Cell Transport Mechanisms Quiz
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Questions and Answers

What is the primary distinction between diffusion and active transport?

Diffusion involves the passive movement of substances through the membrane, while active transport requires energy to carry substances against their concentration gradient.

Explain the processes of pinocytosis and phagocytosis.

Pinocytosis is the ingestion of minute particles and extracellular fluid, while phagocytosis involves the ingestion of large particles like bacteria and dead cells.

How do substances like vitamin B12 and iron enter cells?

Vitamin B12 and iron combine with specific proteins and enter cells via endocytosis through receptor-mediated mechanisms.

What cellular mechanisms are involved in phagocytosis initiation?

<p>Phagocytosis begins when a particle binds to receptors on a phagocyte's surface, often mediated by antibodies attached to the particle.</p> Signup and view all the answers

Why is pinocytosis especially rapid in macrophages?

<p>Pinocytosis is rapid in macrophages because they constantly engulf extracellular fluid and particles, with about 3% of their membrane being engulfed each minute.</p> Signup and view all the answers

What role do protein structures play in active transport across cell membranes?

<p>Protein structures penetrate the membrane and actively carry substances across it, often against their concentration gradient.</p> Signup and view all the answers

In what way does endocytosis facilitate the entry of large or lipid-insoluble chemicals into cells?

<p>Endocytosis allows these substances to be engulfed by the cell membrane, forming vesicles that bring them into the cytoplasm.</p> Signup and view all the answers

What percentage of the total macrophage membrane is typically engulfed via pinocytosis each minute?

<p>About 3 percent of the total macrophage membrane is engulfed through pinocytosis each minute.</p> Signup and view all the answers

What does Fick's law predict in terms of molecular movement?

<p>Fick's law predicts the rate of movement of molecules across a barrier based on the concentration gradient and permeability coefficient.</p> Signup and view all the answers

Explain the role of macromolecules in carrier-mediated diffusion.

<p>Macromolecules facilitate the movement of specific substances across the membrane without using energy.</p> Signup and view all the answers

How does carrier-mediated diffusion differ from Fick's law?

<p>Carrier-mediated diffusion is not governed by Fick's law and is capacity-limited, unlike aqueous and lipid diffusion.</p> Signup and view all the answers

What is the significance of selective inhibitors in transport mechanisms?

<p>Selective inhibitors can enhance the therapeutic effects of drugs by altering their transport across barriers.</p> Signup and view all the answers

Describe facilitated diffusion and its requirements.

<p>Facilitated diffusion involves the movement of specific molecules through protein channels across the cell membrane without needing energy.</p> Signup and view all the answers

What distinguishes active transport from passive transport processes?

<p>Active transport requires energy to move substances against their concentration gradient, while passive processes do not.</p> Signup and view all the answers

How does osmosis function in terms of water movement?

<p>Osmosis is the diffusion of water from areas of high water concentration to low water concentration across a semi-permeable membrane.</p> Signup and view all the answers

Why is it essential for cells to obtain nutrients from surrounding fluids?

<p>Cells must obtain nutrients to live, grow, and reproduce, relying on diffusion and active transport to facilitate this process.</p> Signup and view all the answers

What is the process called whereby antibodies facilitate the phagocytosis of pathogens?

<p>The process is called opsonization.</p> Signup and view all the answers

List the first step that occurs during phagocytosis.

<p>Cell membrane receptors attach to the surface ligands of the particle.</p> Signup and view all the answers

What role do actin and contractile fibrils play in phagocytosis?

<p>They surround the phagocytic vesicle and contract to push it into the cell interior.</p> Signup and view all the answers

What substance do lysosomes release into the phagocytic vesicle to aid digestion?

<p>Lysosomes release acid hydrolases.</p> Signup and view all the answers

Name two bactericidal agents found in lysosomes that help eliminate phagocytized bacteria.

<p>Lysozyme and lysoferrin.</p> Signup and view all the answers

What happens to the indigestible substances remaining in a digestive vesicle?

<p>They become a residual body, which is excreted through exocytosis.</p> Signup and view all the answers

What are the foodstuffs that enter mitochondria to react with oxygen?

<p>Glucose, fatty acids, and amino acids.</p> Signup and view all the answers

How do enzymes influence the reactions inside mitochondria?

<p>Enzymes control the reactions and direct the energy released in a proper manner.</p> Signup and view all the answers

What role does the lipid bilayer play in cellular transport?

<p>The lipid bilayer acts as a barrier against the movement of water molecules and water-soluble substances between the extracellular and intracellular fluid compartments.</p> Signup and view all the answers

What distinguishes simple diffusion from facilitated diffusion?

<p>Simple diffusion involves the kinetic movement of molecules through membrane openings without carrier proteins, while facilitated diffusion requires carrier proteins to aid in the passage of molecules.</p> Signup and view all the answers

Describe the process and requirement of active transport.

<p>Active transport involves the movement of ions or other substances against an energy gradient using a carrier protein, requiring an additional source of energy.</p> Signup and view all the answers

What is aqueous diffusion and how does it occur in capillaries?

