Central Nervous System Overview
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Questions and Answers

Which part of the brain is connected to the dorsal aspect of the brainstem?

  • Parietal lobe
  • Frontal lobe
  • Cerebrum
  • Cerebellum (correct)
  • What structure protects the Central Nervous System?

  • Grey matter
  • White matter
  • Cerebro Spinal Fluid
  • Meninges (correct)
  • Which of the following is NOT a lobe of the cerebrum?

  • Occipital lobe
  • Temporal lobe
  • Cerebellar lobe (correct)
  • Frontal lobe
  • Which component is NOT involved in the composition of the Central Nervous System?

    <p>Peripheral nerves</p> Signup and view all the answers

    How is the nervous tissue organized in the Central Nervous System?

    <p>In white and grey matter</p> Signup and view all the answers

    Which of the following is a function of the corpus callosum?

    <p>Connects the left and right cerebral hemispheres</p> Signup and view all the answers

    Which part of the brainstem is responsible for regulating vital functions such as heart rate and respiration?

    <p>Medulla oblongata</p> Signup and view all the answers

    What is the primary function of the thalamus in the diencephalon?

    <p>Relays sensory information to the cerebral cortex</p> Signup and view all the answers

    Which of the following structures is part of the midbrain?

    <p>Crus cerebri</p> Signup and view all the answers

    Where does the spinal cord typically end in adults?

    <p>L1-L2 vertebral level</p> Signup and view all the answers

    Which part of the brain is involved in the control of voluntary motor movements and procedural learning?

    <p>Basal ganglia</p> Signup and view all the answers

    Which of the following structures in the brainstem is responsible for controlling the auditory and visual reflexes?

    <p>Quadrigeminal plate</p> Signup and view all the answers

    The spinal cord contains 31 pairs of spinal nerves. Which of the following is NOT a part of these nerves?

    <p>Pelvic nerves</p> Signup and view all the answers

    Which of the following statements about the cerebrum is correct?

    <p>It is divided into two hemispheres that are connected by the corpus callosum.</p> Signup and view all the answers

    The spinal cord typically ends at which vertebral level in adults?

    <p>L1-L2</p> Signup and view all the answers

    Which of the following spinal nerves is primarily involved in the motor innervation of the diaphragm?

    <p>C4</p> Signup and view all the answers

    The spinal cord ends at the L1-L2 level, but the spinal nerves continue in a structure called:

    <p>Cauda equina</p> Signup and view all the answers

    At what stage does the notochord induce the differentiation of the ectoderm into neuroectoderm?

    <p>Day 17</p> Signup and view all the answers

    During neural tube development, the process of 'zipping' begins around which day?

    <p>Day 22</p> Signup and view all the answers

    Which of the following is the result of failure of the anterior neuropore to close?

    <p>Anencephaly</p> Signup and view all the answers

    Which of the following developmental structures forms from the neural crest cells?

    <p>Pigment-producing cells of the epidermis</p> Signup and view all the answers

    The zipping of the neural tube completes at the cranial end around which day?

    <p>Day 26</p> Signup and view all the answers

    The closure of the posterior neuropore (caudal end) of the neural tube occurs by which day?

    <p>Day 27</p> Signup and view all the answers

    Which of the following disorders is associated with the failure of the posterior neuropore to close?

    <p>Spina bifida</p> Signup and view all the answers

    Which vitamin deficiency is associated with improper closure of the neural tube?

    <p>Vitamin B9 (Folate)</p> Signup and view all the answers

    Which of the following cells is NOT derived from the neural crest?

    <p>Cerebral cortex neurons</p> Signup and view all the answers

    Which region of the neural tube will develop into the spinal cord?

    <p>Caudal end (spinal cord)</p> Signup and view all the answers

    Which of the following best describes the process of neurulation?

    <p>The formation of the neural tube from the ectoderm</p> Signup and view all the answers

    At what stage does the neural plate form?

    <p>Day 17</p> Signup and view all the answers

    What is the outcome of the failure of the posterior neuropore to close during neural tube formation?

    <p>Spina bifida</p> Signup and view all the answers

    Which of the following is true about the neural crest cells?

    <p>They contribute to the formation of peripheral neurons, glial cells, and pigment-producing cells.</p> Signup and view all the answers

    The failure of the anterior neuropore to close results in which condition?

