Chapter 6: Enzyme Kinetics Study Quiz
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Questions and Answers

Which type of inhibitor binds to an enzyme at a location other than the active site?

  • Competitive inhibitor
  • Noncompetitive inhibitor (correct)
  • Reversible covalent modification
  • Allosteric inhibitor

    • What is the primary effect of a competitive inhibitor on Vmax in enzyme kinetics?

  • Increase Vmax
  • Reverse Vmax
  • Decrease Vmax (correct)
  • No effect on Vmax

    • How does a noncompetitive inhibitor affect the Km value in enzyme kinetics?

  • Increase Km
  • Decrease Km
  • No effect on Km (correct)
  • Reverse Km

    • In terms of Lineweaver-Burk plot, how would a competitive inhibitor affect the slope of the line?

    <p>Increase the slope</p> Signup and view all the answers

    Which type of inhibition involves a molecule that resembles the substrate and competes for the enzyme's active site?

    <p>Competitive inhibition</p> Signup and view all the answers

    What is a characteristic feature of noncompetitive inhibitors regarding their interaction with enzymes?

    <p>They alter the enzyme's shape</p> Signup and view all the answers

    What type of molecules are cofactors in enzyme kinetics?

    <p>Small non-protein molecules</p> Signup and view all the answers

    Which of the following is NOT a cofactor mentioned in the text?

    <p>Acetyl CoA carboxylase</p> Signup and view all the answers

    Where do zymogens play a role in enzyme kinetics?

    <p>Activating enzyme activity</p> Signup and view all the answers

    What is the role of metal cofactors in enzyme kinetics?

    <p>Aid in enzyme activity</p> Signup and view all the answers

    Which enzyme regulation mechanism involves noncompetitive inhibitors?

    <p>Allosteric regulation</p> Signup and view all the answers

    In the Lineweaver-Burk plot, what effect does a competitive inhibitor have on the slope of the lines?

    <p>No effect on the slope</p> Signup and view all the answers

    What type of inhibitors compete with the substrate for the active site of the enzyme?

    <p>Competitive inhibitors</p> Signup and view all the answers

    How do noncompetitive inhibitors affect Vmax and Km?

    <p>Decrease Vmax, no effect on Km</p> Signup and view all the answers

    What effect do competitive inhibitors have on a Lineweaver-Burk plot?

    <p>Lines intersect at a new point on the y-axis</p> Signup and view all the answers

    Which type of inhibitor binds to an allosteric site on the enzyme rather than the active site?

    <p>Noncompetitive inhibitors</p> Signup and view all the answers

    What is the effect of noncompetitive inhibitors on enzyme activity?

    <p>Decrease enzyme activity</p> Signup and view all the answers

    What is the role of a prosthetic group in enzyme kinetics?

    <p>Facilitate catalytic activity as a tightly bound cofactor</p> Signup and view all the answers

    Which enzyme regulation mechanism involves the use of metal cofactors?

    <p>Allosteric regulation</p> Signup and view all the answers

    What is the primary function of deoxyadenosyl cobalamin in enzyme kinetics?

    <p>Facilitating methylmalonyl mutase activity</p> Signup and view all the answers

    In enzyme kinetics, what is the main function of coenzyme A (CoA)?

    <p>Participating in acetyl group transfer reactions</p> Signup and view all the answers

    How do metal cofactors contribute to enzyme kinetics?

    <p>Enhance catalytic activity by stabilizing enzyme-substrate complexes</p> Signup and view all the answers

    What is the primary function of the digestive enzymes synthesized as zymogens in the stomach and pancreas?

    <p>Protein digestion</p> Signup and view all the answers

    Which enzyme is responsible for converting pepsinogens to pepsins in the gastric lumen?

    <p>Pepsin</p> Signup and view all the answers

    Which enzyme is NOT involved in the coagulation cascade for blood clotting?

