Chemotherapeutics Quiz

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Which class of drugs binds to tubulin in cells and disrupts the mitotic spindle?

Anti Metabolites

Anti tumour antibiotics (correct)

Alkylating Agents

Platinum analogues

Which class of drugs inhibits the use of cell metabolites used in growth and cell division?

Alkylating Agents

Anti tumour antibiotics

Platinum analogues

Anti Metabolites (correct)

Which class of drugs inhibits various TK receptors, such as KIT and VEGFR?

Anti tumour antibiotics

Tyrosine kinase inhibitors (correct)

Anti Metabolites

Alkylating Agents

Which class of drugs binds platinum to DNA causing cross linkage and cell death?

Platinum analogues Signup and view all the answers

Which class of drugs inhibits topoisomerase-II causing breakage of DNA and cell death?

Anti tumour antibiotics Signup and view all the answers

Which class of drugs binds to and cross-links DNA?

Alkylating Agents Signup and view all the answers

Which route of administration is not helpful for vets when using chemotherapeutic agents?

Topical Signup and view all the answers

Which type of treatment involves the use of chemotherapeutic drugs along with radiography and/or surgery?

Adjuvant treatment Signup and view all the answers

What is the definition of a chemotherapeutic agent?

A drug used to treat cancers by causing cell death or stopping cells from dividing Signup and view all the answers

What is the specific definition of chemotherapy in most first opinion practices?

The use of chemotherapeutic agents to treat cancers Signup and view all the answers

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

To cause cell death or stop cell division Signup and view all the answers

Which type of tumours should be treated with a high growth fraction?

Tumours with high growth fraction Signup and view all the answers

What is the purpose of using cell cycle specific drugs?

To target a limited number of cells with each dose Signup and view all the answers

Why is it important to use combinations of drugs in chemotherapy?

To target cancer cells in different phases of the cell cycle Signup and view all the answers

How should quality of life be maintained during chemotherapy?

By assessing the side effects of chemotherapy Signup and view all the answers

What can chemotherapy drugs do to people who come into direct contact with them?

Cause adverse effects Signup and view all the answers

What is the purpose of using antiemetic drugs during chemotherapy?

To treat symptoms of nausea and vomiting Signup and view all the answers

How do we know when to start treatment for small tumours?

By monitoring the tumour growth rate Signup and view all the answers

Which class of drugs is known for causing peripheral neuropathy as an adverse event?

Plant Alkaloids Signup and view all the answers

Which class of drugs is associated with cumulative cardiotoxicity in dogs and nephrotoxicity in cats?

Anti tumour antibiotics Signup and view all the answers

Which class of drugs is used to treat lymphoma with CNS involvement?

Anti Metabolites Signup and view all the answers

Which class of drugs is used to treat osteosarcoma and carcinomas?

Platinum analogues Signup and view all the answers

Which class of drugs is used to inhibit various TK receptors, such as KIT and VEGFR?

Tyrosine kinase inhibitors Signup and view all the answers

Which route of administration is not recommended for vets when using chemotherapeutic agents?

Topical Signup and view all the answers

Which type of treatment involves the use of chemotherapeutic drugs along with radiography and/or surgery?

Adjuvant treatment Signup and view all the answers

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

To stop cell division Signup and view all the answers

What types of chemotherapeutic agents do vets primarily use?

Cytotoxic drugs Signup and view all the answers

What is the specific definition of a chemotherapeutic agent in most first opinion practices?

A drug used to treat cancers by causing cell death or stopping cell division Signup and view all the answers

What do cytotoxic drugs primarily do as chemotherapeutic agents?

Inhibit mitosis and/or damage DNA Signup and view all the answers

Which type of cells are targeted when treating small tumors with a high growth fraction?

Rapidly dividing cells Signup and view all the answers

What is the recommended approach for dosing cell cycle specific drugs?

Repeat dosing as often as possible Signup and view all the answers

Why is it important to use combinations of drugs in chemotherapy?

To target different phases of the cell cycle Signup and view all the answers

What is the purpose of using antiemetic drugs during chemotherapy?

To treat adverse effects like nausea and vomiting Signup and view all the answers

How should quality of life be maintained during chemotherapy?

By effectively communicating with owners Signup and view all the answers

What can chemotherapy drugs do to people who come into direct contact with them?

Cause direct exposure to the drugs Signup and view all the answers

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

To target and kill cancer cells Signup and view all the answers

Which class of drugs inhibits various TK receptors, such as KIT and VEGFR?

Tyrosine kinase inhibitors Signup and view all the answers

What is the definition of a chemotherapeutic agent?

A chemotherapeutic agent is a drug used to treat cancers by causing cell death or stopping cells from dividing. Signup and view all the answers

How are chemotherapeutic agents used?

