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Questions and Answers
Stereochemistry can affect drug-receptor interaction.
Stereochemistry can affect drug-receptor interaction.
True
Enantiomers always have the same physical and chemical properties.
Enantiomers always have the same physical and chemical properties.
False
Isosteres are groups of atoms possessing different physical and chemical properties.
Isosteres are groups of atoms possessing different physical and chemical properties.
False
Dipole interactions play a crucial role in drug-receptor interactions.
Dipole interactions play a crucial role in drug-receptor interactions.
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Ion-dipole interactions are irrelevant in drug-receptor interactions.
Ion-dipole interactions are irrelevant in drug-receptor interactions.
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Conjugation reactions result in products with lower molecular weight compared to their substrates.
Conjugation reactions result in products with lower molecular weight compared to their substrates.
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Phase I reactions generally produce more active metabolites compared to conjugation reactions.
Phase I reactions generally produce more active metabolites compared to conjugation reactions.
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The addition of large cationic groups like GSH detoxifies reactive electrophiles.
The addition of large cationic groups like GSH detoxifies reactive electrophiles.
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Glutathione S-transferases belong to the group of broad-specificity transferases.
Glutathione S-transferases belong to the group of broad-specificity transferases.
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Glucuronidation is catalyzed by UDP-glucuronosyltransferases.
Glucuronidation is catalyzed by UDP-glucuronosyltransferases.
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