    <p>Anencephaly</p> Signup and view all the answers

    What is the primary function of the notochord during early neural development?

    <p>It induces the differentiation of the ectoderm into neuroectoderm.</p> Signup and view all the answers

    At which day does the closure of the anterior (cranial) neuropore occur?

    <p>Day 26</p> Signup and view all the answers

    Which of the following is NOT a function of the neural crest cells?

    <p>Formation of glial cells in the central nervous system</p> Signup and view all the answers

    Neural tube formation leads to the development of which of the following structures?

    <p>Spinal cord and brain</p> Signup and view all the answers

    Which structure gives rise to the brain and spinal cord in vertebrate development?

    <p>Neural plate</p> Signup and view all the answers

    Which of the following conditions is directly associated with the failure of folate (Vitamin B9) during early neural development?

    <p>Both A and B</p> Signup and view all the answers

    Which part of the neural tube develops into the spinal cord?

    <p>Caudal portion</p> Signup and view all the answers

    What role do the neural folds play in the formation of the neural tube?

    <p>They eventually fuse to form the neural tube.</p> Signup and view all the answers

    Failure of closure of the anterior neuropore results in which developmental defect?

    <p>Anencephaly</p> Signup and view all the answers

    The cranial part of the neural tube enlarges to form which of the following?

    <p>Cerebral vesicles</p> Signup and view all the answers

    At approximately what day of development do the primary vesicles of the neural tube form?

    <p>Day 20</p> Signup and view all the answers

    The cerebrum, thalamus, and hypothalamus are derivatives of which secondary vesicle?

    <p>Forebrain (prosencephalon)</p> Signup and view all the answers

    Which of the following structures is a derivative of the metencephalon?

    <p>Cerebellum</p> Signup and view all the answers

    Which of the following is the primary function of cerebrospinal fluid (CSF)? A) To provide nutrients to the neurons B) To cushion and protect the brain and spinal cord C) To transmit electrical impulses D) To provide structural support to the spinal cord

    <p>To cushion and protect the brain and spinal cord</p> Signup and view all the answers

    Which of the following spaces exists between the dura mater and arachnoid mater?

    <p>Subdural space</p> Signup and view all the answers

    The epidural space does not normally exist around which of the following?

    <p>Brain</p> Signup and view all the answers

    The space between the arachnoid mater and the pia mater is called the:

    <p>Subarachnoid space</p> Signup and view all the answers

    Which of the following structures is a derivative of the myelencephalon?

    <p>Medulla</p> Signup and view all the answers

    Which of the following spaces does not normally exist around the spinal cord?

    <p>Subdural space</p> Signup and view all the answers

    Which meninges layer is directly adhered to the surface of the brain and spinal cord?

    <p>Pia mater</p> Signup and view all the answers

    The thalamus and hypothalamus are derivatives of which secondary vesicle?

    <p>Diencephalon</p> Signup and view all the answers

    At what stage of development do secondary vesicles form from the primary vesicles?

    <p>Day 32</p> Signup and view all the answers

    Which of the following is true about the subarachnoid space?

    <p>It is filled with cerebrospinal fluid (CSF) and cushions the brain.</p> Signup and view all the answers

    Which of the following is derived from the prosencephalon (forebrain)?

    <p>Cerebrum and thalamus</p> Signup and view all the answers

    Where is cerebrospinal fluid (CSF) primarily produced?

    <p>Choroid plexus in the lateral and III ventricles</p> Signup and view all the answers

    Which of the following structures does NOT significantly contribute to the production of cerebrospinal fluid (CSF)?

    <p>Fourth ventricle</p> Signup and view all the answers

    From the lateral ventricles, cerebrospinal fluid (CSF) flows through which structure to reach the third ventricle?

    <p>Interventricular foramen (Monro)</p> Signup and view all the answers

    After passing through the cerebral aqueduct, where does the cerebrospinal fluid (CSF) flow next?

    <p>Both A and B</p> Signup and view all the answers

    Which of the following is the primary function of the lateral and median apertures in the fourth ventricle?

    <p>To drain CSF into the subarachnoid space</p> Signup and view all the answers

    Cerebrospinal fluid (CSF) is reabsorbed into the bloodstream primarily through which structure?

    <p>Subarachnoid space and arachnoid villi</p> Signup and view all the answers

    Which of the following statements about the CSF circulation is true?