Chemotherapeutic agents can be administered orally, by injection, by IV infusion (given slowly), or topically (though not recommended for cats and dogs). Signup and view all the answers

What do cytotoxic drugs primarily do as chemotherapeutic agents?

Cytotoxic drugs primarily inhibit mitosis and/or damage DNA, targeting both healthy cells and cancer cells. Signup and view all the answers

What are the limitations of cytotoxic drug treatments?

Palliative, not curative; toxicity limits dose or frequency of dose; maximum tolerated dose Signup and view all the answers

What are the different classes of therapeutic agents used by vets?

Alkylating Agents, Plant Alkaloids, Anti Metabolites, Anti tumour antibiotics, Platinum analogues, Tyrosine kinase inhibitors Signup and view all the answers

What are the adverse events associated with the use of anti tumour antibiotics?

Myelosuppression, GI signs, Extreme irritation if leaks from vein, Alopecia, Cumulative cardiotoxicity (dogs), Nephrotoxic (cats) Signup and view all the answers

What are some strategies for maximizing the benefit of chemotherapy treatment for small tumors with a high growth fraction?

Repeat dosing as often as possible and use combinations of drugs to target different phases and work in different ways. Signup and view all the answers

How can the harm of chemotherapy treatment be minimized?

By being aware of adverse effects and providing symptomatic treatment, monitoring the patient, and communicating with owners. Signup and view all the answers

What is the importance of maintaining quality of life during chemotherapy treatment?

Quality of life must be maintained to ensure the well-being of the patient. Signup and view all the answers

How can chemotherapeutic drugs potentially affect people who come into contact with them?

Chemotherapeutic drugs can potentially enhance people either through direct exposure to the drugs or metabolites excreted by the pets. Signup and view all the answers

Chemotherapeutics Quiz

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Questions and Answers

Which class of drugs binds to tubulin in cells and disrupts the mitotic spindle?

Which class of drugs inhibits the use of cell metabolites used in growth and cell division?

Which class of drugs inhibits various TK receptors, such as KIT and VEGFR?

Which class of drugs binds platinum to DNA causing cross linkage and cell death?

Which class of drugs inhibits topoisomerase-II causing breakage of DNA and cell death?

Which class of drugs binds to and cross-links DNA?

Which route of administration is not helpful for vets when using chemotherapeutic agents?

Which type of treatment involves the use of chemotherapeutic drugs along with radiography and/or surgery?

What is the definition of a chemotherapeutic agent?

What is the specific definition of chemotherapy in most first opinion practices?

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

Which type of tumours should be treated with a high growth fraction?

What is the purpose of using cell cycle specific drugs?

Why is it important to use combinations of drugs in chemotherapy?

How should quality of life be maintained during chemotherapy?

What can chemotherapy drugs do to people who come into direct contact with them?

What is the purpose of using antiemetic drugs during chemotherapy?

How do we know when to start treatment for small tumours?

Which class of drugs is known for causing peripheral neuropathy as an adverse event?

Which class of drugs is associated with cumulative cardiotoxicity in dogs and nephrotoxicity in cats?

Which class of drugs is used to treat lymphoma with CNS involvement?

Which class of drugs is used to treat osteosarcoma and carcinomas?

Which class of drugs is used to inhibit various TK receptors, such as KIT and VEGFR?

Which route of administration is not recommended for vets when using chemotherapeutic agents?

Which type of treatment involves the use of chemotherapeutic drugs along with radiography and/or surgery?

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

What types of chemotherapeutic agents do vets primarily use?

What is the specific definition of a chemotherapeutic agent in most first opinion practices?

What do cytotoxic drugs primarily do as chemotherapeutic agents?

Which type of cells are targeted when treating small tumors with a high growth fraction?

What is the recommended approach for dosing cell cycle specific drugs?

Why is it important to use combinations of drugs in chemotherapy?

What is the purpose of using antiemetic drugs during chemotherapy?

How should quality of life be maintained during chemotherapy?

What can chemotherapy drugs do to people who come into direct contact with them?

What is the main purpose of using chemotherapeutic drugs as part of treatment for lymphoma in dogs and cats?

Which class of drugs inhibits various TK receptors, such as KIT and VEGFR?

What is the definition of a chemotherapeutic agent?

How are chemotherapeutic agents used?

What do cytotoxic drugs primarily do as chemotherapeutic agents?

What are the limitations of cytotoxic drug treatments?

What are the different classes of therapeutic agents used by vets?

What are the adverse events associated with the use of anti tumour antibiotics?

What are some strategies for maximizing the benefit of chemotherapy treatment for small tumors with a high growth fraction?

How can the harm of chemotherapy treatment be minimized?

What is the importance of maintaining quality of life during chemotherapy treatment?

How can chemotherapeutic drugs potentially affect people who come into contact with them?

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