<p>Aqueous diffusion is the movement of molecules through the watery extracellular and intracellular spaces, occurring in capillaries via small water-filled pores allowing small proteins to diffuse.</p> Signup and view all the answers

What types of substances typically undergo lipid diffusion, and why?

<p>Substances like oxygen, nitrogen, carbon dioxide, and alcohols undergo lipid diffusion due to their high lipid solubility, allowing them to dissolve in the lipid bilayer.</p> Signup and view all the answers

How does the structure of the membrane influence diffusion?

<p>The structure of the membrane, specifically its lipid bilayer, dictates the selective permeability and facilitates either passive or facilitated diffusion.</p> Signup and view all the answers

Why is energy required for active transport but not for diffusion?

<p>Energy is required for active transport because it moves substances against their concentration gradient, while diffusion occurs down a gradient and relies on kinetic energy.</p> Signup and view all the answers

What passive mechanisms govern the process of aqueous diffusion?

<p>Aqueous diffusion is governed by passive mechanisms such as Fick's law, which describes the diffusion rate based on concentration differences.</p> Signup and view all the answers

Study Notes

Functional Systems of the Cell: Transport

  • Cells require transport of substances across the cell membrane to maintain homeostasis and function.
  • The lipid bilayer acts as a barrier, preventing the free movement of water and water-soluble substances between extracellular and intracellular fluids.
  • Membrane transport occurs through passive and active mechanisms.

Passive Transport

  • Diffusion: Random movement of molecules, either through membrane spaces or with carrier proteins. It's driven by the kinetic energy of molecules moving from high to low concentration.
  • Types of Diffusion:
    • Simple diffusion: Movement through intermolecular spaces or directly across the lipid bilayer for lipid-soluble molecules.
    • Facilitated diffusion: Movement assisted by carrier proteins, essential for larger or insoluble molecules, still from high to low concentration gradient.
  • Aqueous diffusion: Movement of molecules through the watery extracellular and intracellular spaces, common in capillaries. This is a passive process following Fick's Law.
  • Lipid diffusion: Movement of molecules through membranes, driven by lipid solubility.
  • Fick's law: Predicts the rate of movement of molecules across a barrier, influenced by concentration gradient, permeability coefficient, area, and thickness of the barrier.

Active Transport

  • Active transport: Movement of ions or other substances against an energy gradient (often from low to high concentration) using carrier proteins and an energy source beyond kinetic energy. Requires ATP.
  • Carrier-mediated diffusion: Substances move with a carrier protein, but does not move against the concentration gradient, utilizing no energy.

Transport by Special Carriers

  • Drugs can be transported across barriers by specialized carrier mechanisms (e.g., amino acid carriers in the blood-brain barrier, weak acid carriers in the renal tubules).
  • Carrier transport isn't governed by Fick's law and is capacity-limited.
  • Selective inhibitors of these carriers (like probenecid) can be useful clinically (e.g., increasing uric acid excretion).

Endocytosis

  • Cells take in large particles via endocytosis.
  • Types of Endocytosis:
    • Pinocytosis: Ingestion of minute particles, creating vesicles of extracellular fluid.
    • Phagocytosis: Ingestion of large particles (bacteria, cells).
  • Mechanism: Membrane engulfs particles (often via receptor binding), forming vesicles, transporting the molecules inside the cell.
  • Very large or insoluble molecules need this mechanism.
  • Opsonization: Bacteria attach to antibodies to assist in cell engulfment.

Phagocytosis Steps

  • Cell membrane receptors attach to ligands on a particle.
  • Membrane engulfs the particle.
  • Cytoplasmic actin and other contractile fibrils surround the vesicle, pushing it inwards until the particle is fully inside.
  • Contractile proteins pinch off the vesicle, creating another intracellular vesicle inside the cell.

Lysosomes

  • Almost immediately after endocytosis, lysosomes fuse with the vesicle, releasing digestive enzymes within the particles.
  • Digestive vesicle is formed with enzymes hydrolyzing proteins, carbohydrates, lipids, etc., producing basic molecules like amino acids, glucose,etc. that diffuse to the cytoplasm.
  • Lysosomes contain bactericidal agents (lysozyme, lysoferrin, acid) to destroy engulfed bacteria, or other foreign matter, before causing cellular damage.
  • Indigestible remains become residual bodies and are eliminated from the cell by exocytosis.

Mitochondria

  • Mitochondria are organelles responsible for cellular respiration and energy production.
  • Foodstuffs are oxidized with oxygen inside mitochondria, releasing energy used to make ATP (adenosine triphosphate), which is the main energy currency for cells.
  • ATP is used for various cellular processes (active transport, synthesis, and mechanical work (muscle contraction)).

General Cell Concepts

  • Cellular transport mechanisms are essential for maintaining homeostasis and normal cellular operation.

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Related Documents

Cell Membrane Transport PDF

Description

Test your knowledge on various cell transport mechanisms, including diffusion, active transport, pinocytosis, and phagocytosis. Delve into how substances like vitamin B12 and iron enter cells, and understand the roles of protein structures and macromolecules in these processes. Explore the differences between active and passive transport, and the significance of selective inhibitors.

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