    <p>The CSF flows from the lateral ventricles to the third ventricle and then to the fourth ventricle before entering the subarachnoid space.</p> Signup and view all the answers

    Which of the following structures connects the third ventricle to the fourth ventricle in the CSF circulation system?

    <p>Cerebral aqueduct (Sylvius)</p> Signup and view all the answers

    How much cerebrospinal fluid (CSF) typically enters the central canal of the spinal cord?

    <p>A minimal quantity</p> Signup and view all the answers

    Where is cerebrospinal fluid (CSF) primarily reabsorbed back into the bloodstream?

    <p>Through the arachnoid villi in the subarachnoid space</p> Signup and view all the answers

    Which structure is responsible for producing the majority of cerebrospinal fluid (CSF)?

    <p>Choroid plexus in the lateral and third ventricles</p> Signup and view all the answers

    What is the primary function of the subarachnoid space?

    <p>To act as a protective water cushion for the brain and spinal cord</p> Signup and view all the answers

    Which of the following is true about the subarachnoid space around the brain? (Select one)

    <p>The subarachnoid space around the brain is irregular and forms cisterns at certain locations.</p> Signup and view all the answers

    How does the subarachnoid space around the spinal cord differ from that around the brain?

    <p>It is more regular in width.</p> Signup and view all the answers

    The subarachnoid space is directly continuous with which of the following?

    <p>The fourth ventricle</p> Signup and view all the answers

    Which of the following structures is found in the subarachnoid space and helps in the circulation of cerebrospinal fluid (CSF)?

    <p>Arachnoid villi</p> Signup and view all the answers

    Which of the following is a characteristic of the subarachnoid space around the brain?

    <p>It is irregular, with enlarged areas forming cisterns.</p> Signup and view all the answers

    What distinguishes the subarachnoid space around the brain from the spinal cord?

    <p>The width is more irregular around the brain, forming cisterns</p> Signup and view all the answers

    Which of the following locations does cerebrospinal fluid (CSF) flow into from the fourth ventricle?

    <p>Subarachnoid space</p> Signup and view all the answers

    Which of the following structures is associated with the protective function of the subarachnoid space?

    <p>Cerebrospinal fluid (CSF)</p> Signup and view all the answers

    Where does the subarachnoid space around the brain form cisterns?

    <p>At the points where the subarachnoid space widens</p> Signup and view all the answers

    Which of the following is a primary component of the central nervous system (CNS)?

    <p>All of the above</p> Signup and view all the answers

    What type of glial cells are found in the central nervous system (CNS)?

    <p>Oligodendrocytes</p> Signup and view all the answers

    Which of the following is analogous to astrocytes in the peripheral nervous system (PNS)?

    <p>Satellite cells</p> Signup and view all the answers

    What structure in the CNS corresponds to nerve fibers in the PNS?

    <p>Tracts</p> Signup and view all the answers

    In the peripheral nervous system (PNS), what is a bundle of nerve fibers called?

    <p>Nerve</p> Signup and view all the answers

    Where are the cell bodies of neurons located in the central nervous system (CNS)?

    <p>In the grey matter</p> Signup and view all the answers

    Which of the following best describes the function of glial cells in the nervous system?

    <p>Providing structural and metabolic support for neurons</p> Signup and view all the answers

    Which of the following is true about the organization of nerve fibers in the CNS?

    <p>Nerve fibers are grouped into tracts in the CNS.</p> Signup and view all the answers

    Which cells in the CNS are primarily responsible for the formation of myelin?

    <p>Oligodendrocytes</p> Signup and view all the answers

    What type of connective tissue support is provided for neurons in the CNS?

    <p>Meninges</p> Signup and view all the answers

    What is the role of Schwann cells in the peripheral nervous system (PNS)?

    <p>To form myelin sheaths around axons</p> Signup and view all the answers

    What is the primary role of oligodendrocytes in the central nervous system?

    <p>Supporting the formation of myelin sheaths</p> Signup and view all the answers

    Which type of fibers connect different parts of the same hemisphere of the brain?

    <p>Association fibers</p> Signup and view all the answers

    Which of the following statements best describes the blood-brain barrier?

    <p>It strictly regulates permeability of brain capillaries.</p> Signup and view all the answers

    What is the significance of the nodes of Ranvier in myelinated axons?

