Signup and view all the answers

How can chemotherapeutic drugs potentially affect people who come into contact with them?

<p>Chemotherapeutic drugs can potentially enhance people either through direct exposure to the drugs or metabolites excreted by the pets.</p> Signup and view all the answers

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