Cephalosporins Overview Quiz

Which of the following cephalosphorins is primarily effective against Gram+ microorganisms?

What is a characteristic of second generation cephalosphorins?

Which of the following cephalosphorins is primarily indicated for treating Pseudomonas aeruginosa infections?

Which class of cephalosphorins has the broadest spectrum of activity?

Which of the following is true regarding the activity of third generation cephalosphorins?

Which of the following agents is a first generation cephalosphorin?

Which type of infections are cephalosphorins commonly used to manage?

Which of the following characteristics distinguishes first generation cephalosphorins from others?

Cephalosporins

Cephalosporins are a class of antibiotics that work by inhibiting bacterial cell wall synthesis.
Different generations of cephalosporins have varying effectiveness against different types of bacteria.

First Generation Cephalosporins

Primarily effective against Gram-positive bacteria like Staphylococcus and Streptococcus.
Show limited activity against Gram-negative bacteria.
Examples include cefadroxil, cefazolin, cephalexin, cephalotin, cephradine, and cephapirin.

Second Generation Cephalosporins

Exhibit greater activity against Gram-negative bacteria, including Escherichia, Kleibsiella, and Proteus.
More effective than first-generation cephalosporins against these bacteria types.
Examples include cefaclor, cefamandole, cefmetazole, cefonicid, cefoxitin, cefprozil, loracarbef, and cefuroxime.

Third Generation Cephalosporins

Generally less effective against Gram-positive bacteria compared to first-generation cephalosporins.
Highly effective against penicillinase-producing bacteria, particularly Pseudomonas aeruginosa.
Examples include cefdinir, cefixime, cefoperazone, cefotaxime, cefotetan, cefpodoxime, ceftazidime, ceftibuten, ceftizoxime, and ceftriaxone.

Fourth Generation Cephalosporins

Broad-spectrum antibiotics, active against both Gram-positive and Gram-negative bacteria.
Example: cefepime.

Clinical Applications

Used in various infections, including urinary tract infections, respiratory tract infections, abdominal infections, septicemia, meningitis, and osteomyelitis.

Test your knowledge on cephalosporins, a class of antibiotics that inhibit bacterial cell wall synthesis. This quiz covers the various generations of cephalosporins, their effectiveness against different bacteria, and notable examples from each generation.