    <p>They facilitate saltatory conduction.</p> Signup and view all the answers

    What is the composition of grey matter primarily made up of?

    <p>Unmyelinated axons and cell bodies</p> Signup and view all the answers

    In what condition can the blood-brain barrier become temporarily permeable?

    <p>In conditions like meningitis</p> Signup and view all the answers

    What structural feature is characteristic of oligodendrocytes?

    <p>They wrap around axons to form myelin sheaths.</p> Signup and view all the answers

    What is an implication of the breakdown of the blood-brain barrier?

    <p>Implicated in pathophysiology of diseases such as MS</p> Signup and view all the answers

    What is the primary function of astrocytes in the central nervous system (CNS)?

    <p>Supporting neurons and forming scars after injury</p> Signup and view all the answers

    Which glial cell type is responsible for forming myelin sheaths in the CNS?

    <p>Oligodendrocytes</p> Signup and view all the answers

    What is the role of microglia in the CNS?

    <p>Regulating the immune response</p> Signup and view all the answers

    Which of the following is a characteristic feature of white matter in the CNS?

    <p>Contains myelinated axons</p> Signup and view all the answers

    Which type of nerve fibers are responsible for communication between different parts of the same hemisphere of the brain?

    <p>Association fibers</p> Signup and view all the answers

    What is the purpose of the blood-brain barrier?

    <p>To prevent harmful substances in the blood from entering the brain</p> Signup and view all the answers

    What type of fibers are responsible for transmitting signals from the periphery to the center of the nervous system?

    <p>Afferent fibres</p> Signup and view all the answers

    Which of the following correctly describes the composition of peripheral nerves?

    <p>They are composed of nerve fibres grouped in parallel and wrapped in connective tissue.</p> Signup and view all the answers

    What is the role of ganglia in the peripheral nervous system?

    <p>To group the cell bodies of nerve fibres.</p> Signup and view all the answers

    What is the function of the myelin sheath in peripheral nerves?

    <p>To insulate the nerve fibres and speed up signal transmission.</p> Signup and view all the answers

    What are nerve plexi?

    <p>Networks of interconnected nerve fibres.</p> Signup and view all the answers

    Which of the following statements about nerve fibres in peripheral nerves is true?

    <p>Nerve fibres are parallel with each other and wrapped by connective tissue.</p> Signup and view all the answers

    What is the connective tissue that surrounds individual nerve fibres in the peripheral nervous system called?

    <p>Endoneurium</p> Signup and view all the answers

    What denotes the vascularization within peripheral nerves?

    <p>Blood vessels that run parallel to the nerve fibres.</p> Signup and view all the answers

    What type of nerve fibres can be found in a peripheral nerve?

    <p>Motor, sensory, and autonomic nerve fibres</p> Signup and view all the answers

    What is the primary role of neurotransmitters in nerve fibres?

    <p>To transmit information between neurons</p> Signup and view all the answers

    Which statement about ganglia is correct?

    <p>Ganglia exclusively contain either sensory neurons or autonomic neurons.</p> Signup and view all the answers

    What constitutes a nerve plexus?

    <p>A network of intermingled nerve fibres</p> Signup and view all the answers

    What condition is associated with cauda equina syndrome?

    <p>Herniated disk compressing nerve roots</p> Signup and view all the answers

    Which of the following correctly describes a characteristic of spinal nerves?

    <p>Spinal nerves are a part of the peripheral nervous system.</p> Signup and view all the answers

    What is a defining trait of mixed nerves?

    <p>They carry both motor and sensory information.</p> Signup and view all the answers

    Which of the following best describes the composition of nerve fibres?

    <p>Nerve fibres consist of myelinated and unmyelinated axons.</p> Signup and view all the answers

    How are sensory ganglia different from autonomic ganglia?

    <p>They are distinguished by the types of neurons they contain.</p> Signup and view all the answers

    Why can a single nerve fibre only carry one type of stimulus?

    <p>Nerve fibres are specialized to transmit specific signals.</p> Signup and view all the answers

    What is a primary function of the peripheral nervous system (PNS)?

    <p>Connecting the brain and spinal cord to the periphery</p> Signup and view all the answers

    How many pairs of spinal nerves are present in the human body?

    <p>31 pairs</p> Signup and view all the answers

    What best describes a nerve plexus?

