Chapter 25: General Anesthetics

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18 Questions

What is a characteristic of inhalational agents' dose-response curves?

Steep curves and narrow therapeutic indices

How can depth of anesthesia be rapidly altered with inhaled gases?

By altering the inhaled concentration

How do IV anesthetics cause rapid induction?

By traveling from arm to brain quickly

What is the mechanism of recovery from IV anesthetics?

Redistribution within the CNS

What is the role of IV anesthetics during longer procedures?

To maintain anesthesia with inhaled agents

In lower doses, IV anesthetics may be used for:

Sedation

Which neurotransmitter is primarily affected by inhaled anesthetics, barbiturates, benzodiazepines, etomidate, and propofol?

GABA

How do inhaled anesthetics primarily diminish CNS activity?

By hyperpolarizing neurons

Which receptors are primarily affected by nitrous oxide and ketamine?

NMDA receptors

What is the key difference between volatile and gaseous anesthetics in terms of physical state?

Gaseous anesthetics are in gas form at room temperature.

What effect do inhalation anesthetics have on glycine receptors in spinal motor neurons?

Increase activity

Which type of general anesthetic does not act on GABAA receptors?

Nitrous oxide

What are the five primary effects characterized by the neurophysiologic state produced by general anesthetics?

Unconsciousness, amnesia, analgesia, inhibition of autonomic reflexes, muscle relaxation

Which route is commonly used to administer general anesthetics?

Orally

What is the main goal of an ideal anesthetic drug?

Induce rapid loss of consciousness and be reversible upon discontinuation

What are the three stages of general anesthesia?

Induction, maintenance, recovery

Which type of anesthesia involves unconsciousness, analgesia, amnesia, skeletal muscle relaxation, and loss of reflexes?

General anesthesia

Why is it challenging for a single anesthetic agent to achieve all five desired effects of general anesthesia well?

Anesthetic agents have limitations in targeting specific receptors

Test your knowledge on the definition and types of general anesthetics. Explore terms like analgesia and general anesthesia, as well as the various methods of administering anesthetics. This quiz is prepared by Racel Trangia-Bactol, a professional in pharmacy and healthcare.

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