Podcast
Questions and Answers
What is the main focus of the current Discovery Grant project?
What is the main focus of the current Discovery Grant project?
- Surface modification of paper substrates to prevent non-specific binding of molecules (correct)
- Creating pathogen-tracking paper sensor platforms
- Funding research for Legionella detection in water towers
- Developing functional nucleic acids for bacterial detection
What is the total funding amount of the DNAPrint grant over its duration?
What is the total funding amount of the DNAPrint grant over its duration?
- $517,000
- $757,000
- $687,000 (correct)
- $229,000
Which of the following best describes the relationship between the Discovery Grant and the SPG proposal?
Which of the following best describes the relationship between the Discovery Grant and the SPG proposal?
- They have minimal conceptual overlap and no budgetary overlap. (correct)
- They have a significant budgetary overlap.
- They focus on the same materials and concepts.
- They are both aimed at developing new nanomaterials.
What specific application does the SPG proposal focus on?
What specific application does the SPG proposal focus on?
Which individuals are funded by the Discovery Grant?
Which individuals are funded by the Discovery Grant?
What is the applicant's family name?
What is the applicant's family name?
Which department is associated with the grant application?
Which department is associated with the grant application?
How many hours per month is the applicant planning to devote to the proposed research?
How many hours per month is the applicant planning to devote to the proposed research?
What is the title of the proposal submitted by the applicant?
What is the title of the proposal submitted by the applicant?
Which of the following keywords is not included in the proposal?
Which of the following keywords is not included in the proposal?
What personal identification number (PIN) is assigned to the applicant?
What personal identification number (PIN) is assigned to the applicant?
Which institution will administer the grant?
Which institution will administer the grant?
Which research subject code is identified as primary in this application?
Which research subject code is identified as primary in this application?
What is the activity time for Anbuhi Jahanshahi as stated in the document?
What is the activity time for Anbuhi Jahanshahi as stated in the document?
Which organization is associated with Amyn Sayani?
Which organization is associated with Amyn Sayani?
Who is listed as a collaborator with the Family name 'Filipe'?
Who is listed as a collaborator with the Family name 'Filipe'?
How many hours per month does Ashkar dedicate to research activities?
How many hours per month does Ashkar dedicate to research activities?
What does the PIN stand for in the context of the document?
What does the PIN stand for in the context of the document?
Which of the following individuals is not listed as a co-applicant?
Which of the following individuals is not listed as a co-applicant?
What is the relationship between GSK Canada and Amyn Sayani?
What is the relationship between GSK Canada and Amyn Sayani?
What is the full name of the organization abbreviated as NSERC?
What is the full name of the organization abbreviated as NSERC?
What is the total in-kind contribution from Advanced Theranostics?
What is the total in-kind contribution from Advanced Theranostics?
What role will Kevin Pennings have in the project?
What role will Kevin Pennings have in the project?
What percentage of fringe benefits is included in Kevin Pennings' salary?
What percentage of fringe benefits is included in Kevin Pennings' salary?
How much is Marianne Chew expected to dedicate to the project?
How much is Marianne Chew expected to dedicate to the project?
Which of the following is NOT mentioned as part of the materials and supplies budget?
Which of the following is NOT mentioned as part of the materials and supplies budget?
What is the total cost allocated for materials and supplies?
What is the total cost allocated for materials and supplies?
What is a key strength of Kevin Pennings as highlighted in the budget justification?
What is a key strength of Kevin Pennings as highlighted in the budget justification?
What funding does the organization hope to receive through their Idea to Innovation grant application?
What funding does the organization hope to receive through their Idea to Innovation grant application?
What is the total estimated value of in-kind contributions from Advanced Theranostics Inc. for salaries and equipment?
What is the total estimated value of in-kind contributions from Advanced Theranostics Inc. for salaries and equipment?
What is the primary goal of Advanced Theranostics Inc. as stated in the letter?