    <p>A network of nerve fibres that form complex structures</p> Signup and view all the answers

    Which of the following is an example of a nerve plexus?

    <p>Brachial plexus</p> Signup and view all the answers

    What is the role of autonomic ganglia in the peripheral nervous system?

    <p>They are involved in autonomic nervous system functions, including regulation of organs.</p> Signup and view all the answers

    Which feature distinguishes sensory ganglia from autonomic ganglia?

    <p>Sensory ganglia contain sensory neurons, while autonomic ganglia contain neurons of the autonomic nervous system.</p> Signup and view all the answers

    What best describes the function of the anterior rami of spinal nerves?

    <p>They form the brachial and lumbar plexuses.</p> Signup and view all the answers

    What structure is primarily responsible for the formation of the myelin sheath in the PNS?

    <p>Schwann cells</p> Signup and view all the answers

    Which part of the spinal nerve contains both sensory and motor fibres?

    <p>Mixed rami</p> Signup and view all the answers

    Which spinal nerve root carries sensory information?

    <p>Posterior root</p> Signup and view all the answers

    What is the primary function of the cervical plexus?

    <p>To provide sensory innervation to the skin of the neck and head</p> Signup and view all the answers

    Which type of nerve fibres carry information from sensory receptors to the CNS?

    <p>Afferent fibres</p> Signup and view all the answers

    Which nerve is part of the sacral plexus?

    <p>Sciatic nerve</p> Signup and view all the answers

    What is a ganglion in the peripheral nervous system?

    <p>A collection of nerve cell bodies</p> Signup and view all the answers

    Which structure in the spinal cord contains the cell bodies of autonomic neurons?

    <p>Lateral horn</p> Signup and view all the answers

    Which type of nerve fibres is primarily involved in reflex actions?

    <p>Both sensory and motor fibres</p> Signup and view all the answers

    What is the main role of the sympathetic division of the autonomic nervous system?

    <p>To mediate 'fight or flight' responses</p> Signup and view all the answers

    Which of the following structures contains the cell bodies of sensory neurons in the peripheral nervous system?

    <p>The dorsal root ganglion</p> Signup and view all the answers

    What is the primary function of the cauda equina?

    <p>To provide a pathway for lower spinal nerves to exit the vertebral column</p> Signup and view all the answers

    Which type of neurons are primarily found in the anterior horn of the spinal cord?

    <p>Motor neurons</p> Signup and view all the answers

    Which of the following is NOT a component of a peripheral nerve?

    <p>Cerebrospinal fluid</p> Signup and view all the answers

    What is the main role of Schwann cells in the peripheral nervous system?

    <p>To form myelin sheaths around axons</p> Signup and view all the answers

    Which plexus serves the arm and shoulder region?

    <p>Brachial plexus</p> Signup and view all the answers

    What type of fibers does the anterior root of a spinal nerve contain?

    <p>Motor fibers only</p> Signup and view all the answers

    Which term describes the gaps between myelinated segments of an axon?

    <p>Nodes of Ranvier</p> Signup and view all the answers

    Which structure is primarily responsible for the striated appearance of peripheral nerves?

    <p>The arrangement of nerve fibers in parallel</p> Signup and view all the answers

    Which of the following correctly describes the function of efferent fibers in peripheral nerves?

    <p>They carry motor commands to peripheral muscles.</p> Signup and view all the answers

    What structure in the spinal cord is associated with the formation of the cauda equina?

    <p>The conus medullaris</p> Signup and view all the answers

    Which statement about the blood supply to peripheral nerves is accurate?

    <p>Peripheral nerves have blood vessels parallel to their fibers.</p> Signup and view all the answers

    Which condition is characterized by the compression of nerve roots in the cauda equina?

    <p>Cauda equina syndrome</p> Signup and view all the answers

    Study Notes

    Central Nervous System

    • Contains the brain and spinal cord
    • Protected and nourished by meninges
    • Immersed in Cerebrospinal Fluid (CSF)
    • Made up of both white and grey matter
    • Highly vascularized

    Brain

    • Divided into the cerebrum, brainstem, and cerebellum
    • Cerebrum:
      • Consists of two hemispheres: right and left
      • Five lobes: frontal, parietal, temporal, occipital, and insula
    • Brainstem:
      • Final part of the brain before the spinal cord begins
    • Cerebellum:
      • Connected to the dorsal aspect of the brainstem

    Neurons and Neurotransmitters

    • Neurons are the basic functional units of the nervous system
    • Neurotransmitters are chemical messengers that transmit signals between neurons
    • Neurotransmitters are stored in vesicles within the presynaptic neuron
    • When a signal arrives at the presynaptic neuron, neurotransmitters are released into the synaptic cleft
    • The neurotransmitters bind to receptors on the postsynaptic neuron, triggering a response.

