Questions and Answers
What generation of cephalosporin is Cephazolin?
What generation of cephalosporin is Cephalexin?
What generation of cephalosporin is Cefadroxil?
What generation of cephalosporin is Cefoxitin?
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What generation of cephalosporin is Cefaclor?
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What generation of cephalosporin is Cefprozil?
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What generation of cephalosporin is Cefuroxime?
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What generation of cephalosporin is Cefotetan?
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What generation of cephalosporin is Cefamandole?
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What generation of cephalosporin is Ceftriaxone?
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What generation of cephalosporin is Cefotaxime?
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What generation of cephalosporin is Cefpodoxime?
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What generation of cephalosporin is Ceftibuten?
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What generation of cephalosporin is Cefdinir?
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What generation of cephalosporin is Ceftizoxime?
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What generation of cephalosporin is Ceftazidime?
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What generation of cephalosporin is Cefepime?
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What generation of cephalosporin is Ceftaroline?
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Study Notes
Cephalosporin Classes Overview
- Cephalosporins are classified into generations based on their spectrum of activity and chemical structure.
- Each generation has different effectiveness against bacteria and is used for various infections.
1st Generation Cephalosporins
- Primarily effective against Gram-positive bacteria and some Gram-negative bacteria.
- Common agents include:
- Cephazolin: Often used for surgical prophylaxis.
- Cephalexin: Administered for skin infections and respiratory tract infections.
- Cefadroxil: Similar uses to Cephalexin, available in a once-daily dosing form.
2nd Generation Cephalosporins
- Broader spectrum against Gram-negative bacteria compared to the first generation.
- Key agents include:
- Cefoxitin: Effective against anaerobes; commonly used in intra-abdominal infections.
- Cefaclor: Used for respiratory tract and urinary tract infections.
- Cefprozil: Used for skin and respiratory infections, effective against certain resistant strains.
- Cefuroxime: Used for respiratory, ear, and skin infections; has oral and injectable forms.
- Cefotetan: Noted for effectiveness against anaerobic bacteria.
- Cefamandole: Can be used in serious infections, though less commonly prescribed now.
3rd Generation Cephalosporins
- Increased Gram-negative coverage, including some strains resistant to earlier generations.
- Main agents include:
- Ceftriaxone: Broad-spectrum; often used in severe infections such as meningitis.
- Cefotaxime: Commonly utilized for various infections, including sepsis.
- Cefpodoxime: Available orally, used for respiratory and urinary tract infections.
- Ceftibuten: Effective for respiratory infections, convenient oral form.
- Cefdinir: Used for skin infections and otitis media in children.
- Ceftizoxime: Has a broad-spectrum coverage; effective against resistant strains.
- Ceftazidime: Notable for activity against Pseudomonas aeruginosa.
4th Generation Cephalosporins
- Extended spectrum, with effectiveness against both Gram-negative and Gram-positive bacteria, as well as resistant strains.
- Cefepime: Used in serious infections and for hospital-acquired pathogens; provides broad-spectrum coverage.
5th Generation Cephalosporins
- Designed to combat resistant Gram-positive bacteria, including MRSA.
- Ceftaroline: The only cephalosporin effective against MRSA; used in skin infections and community-acquired pneumonia.
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Description
This quiz offers an overview of cephalosporin classes, detailing the characteristics and uses of different generations. It covers the effectiveness of first and second-generation cephalosporins against various types of bacteria. Test your knowledge about these important antibiotics and their applications.