l23 MCQ - Cerebrospinal Fluid Quiz

Cerebrospinal Fluid (CSF) Functions

• CSF does not have a function of storing nutrients or waste products.

Brain and CSF Weight

• The brain weighs approximately 1400-1500 grams when floating in CSF.

Intracranial Pressure (ICP)

• Factors that can significantly raise ICP include brain tumors, cerebral edema, and meningitis.

CSF Pressure and ICP

• The normal range of CSF pressure as a guide of ICP is 7-15 mmHg.

CSF Appearance and Protein Levels

• A cloudy appearance of CSF can indicate the presence of white blood cells or bacteria.
• A potential cause of high CSF protein levels is multiple sclerosis.

CSF Glucose Levels

• The normal range for CSF glucose levels is 2.5-4.5 mmol/L.

Circumventricular Organs

• The purpose of circumventricular organs in the brain is to monitor the chemical composition of the blood and CSF.
• These organs regulate the composition of extracellular fluid in the central nervous system (CNS).

CSF Reabsorption and Production

• CSF is reabsorbed into veins through the arachnoid villi.
• The rate of production of CSF is approximately 500-600 mL/day.
• The turnover rate of CSF is approximately 3-4 times per day.

Capillary Membrane and Astrocytes

• The movement of substances across the capillary membrane into the brain is directly proportional to lipid solubility and inversely proportional to size.
• Tight junctions between endothelial cells of capillaries and the endfeet of astrocytes are induced by the blood-brain barrier.

CSF Location and Movement

• The main body fluid compartment where the majority of CSF is located is the subarachnoid space.
• The movement of CSF in the ventricles and subarachnoid space is caused by the pulsatile flow of cerebral arteries.

Test your knowledge on cerebrospinal fluid and its role in the body. This quiz covers topics such as transcellular fluid, the blood-brain barrier, and movement of substances into the brain. Recommended reading: Neuroscience 6/e by Purves et al.