    Glial Cells

    • Glial cells are non-neuronal cells found in the nervous system
    • Glial cells support and protect neurons, providing structural support, insulation, and nutrient supply.

    Astrocytes

    • Astrocytes are a type of glial cell that provide structural support and help maintain the blood-brain barrier
    • Astrocytes also form scars in the central nervous system (CNS) following injuries.

    Oligodendrocytes

    • Oligodendrocytes are glial cells that form the myelin sheath, a fatty substance that insulates axons and allows for faster signal transmission.

    Microglia

    • Microglia are immune cells in the CNS that play a crucial role in immune surveillance and response to injury or infection.

    Central Nervous System (CNS)

    • The CNS is composed of the brain and spinal cord.
    • The CNS can be divided into grey matter and white matter.

    Grey Matter

    • Grey matter contains neuron cell bodies, dendrites, and synapses.
    • Grey matter plays a critical role in processing information and controlling movement, sensory perception and higher cognitive functions.

    White Matter

    • White matter is primarily composed of myelinated axons that transmit signals between different parts of the nervous system.
    • White matter appears white due to the myelin sheath.

    CNS White Matter: Oligodendrocytes and Myelin

    • Oligodendrocytes wrap their cell membranes around axons in a concentric manner to form the myelin sheath.
    • This myelin sheath acts as an insulator, speeding up the transmission of nerve impulses.

    White and Gray Matter: Distribution

    • Grey matter is found in the outer layers of the brain, forming the cerebral cortex and basal ganglia.
    • White matter is found in the inner layers of the brain and within the spinal cord.

    CNS White Matter: Fibre Types

    • Association fibres connect different regions of the same hemisphere of the brain.
    • Commissural fibres connect the two hemispheres of the brain.
    • Projection fibres connect the brain to other parts of the CNS, such as the spinal cord.

    Axon Myelination

    • Myelination is a process of segmental wrapping of axons, with gaps between the segments called the nodes of Ranvier.
    • This segmental myelination allows for saltatory conduction, where the nerve impulse jumps from node to node, significantly increasing the speed of signal transmission.

    Blood-Brain Barrier

    • The CNS is highly vascularized, meaning it has a dense network of blood vessels.
    • The blood-brain barrier is a protective mechanism that restricts the movement of substances from the bloodstream into the brain tissue.
    • The blood-brain barrier is formed by tight junctions between endothelial cells lining the brain capillaries.
    • Astrocyte endfeet contribute to the blood-brain barrier by providing structural support and regulating the permeability of the capillaries.
    • The blood-brain barrier is important for maintaining the stability of the brain environment and protecting it from harmful substances.
    • Some drugs cannot cross the blood-brain barrier, limiting their effectiveness in treating CNS disorders.
    • In certain conditions, such as meningitis, the blood-brain barrier can become permeable, allowing for the entry of antibiotics to treat the infection.
    • The breakdown of the blood-brain barrier is implicated in the pathogenesis of various diseases, including multiple sclerosis (MS).

    Peripheral Nerves

    • Peripheral nerves connect the CNS to the periphery.
    • They are composed of nerve fibers.
    • Afferent fibers travel from the periphery (receptors) towards the CNS.
    • Efferent fibers travel from the CNS towards the periphery (effectors).
    • Nerve fibers in the PNS are either myelinated or non-myelinated.
    • Myelinated fibers have a myelin sheath that increases the speed of signal transmission.
    • Non-myelinated fibers lack a myelin sheath and have slower signal transmission.
    • Nerve plexi are networks of nerve fibers found in the PNS, often outside the spinal cord.
    • Ganglia in the PNS contain the cell bodies of neurons.
    • Ganglia are either sensory ganglia or autonomic ganglia.

