l23 MCQ - Cerebrospinal Fluid Quiz

Cerebrospinal Fluid (CSF) Functions

• CSF does not have a function of storing nutrients or waste products.

Brain and CSF Weight

• The brain weighs approximately 1400-1500 grams when floating in CSF.

Intracranial Pressure (ICP)

• Factors that can significantly raise ICP include brain tumors, cerebral edema, and meningitis.

CSF Pressure and ICP

• The normal range of CSF pressure as a guide of ICP is 7-15 mmHg.

CSF Appearance and Protein Levels

• A cloudy appearance of CSF can indicate the presence of white blood cells or bacteria.
• A potential cause of high CSF protein levels is multiple sclerosis.

CSF Glucose Levels

• The normal range for CSF glucose levels is 2.5-4.5 mmol/L.

Circumventricular Organs

• The purpose of circumventricular organs in the brain is to monitor the chemical composition of the blood and CSF.
• These organs regulate the composition of extracellular fluid in the central nervous system (CNS).

CSF Reabsorption and Production

• CSF is reabsorbed into veins through the arachnoid villi.
• The rate of production of CSF is approximately 500-600 mL/day.
• The turnover rate of CSF is approximately 3-4 times per day.

Capillary Membrane and Astrocytes

• The movement of substances across the capillary membrane into the brain is directly proportional to lipid solubility and inversely proportional to size.
• Tight junctions between endothelial cells of capillaries and the endfeet of astrocytes are induced by the blood-brain barrier.

CSF Location and Movement

• The main body fluid compartment where the majority of CSF is located is the subarachnoid space.
• The movement of CSF in the ventricles and subarachnoid space is caused by the pulsatile flow of cerebral arteries.