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Questions and Answers
What kind of experiments are required to figure out how cell signaling pathways work?
What kind of experiments are required to figure out how cell signaling pathways work?
- Experiments to determine the location of the cell signaling pathways
- Experiments to determine the structure of the cell signaling pathways
- Experiments to determine which proteins interact with a given receptor and which ligand activates a given receptor (correct)
- Experiments to determine the size of the cell signaling pathways
What is the purpose of constructing a series of mutant receptors, each missing a different tyrosine from its cytoplasmic domain?
What is the purpose of constructing a series of mutant receptors, each missing a different tyrosine from its cytoplasmic domain?
- To determine the stability of the mutant receptors
- To determine the size of the mutant receptors
- To determine which phosphorylated tyrosine on a RTK is recognized by a certain intracellular signaling protein (correct)
- To determine the color of the mutant receptors
What kind of questions can be answered by experiments in untangling cell signaling pathways?
What kind of questions can be answered by experiments in untangling cell signaling pathways?
- Which proteins interact with a given receptor and what role does a particular protein play in a signaling pathway (correct)
- Which proteins interact with a given ligand and what role does a particular ligand play in a signaling pathway
- Which ligand activates a given receptor and which receptor is activated by a given ligand
- Which ligand activates a given protein and which protein is activated by a given ligand
What is required to figure out which parts of the proteins are necessary for interaction?
What is required to figure out which parts of the proteins are necessary for interaction?
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What kind of mutants can help in determining which phosphorylated tyrosine on a RTK is recognized by a certain intracellular signaling protein?
What kind of mutants can help in determining which phosphorylated tyrosine on a RTK is recognized by a certain intracellular signaling protein?
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