    <p>Chymotrypsin</p> Signup and view all the answers

    What is the role of procarboxypeptidases A and B in the pancreatic digestion process?

    <p>Hydrolysis of proteins</p> Signup and view all the answers

    Which enzyme participates in the breakdown of triglycerides into free fatty acids during pancreatic digestion?

    <p>Pancreatic lipase</p> Signup and view all the answers

    Which type of enzyme catalyzes the transfer of functional groups between different molecules?

    <p>Transferase</p> Signup and view all the answers

    What is the function of Isomerases among the mentioned enzyme classifications?

    <p>Facilitate isomerization reactions within molecules</p> Signup and view all the answers

    Which of the following enzymes is involved in joining two molecules together?

    <p>Ligase</p> Signup and view all the answers

    Among the mentioned enzyme types, which one is primarily involved in catalyzing oxidation-reduction reactions?

    <p>Oxidoreductase</p> Signup and view all the answers

    What is the main function of Hydrolases in biochemical reactions?

    <p>Catalyze removal of functional groups through hydrolysis reactions</p> Signup and view all the answers

    What is the primary function of ligases in enzyme regulation mechanisms?

    <p>Catalyze the transfer of functional groups from one molecule to another</p> Signup and view all the answers

    Which type of enzyme regulation involves irreversible activation of zymogens/proenzymes?

    <p>Hydrolases</p> Signup and view all the answers

    How do isomerases contribute to enzyme regulation mechanisms?

    <p>Facilitate the conversion of substrates into their isomeric forms</p> Signup and view all the answers

    In enzyme regulation, which group of enzymes undergo irreversible activation cascades?

    <p>Oxidoreductases</p> Signup and view all the answers

    How do transferases contribute to regulating enzyme activity?

    <p>Catalyze the transfer of functional groups between molecules</p> Signup and view all the answers

    Which type of enzymes are caspases, involved in programmed cell death?

    <p>Hydrolases</p> Signup and view all the answers

    In apoptosis, caspases function to cause cell death by degrading proteins indiscriminately. What other enzymes share this indiscriminate degradation characteristic?

    <p>Ligases</p> Signup and view all the answers

    What type of enzyme is procollagenase converted into during the metamorphosis of tadpoles into frogs?

    <p>Ligase</p> Signup and view all the answers

    Which pathway can initiate apoptosis through the activation of caspases?

    <p>Intrinsic pathway</p> Signup and view all the answers

    During apoptosis, what happens to the apoptotic bodies that are produced?

    <p>They are cleared by macrophages</p> Signup and view all the answers

    What is the primary function of homotropic allosteric effectors on enzymes?

    <p>Enhance the catalytic properties of other substrate-binding sites</p> Signup and view all the answers

    In covalent modification of enzymes, what is the primary role of kinases?

    <p>Catalyze the addition of phosphate groups to specific amino acids</p> Signup and view all the answers

    Which term best describes an effector that is different from the substrate and influences enzyme activity?

    <p>Heterotropic effector</p> Signup and view all the answers

    What is a classical example of heterotropic effectors in enzyme regulation?

    <p>Feedback inhibition in a metabolic pathway</p> Signup and view all the answers

    How do positive homotropic effectors influence enzyme activity?

    <p>Enhance the catalytic properties at other sites</p> Signup and view all the answers

    Which type of enzyme catalyzes the transfer of functional groups between molecules?

    <p>Transferases</p> Signup and view all the answers

    What is the primary function of Ligases in cellular physiology?

    <p>Joining molecules together</p> Signup and view all the answers

    Where do zymogens play a significant role in enzyme activation?

    <p>Golgi apparatus</p> Signup and view all the answers

    What characteristic distinguishes Isomerases among other enzyme classes?

    <p>Catalyzing the interconversion of isomers</p> Signup and view all the answers

    In what condition can accidental activation of zymogens prevent enzyme activity?

    <p>Blocked secretion duct in the pancreas</p> Signup and view all the answers

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