Chemical Filters in Sunscreens

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What is the primary function of Mexoryl SX in sunscreens?

To absorb UV rays and release them as thermal energy

What is the limitation of Mexoryl SX in terms of UV protection?

It doesn't protect against the entire UV spectrum

What is the main difference between Mexoryl SX and Mexoryl XL?

Mexoryl XL is used synergistically with Mexoryl SX

Why is Mexoryl SX not sufficient as a single ingredient in sunscreens?

It doesn't provide protection against the entire UV spectrum

What is the benefit of Mexoryl SX being water-soluble?

It makes it easier to formulate in sunscreens

What is the current status of Mexoryl XL in the US market?

It is not approved by the FDA

What is the primary advantage of using Mexoryl SX and Mexoryl XL together?

It provides better broad-spectrum protection

What is the patent status of Mexoryl SX?

It is patented by L'Oréal

What is the primary difference between Mexoryl SX and other chemical filters?

It is more photostable

Why is Mexoryl SX used in combination with other filters?

To provide broad-spectrum protection

Study Notes

Chemical Filters

  • Avobenzone: absorbs full UVA spectrum, oil-soluble, tends to be unstable when combined with octinoxate, but can be stabilized by octocrylene, 4-MBC, Tinosorb, Meroxyl SX, and other UV filters or photo-stabilizers.
  • Helioplex: a combination of avobenzone and oxybenzone, offering broad-spectrum protection and stability, but not water-resistant, held by Neutrogena, and FDA-approved.

Octinoxate

  • Octinoxate: absorbs UVB rays, water-insoluble, degrades over time when exposed to sunlight, can be stabilized by other UV filters such as Tinosorb M.
  • Also known as octyl methoxy-cinnamate (OMC), ethylhexyl methoxycinnamate (EHMC), and other names.

Octocrylene

  • Octocrylene: absorbs UVB and UVA2 rays, oil-soluble, absorbed by skin, can increase skin's photosensitivity to the sun, increasing free radicals.
  • Photostable and helps stabilize other UV filters.

Mexoryl SX

  • Mexoryl SX: absorbs UV rays, releases thermal energy, doesn't protect against the entire UV spectrum, and has to be combined with other filters for good protection.
  • Also known as terephthalylidene dicamphor sulfonic acid (TDSA) and ecamsule, FDA-approved.

Mexoryl XL

  • Mexoryl XL: absorbs UV rays, oil-soluble, photostable, used synergistically with Mexoryl SX, not yet FDA-approved.

This quiz covers various chemical filters used in sunscreens, their properties, and interactions. It includes active ranges, functionality, and limitations of filters like Avobenzone.

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