lecture 1
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Questions and Answers

Which domain includes animals, plants, fungi, and protists?

  • Domain Prokaryota
  • Domain Archaea
  • Domain Eucaryota (correct)
  • Domain Bacteria
  • Which domain is not part of the division of cellular life forms?

  • Domain Bacteria
  • Domain Archaea
  • Domain Eucaryota
  • Domain Prokaryota (correct)
  • What does the small subunit of ribosomes contain?

  • One 16S rRNA molecule (correct)
  • Multiple tRNA molecules
  • Both 16S and 18S rRNA molecules
  • One 18S rRNA molecule
  • How many subunits make up ribosomes?

    <p>Two (small and large)</p> Signup and view all the answers

    What is compared to determine relatedness among organisms?

    <p>Sequence of nucleotide base pairs in the gene coding for the 16S rRNA molecule</p> Signup and view all the answers

    How many DNA nucleotides does the gene that codes for the 16S rRNA molecule contain?

    <p>About 1500 DNA nucleotides</p> Signup and view all the answers

    What is the function of the 16S rRNA molecule?

    <p>To help determine relatedness among organisms</p> Signup and view all the answers

    What is the composition of viroids?

    <p>Short, single-stranded RNA molecule</p> Signup and view all the answers

    What is the typical length of a viroid RNA molecule?

    <p>A few hundred nucleotides</p> Signup and view all the answers

    What is the role of viroids in plants?

    <p>Cause diseases</p> Signup and view all the answers

    What is the nature of Hepatitis D virus (HDV)?

    <p>It is a viroid</p> Signup and view all the answers

    What distinguishes viroids from typical viruses?

    <p>They lack a protein-coding capacity</p> Signup and view all the answers

    What is the normal location of prion protein (PrPC) in the human cell?

    <p>On the surface of the cell</p> Signup and view all the answers

    What is the abbreviation for the normal prion protein?

    <p>PrPC</p> Signup and view all the answers

    Where is the abnormal form of prion protein (PrPSc) commonly found?

    <p>In the brain tissue</p> Signup and view all the answers

    What is the abnormal form of prion protein (PrPSc) able to induce in specific normal cellular proteins (PrPC)?

    <p>Abnormal folding</p> Signup and view all the answers

    What is a characteristic of prion diseases?

    <p>Extremely resistant to inactivation by UV light and X-rays</p> Signup and view all the answers

    How do prion diseases respond to commonly known antimicrobial substances?

    <p>Do not respond to currently known antimicrobial substances</p> Signup and view all the answers

    What are virulence factors?

    <p>Properties of pathogenic microorganisms that allow them to invade the human body and/or produce toxins</p> Signup and view all the answers

    What type of flasks did Louis Pasteur use in his experiment?

    <p>Swan-neck flasks</p> Signup and view all the answers

    What concept did Louis Pasteur's experiment support?

    <p>Biogenesis</p> Signup and view all the answers

    Why did the nutrient broth remain clear in the swan-neck flasks?

    <p>Preventing airborne microorganisms from contaminating it</p> Signup and view all the answers

    What is the second criteria in Robert Koch's postulates for confirming the causative microbial agent of a disease?

    <p>The pathogen must be isolated in a pure culture</p> Signup and view all the answers

    What is the third criteria in Robert Koch's postulates for confirming the causative microbial agent of a disease?

    <p>The pathogen isolated from pure culture must cause the same disease in a healthy, susceptible laboratory animal</p> Signup and view all the answers

    What is the fourth criteria in Robert Koch's postulates for confirming the causative microbial agent of a disease?

    <p>The pathogen must be reisolated from the inoculated laboratory animal</p> Signup and view all the answers

    What is the first criteria in Koch's postulates for confirming the causative microbial agent of a disease?

    <p>The same pathogen must be present in every case of the disease</p> Signup and view all the answers

    What is the characteristic of sporadic disease?

    <p>It occurs infrequently and irregularly</p> Signup and view all the answers

    What defines an endemic disease?

    <p>The constant presence and/or usual prevalence in a population within a geographic area</p> Signup and view all the answers

    What is hyperendemic disease known for?

    <p>Persistent, high levels of disease occurrence</p> Signup and view all the answers

    What is the main difference between epidemic and pandemic diseases?

    <p>Epidemic diseases affect a specific population in an area, while pandemic diseases spread over multiple countries or continents</p> Signup and view all the answers

    What does pandemic disease refer to?

    <p>An epidemic that has spread over several countries or continents, usually affecting a large number of people</p> Signup and view all the answers

    How is systemic infection spread throughout the body?

    <p>Via blood circulation</p> Signup and view all the answers

    What is a latent infection characterized by?

    <p>The potential to become active at some time</p> Signup and view all the answers

    What does mixed infection involve?

    <p>Two or more pathogens infecting the same tissue</p> Signup and view all the answers

    Which type of infection is characterized by pus formation?

    <p>Pyogenic infection</p> Signup and view all the answers

    What is the defining feature of a fulminant infection?

    <p>Sudden and intense onset</p> Signup and view all the answers

    Which type of infection occurs suddenly and intensely?

    <p>Fulminant infection</p> Signup and view all the answers

    What does the Iceberg Concept of Disease Occurrence illustrate?

    <p>The visibility of only a small fraction of diagnosed cases</p> Signup and view all the answers

    What is the emphasis of the Iceberg Concept in relation to disease control?

    <p>Surveillance and public health efforts</p> Signup and view all the answers

    What is the proportion of diagnosed cases in the Iceberg Concept of Disease Occurrence?

    <p>Small fraction</p> Signup and view all the answers

    How does excessive iron affect susceptibility to infections?

    <p>It increases susceptibility to infections</p> Signup and view all the answers

    Why do bacteria need iron?

    <p>For growth and metabolism</p> Signup and view all the answers

    What is the relationship between iron and bacterial growth?

    <p>Iron is essential for bacterial growth</p> Signup and view all the answers

    How do some bacteria directly scavenge iron from the host?

    <p>By targeting iron-binding proteins like transferrin and lactoferrin</p> Signup and view all the answers

    What is the role of siderophores in bacterial iron acquisition?

    <p>Chelating and transporting available iron into bacterial cells</p> Signup and view all the answers

    Which pathogen has adapted to not require iron for its survival?

    <p>Treponema pallidum</p> Signup and view all the answers

    What controls the production of Diphtheria toxin in bacteria?

    <p>DtxR repressor, activated by iron</p> Signup and view all the answers

    Under what conditions is Diphtheria toxin synthesized by lysogenic bacteria?

    <p>Iron-deficient conditions</p> Signup and view all the answers

    Which toxin's production is known to be depressed by iron?

    <p>Shiga-like toxin</p> Signup and view all the answers

    What happens to the level of P. aeruginosa exotoxin A when the iron concentration increases?

    <p>It decreases</p> Signup and view all the answers

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