Podcast
Questions and Answers
Which pathway carries input from leg proprioceptors to the cerebellum?
Which pathway carries input from leg proprioceptors to the cerebellum?
Which nucleus projects to the dentate nucleus in the cerebellum?
Which nucleus projects to the dentate nucleus in the cerebellum?
Which cerebellar peduncle carries input from the vestibular system to the cerebellum?
Which cerebellar peduncle carries input from the vestibular system to the cerebellum?
Which structure carries input from arm proprioceptors to the cerebellum?
Which structure carries input from arm proprioceptors to the cerebellum?
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Which nuclei are located in the intermediate hemisphere of the cerebellum?
Which nuclei are located in the intermediate hemisphere of the cerebellum?
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Which region of the cerebellum is primarily responsible for balance and the vestibulo-ocular reflex (VOR)?
Which region of the cerebellum is primarily responsible for balance and the vestibulo-ocular reflex (VOR)?
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Which cortical area is the primary source of input to the caudate and putamen in the basal ganglia?
Which cortical area is the primary source of input to the caudate and putamen in the basal ganglia?
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Which region of the cerebellum is involved in motor planning for the extremities?
Which region of the cerebellum is involved in motor planning for the extremities?
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Which cortical area is the primary target of outputs from the globus pallidus internal segment (GPI) and substantia nigra pars reticulata (SNr)?
Which cortical area is the primary target of outputs from the globus pallidus internal segment (GPI) and substantia nigra pars reticulata (SNr)?
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Which region of the cerebellum is involved in distal limb coordination?
Which region of the cerebellum is involved in distal limb coordination?
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Which cortical area is involved in the oculomotor pathway for eye movement?
Which cortical area is involved in the oculomotor pathway for eye movement?
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Study Notes
Cerebellar Inputs
- Main input pathways to the cerebellum include:
- Pontocerebellar fibers from the cortex
- Spinocerebellar pathways from leg proprioceptors via the dorsal spinocerebellar tract and nucleus dorsalis of Clark
- Arm proprioceptors via the cuneocerebellar tract and external cuneate nucleus
- Vestibular inputs from the vestibular system, vestibular ganglia, and vestibular nuclei
Cerebellar Outputs
- Main output targets of the cerebellum include:
- Dentate nucleus in the lateral hemisphere, projecting to the ventrolateral nucleus of the thalamus (VL) and connected to premotor cortex, SMA, motor cortex, and parietal cortex
- Interposed nuclei in the intermediate hemisphere, projecting to VL and connected to premotor cortex, SMA, and motor cortex
- Fastigial nucleus in the vermis, projecting to VL and connected to motor cortex, and motor association areas
- Vestibular nuclei and fastigial nuclei in the inferior vermis and flocculonodular lobe, projecting to the juxtarestiform body and MLF (eye movement pathways)
Functions of Cerebellar Pathways
- Lateral hemispheres:
- Involved in motor planning for extremities
- Influence ipsilateral and bilateral motor pathways
- Intermediate hemisphere:
- Involved in distal limb coordination
- Influences LCST and rubrospinal pathways
- Vermis and flocculonodular lobe:
- Involved in balance and VOR
- Influence MLF channels
Basal Ganglia Input Nuclei
- Receive cortical input from:
- Somatosensory cortex, primary motor cortex, and premotor cortex
- Project to thalamic relay nuclei, including:
- Putamen and GPI (motor regions)
- Caudate (oculomotor, pre-frontal, and limbic regions)
Channels of Basal Ganglia
- Motor channel: connected to primary motor cortex, premotor cortex, and supplementary motor area
- Oculomotor channel: connected to frontal eye fields and supplementary eye fields
- Prefrontal channel: connected to prefrontal cortex
- Limbic channel: connected to anterior cingulate and orbital frontal cortex
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Description
Test your knowledge on the input pathways to the cerebellum including origins of input cells, pontocerebellar fibers, spinocerebellar pathways, and vestibular inputs.