What is the primary goal of Advanced Theranostics Inc. as stated in the letter?
Which technology is Advanced Theranostics Inc. interested in integrating with their diagnostic systems?
Which technology is Advanced Theranostics Inc. interested in integrating with their diagnostic systems?
What is the significant characteristic of the reagent stabilization technology developed by Dr. Filipe?
What is the significant characteristic of the reagent stabilization technology developed by Dr. Filipe?
What type of diseases is Advanced Theranostics Inc. currently focusing on detecting?
What type of diseases is Advanced Theranostics Inc. currently focusing on detecting?
How long is the desired time for obtaining a test result using the new POC test device?
How long is the desired time for obtaining a test result using the new POC test device?
What has Advanced Theranostics Inc. agreed to provide for the research collaboration?
What has Advanced Theranostics Inc. agreed to provide for the research collaboration?
What is the in-kind value of research time expected from Advanced Theranostics Inc.?
What is the in-kind value of research time expected from Advanced Theranostics Inc.?
What is a key benefit of moving to a capsule/tablet format for vaccines?
What is a key benefit of moving to a capsule/tablet format for vaccines?
Which of the following methods can the technology integrate with?
Which of the following methods can the technology integrate with?
What is the approximate cost of producing 1000 tablets of the GMP pullulan mixture?
What is the approximate cost of producing 1000 tablets of the GMP pullulan mixture?
How much does the stabilization mixture add per vaccine?
How much does the stabilization mixture add per vaccine?
What is a significant cost-saving advantage of the proposed system?
What is a significant cost-saving advantage of the proposed system?
What type of patent applications have been filed for the pullulan-based tablets?
What type of patent applications have been filed for the pullulan-based tablets?
What does the Freedom to Operate assessment reveal?
What does the Freedom to Operate assessment reveal?
What is a potential market application for the technology besides vaccines?
What is a potential market application for the technology besides vaccines?
Flashcards
Grant Application Type
Grant Application Type
Application for a grant focused on Strategic Projects, specifically aimed at the transition from an idea to an innovation.
Applicant's Name and Information
Applicant's Name and Information
Details such as family name, given name, initials, personal identification number, and department of the applicant.
Institution Administering the Grant
Institution Administering the Grant
The university or college responsible for overseeing the grant's execution.
Proposed Research Time Commitment
Proposed Research Time Commitment
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Application Title
Application Title
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Proposal Keywords
Proposal Keywords
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Research Subject Code(s)
Research Subject Code(s)
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Grant Application Language
Grant Application Language
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What is a PIN in this context?
What is a PIN in this context?
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What is the purpose of a Co-applicant's organization?
What is the purpose of a Co-applicant's organization?
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What is the significance of the 'general conditions governing grants'?
What is the significance of the 'general conditions governing grants'?
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What is the 'Program Guide for Professors'?
What is the 'Program Guide for Professors'?
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Who is a Collaborator?
Who is a Collaborator?
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What does 'Research/activity time' indicate?
What does 'Research/activity time' indicate?
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What is an 'Organization/Department'?
What is an 'Organization/Department'?
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What is the significance of 'Valid' in the collaborator section?
What is the significance of 'Valid' in the collaborator section?
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What is Advanced Theranostics Inc. focused on?
What is Advanced Theranostics Inc. focused on?
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What is Advanced Theranostics Inc.'s goal with their tests?
What is Advanced Theranostics Inc.'s goal with their tests?
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What is the importance of reagent stabilization?
What is the importance of reagent stabilization?
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How does pullulan help in this research?
How does pullulan help in this research?
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What is the research collaboration focused on?
What is the research collaboration focused on?
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What is the estimated value of in-kind contributions?
What is the estimated value of in-kind contributions?
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What is the research expected to accomplish?
What is the research expected to accomplish?
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What is the overall goal of the collaboration?
What is the overall goal of the collaboration?