    Spinal Nerves

    • Spinal nerves are part of the PNS.
    • There are 31 pairs of spinal nerves.
    • These nerves connect the spinal cord to the periphery.
    • Cauda equina is a bundle of nerve roots at the bottom of the spinal cord that resembles a horse's tail.
    • Cauda equina syndrome is a medical emergency caused by compression of the cauda equina nerve roots.
    • Symptoms include back pain, weakness in the legs, and incontinence.
    • Prompt surgical treatment is required to prevent permanent complications.

    Structure and Organisation of Spinal Nerves

    • Each spinal nerve is formed by the merging of a dorsal root and a ventral root.
    • The dorsal root contains sensory fibers, which carry information from the periphery to the spinal cord.
    • The ventral root contains motor fibers, which carry signals from the spinal cord to muscles and glands.
    • The rami are branches of spinal nerves.
    • Anterior rami continue to the upper and lower extremities, forming networks called plexuses.
    • Cervical plexus provides innervation to the neck and shoulders.
    • Brachial plexus innervates the upper limbs.
    • Lumbar plexus innervates the lower limbs.
    • Sacral plexus innervates the lower limbs and pelvic organs.
    • Intercostal nerves originate from the thoracic region of the spinal cord and provide innervation to the chest, abdomen, and back.

    Peripheral Nervous System (PNS)

    • The PNS connects the central nervous system (CNS) - brain and spinal cord - to the rest of the body
    • Responsible for transmitting sensory and motor signals between the CNS and periphery
    • Composed of 31 pairs of spinal nerves and 12 pairs of cranial nerves

    Spinal Nerves

    • Nerve Plexus: A network of interwoven nerves that form complex structures
    • Brachial Plexus: A network of nerves serving the arm and shoulder regions
    • Anterior Rami: Formed by the ventral branches of spinal nerves, and contribute to the brachial and lumbar plexuses
    • Posterior Rami: Supply the skin and muscles of the back
    • Cauda Equina Syndrome: Occurs when the nerve roots in the lower spinal cord are compressed, leading to weakness and incontinence
    • Conus Medullaris: The conical lower end of the spinal cord, contributes to the cauda equina

    Nerve Fibres

    • Myelin Sheath: Insulating layer around axons made by Schwann cells within the peripheral nervous system
    • Schwann cells are responsible for forming the myelin sheath in the peripheral nervous system
    • Nodes of Ranvier: Gaps between Schwann cells where axons are exposed to extracellular fluid, helping accelerate nerve impulses

    Nerve Structure

    • Endoneurium: Thin connective tissue layer surrounding individual nerve fibres
    • Perineurium: Connective tissue layer surrounding nerve bundles
    • Epineurium: Outer connective tissue layer surrounding the entire nerve, protecting and separating nerve bundles

    Neuron Types

    • Sensory Neurons: Located in the dorsal root ganglia, transmit info from sensory receptors to the CNS
    • Motor Neurons: Located in the anterior horn of the spinal cord, carry motor signals from the CNS to muscles

    Autonomic Nervous System

    • Autonomic Ganglia: Collections of nerve cell bodies in the PNS involved in autonomic nervous system functions
    • Sympathetic Nervous System: Prepares the body for "fight or flight" responses
    • Parasympathetic Nervous System: Responsible for "rest and digest" functions

    Spinal Cord

    • White Matter: Contains myelinated axons, responsible for conducting motor and sensory impulses
    • Grey Matter: Contains neuron cell bodies, involved in processing and relaying information

    Other Structures that are not as important

    • Dorsal Root Ganglia: Contains the cell bodies of sensory neurons
    • Lateral Horn: Region of the spinal cord containing cell bodies of autonomic neurons
    • Cervical Plexus: Provides sensory innervation to the skin of the neck and head
    • Lumbar Plexus: Serves the lower limbs and pelvis
    • Sacral Plexus: Serves the lower limbs and pelvis
    • Sciatic Nerve: Part of the sacral plexus, serves the lower limbs
    • Phrenic Nerve: Innervates the diaphragm
    • Medial Nerve: Part of the brachial plexus, serves the hand
    • Femoral Nerve: Part of the lumbar plexus, serves the thigh

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    Description

    Explore the key components and functions of the Central Nervous System, including the brain and spinal cord. This quiz covers the structure of the brain, its divisions, and the protective elements surrounding it. Test your knowledge on the anatomy and physiology of this crucial system!

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