Podcast
Questions and Answers
What is the role of dynamin in endocytosis?
What is the role of dynamin in endocytosis?
- Induce more PIP2 hydrolysis
- Gather at the neck to create higher curvature and recruit phosphatase (correct)
- Create higher membrane curvature
- Transport and sort vesicles based on receptor type or membrane composition
How does clathrin assist in vesicle formation?
How does clathrin assist in vesicle formation?
- Directly associates with the membrane to form the vesicle
- Acts as a scaffold protein that polymerizes and forms a cage around the vesicle (correct)
- Binds with caveolin to drive membrane deformation
- Is a tetrameric adaptor complex for coated vesicles
What initiates clathrin complex formation?
What initiates clathrin complex formation?
- Dynamin-induced vesicle scission
- Presence of adaptor protein and PIP2 accumulation (correct)
- Dissociation of the coat after scission
- Formation of coated vesicles by Ap2
What drives membrane deformation in caveolin-mediated endocytosis?
What drives membrane deformation in caveolin-mediated endocytosis?
What is the pH of early endosomes and how are they identified?
What is the pH of early endosomes and how are they identified?
Which of the following is NOT a key step in the trafficking of vesicles?
Which of the following is NOT a key step in the trafficking of vesicles?
Which type of endocytosis involves the capture and destruction of pathogens and some antigens as part of the immune response?
Which type of endocytosis involves the capture and destruction of pathogens and some antigens as part of the immune response?
Which of the following statements about the size of vesicles formed during different endocytic processes is correct?
Which of the following statements about the size of vesicles formed during different endocytic processes is correct?
Which type of endocytosis involves the binding of substances to specific receptors on the cell surface?
Which type of endocytosis involves the binding of substances to specific receptors on the cell surface?
Which of the following is responsible for the rapid recruitment of dynamin to the neck of a forming vesicle during clathrin-mediated endocytosis?
Which of the following is responsible for the rapid recruitment of dynamin to the neck of a forming vesicle during clathrin-mediated endocytosis?
Which of the following is NOT a function of Rab GTPases in endocytosis?
Which of the following is NOT a function of Rab GTPases in endocytosis?
What is the primary function of the phosphatase that is recruited to the endocytic site during clathrin-mediated endocytosis?
What is the primary function of the phosphatase that is recruited to the endocytic site during clathrin-mediated endocytosis?
What is the primary function of the PIP2 phase segregation that occurs during clathrin-mediated endocytosis?
What is the primary function of the PIP2 phase segregation that occurs during clathrin-mediated endocytosis?
How do the Ap2 adaptor protein subunits contribute to clathrin-mediated endocytosis?
How do the Ap2 adaptor protein subunits contribute to clathrin-mediated endocytosis?
Which of the following is a key difference between clathrin-mediated endocytosis and caveolin-mediated endocytosis?
Which of the following is a key difference between clathrin-mediated endocytosis and caveolin-mediated endocytosis?