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Grant Applicant's Proposed Salary
Grant Applicant's Proposed Salary
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Research Personnel
Research Personnel
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Research Assistant's Experience
Research Assistant's Experience
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Lab Technician's Role
Lab Technician's Role
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Salary and Fringe Benefits
Salary and Fringe Benefits
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Materials and Supplies
Materials and Supplies
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Time Commitment
Time Commitment
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Research Budget Justification
Research Budget Justification
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What is a Discovery Grant?
What is a Discovery Grant?
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What is a SPG grant?
What is a SPG grant?
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What is the focus of the Discovery Grant mentioned?
What is the focus of the Discovery Grant mentioned?
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What is unique about the DNAPrint project?
What is unique about the DNAPrint project?
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What is the budgetary overlap between the SPG proposal and the Discovery Grant?
What is the budgetary overlap between the SPG proposal and the Discovery Grant?
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What is pullulan?
What is pullulan?
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Why is reagent stabilization important?
Why is reagent stabilization important?
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What is the benefit of using pullulan-based tablets?
What is the benefit of using pullulan-based tablets?
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How does pullulan technology benefit diagnostic tests?
How does pullulan technology benefit diagnostic tests?
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What makes pullulan technology valuable for companies?
What makes pullulan technology valuable for companies?
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What is the main cost associated with pullulan tablets?
What is the main cost associated with pullulan tablets?
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What does 'Freedom to Operate' mean in this context?
What does 'Freedom to Operate' mean in this context?
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What is the potential impact of pullulan technology on the market?
What is the potential impact of pullulan technology on the market?
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Study Notes
Application for a Grant
- Applicant: Filipe Carlos
- Grant Type: Idea to Innovation
- Institution: McMaster University
- Department: Chemical Engineering
- Date: 2016/07/04
- PIN: 256630
Proposal Details
- Title: Validation and Scale Up of Vaccine Stabilization for Ambient Handling Using a Pullulan/Trehalose Formulation
- Keywords: vaccine stabilization, in vitro validation, in vivo validation, scale up, optimization, ambient handling
- Total Amount Requested: $125,000
Collaborators
- Jahanshahi Anbuhi: PIN: 501309, McMaster University, 80 hours/month
- Ashkar, A: McMaster University, 30 hours/month
- Co-Applicants' Organizations: GSK Canada - GlaxoSmithKline, Advanced Theranostics Inc.
Activity Schedule
- Optimization of pullulan molecular weights & casting method: 2016-10-03 to 2016-12-30
- Formulation (vaccine trials in vitro): 2016-11-01 to 2017-04-30
- Vaccine Trials (in vivo): 2016-12-01 to 2017-06-30
- Characterization of performance under varying conditions: 2017-03-01 to 2017-06-15
- Scale-up methods for large-scale manufacturing: 2017-04-01 to 2017-06-30
- Develop/source additional partners for licensing technology: 2017-04-01 to 2017-08-31
- Final Report: 2017-08-01 to 2017-10-02
Proposed Expenditures
- Salaries and Benefits: $80,500 (Year 1), $15,000 (Year 1)
- Equipment: $5,000 (Year 1), $0 (Year 2, 3, 4, 5)
- Materials and supplies: $25,000 (Year 1), $2,000 (Year 1), $10,000 (Year 1)
- Technology Transfer Activities: $7,500 (Year 1)
- Total Proposed Expenditures: $125,000
Intellectual Property
- Patent Application: Filed for "Method for Stabilizing Various Molecules without Refrigeration Using Water Soluble Polymers" (US provisional patent application, 61/901,784, 2013-11-08)
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Description
This proposal outlines the validation and scale-up process of a novel vaccine stabilization formulation using a pullulan/trehalose approach. The goal is to facilitate ambient handling and optimize vaccine stability through rigorous in vitro and in vivo trials. Collaborators from McMaster University and other organizations will be involved in this significant project.
